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Identifying measurable genetic indicators (or biomarkers) of a specific condition of a biological system is a key element of precision medicine. Indeed it allows to tailor diagnostic, prognostic and treatment choice to individual…

Machine Learning · Statistics 2016-12-16 Chloé-Agathe Azencott

We propose a new approach for clustering DNA features using array CGH data from multiple tumor samples. We distinguish data-collapsing: joining contiguous DNA clones or probes with extremely similar data into regions, from clustering:…

Applications · Statistics 2010-12-21 Kyung In Kim , Etienne Roquain , Mark Van De Wiel

Explainability is key to enhancing artificial intelligence's trustworthiness in medicine. However, several issues remain concerning the actual benefit of explainable models for clinical decision-making. Firstly, there is a lack of consensus…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Kazuma Kobayashi , Yasuyuki Takamizawa , Mototaka Miyake , Sono Ito , Lin Gu , Tatsuya Nakatsuka , Yu Akagi , Tatsuya Harada , Yukihide Kanemitsu , Ryuji Hamamoto

Most classification methods are based on the assumption that data conforms to a stationary distribution. The machine learning domain currently suffers from a lack of classification techniques that are able to detect the occurrence of a…

Machine Learning · Statistics 2012-01-05 Alzennyr Da Silva , Yves Lechevallier , Fabrice Rossi , Francisco De A. T. De Carvahlo

Clustering methods are popular for revealing structure in data, particularly in the high-dimensional setting common to contemporary data science. A central statistical question is, "are the clusters really there?" One pioneering method in…

Methodology · Statistics 2023-08-28 Thomas H. Keefe , J. S. Marron

Subspace clustering aims to find groups of similar objects (clusters) that exist in lower dimensional subspaces from a high dimensional dataset. It has a wide range of applications, such as analysing high dimensional sensor data or DNA…

Machine Learning · Computer Science 2018-11-08 Minh Tuan Doan , Jianzhong Qi , Sutharshan Rajasegarar , Christopher Leckie

We consider the problem of clustering a set of high-dimensional data points into sets of low-dimensional linear subspaces. The number of subspaces, their dimensions, and their orientations are unknown. We propose a simple and low-complexity…

Information Theory · Computer Science 2013-03-18 Reinhard Heckel , Helmut Bölcskei

Unsupervised classification is a fundamental machine learning problem. Real-world data often contain imperfections, characterized by uncertainty and imprecision, which are not well handled by traditional methods. Evidential clustering,…

Machine Learning · Computer Science 2025-08-08 Victor F. Lopes de Souza , Karima Bakhti , Sofiane Ramdani , Denis Mottet , Abdelhak Imoussaten

Machine learning is revolutionizing nutrition science by enabling systems to learn from data and make intelligent decisions. However, the complexity of these models often leads to challenges in understanding their decision-making processes,…

Machine Learning · Computer Science 2024-10-21 Fanyu Meng , Jules Larke , Xin Liu , Zhaodan Kong , Xin Chen , Danielle Lemay , Ilias Tagkopoulos

Subspace clustering methods based on expressing each data point as a linear combination of all other points in a dataset are popular unsupervised learning techniques. However, existing methods incur high computational complexity on…

Machine Learning · Computer Science 2019-08-05 Farhad Pourkamali-Anaraki

Relationship between agents can be conveniently represented by graphs. When these relationships have different modalities, they are better modelled by multilayer graphs where each layer is associated with one modality. Such graphs arise…

Machine Learning · Statistics 2021-03-05 Guillaume Braun , Hemant Tyagi , Christophe Biernacki

Deep learning methods have been very effective for a variety of medical diagnostic tasks and has even beaten human experts on some of those. However, the black-box nature of the algorithms has restricted clinical use. Recent explainability…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Amitojdeep Singh , Sourya Sengupta , Vasudevan Lakshminarayanan

Understanding and extracting the patterns of microscopy images has been a major challenge in the biomedical field. Although trained scientists can locate the proteins of interest within a human cell, this procedure is not efficient and…

Computer Vision and Pattern Recognition · Computer Science 2020-06-09 Hanke Chen

We propose a novel method for multiple clustering that assumes a co-clustering structure (partitions in both rows and columns of the data matrix) in each view. The new method is applicable to high-dimensional data. It is based on a…

We present a structural clustering algorithm for large-scale datasets of small labeled graphs, utilizing a frequent subgraph sampling strategy. A set of representatives provides an intuitive description of each cluster, supports the…

Databases · Computer Science 2016-10-03 Till Schäfer , Petra Mutzel

A learning classifier must outperform a trivial solution, in case of imbalanced data, this condition usually does not hold true. To overcome this problem, we propose a novel data level resampling method - Clustering Based Oversampling for…

Machine Learning · Computer Science 2018-11-13 Naman D. Singh , Abhinav Dhall

Deep learning has significantly advanced electrocardiogram (ECG) analysis, enabling automatic annotation, disease screening, and prognosis beyond traditional clinical capabilities. However, understanding these models remains a challenge,…

Machine Learning · Computer Science 2025-09-19 Ahcène Boubekki , Konstantinos Patlatzoglou , Joseph Barker , Fu Siong Ng , Antônio H. Ribeiro

Model-based clustering is widely used for identifying and distinguishing types of diseases. However, modern biomedical data coming with high dimensions make it challenging to perform the model estimation in traditional cluster analysis. The…

Methodology · Statistics 2025-07-22 Kazeem Kareem , Fan Dai

Clinical time series data are critical for patient monitoring and predictive modeling. These time series are typically multivariate and often comprise hundreds of heterogeneous features from different data sources. The grouping of features…

Machine Learning · Computer Science 2025-11-12 Fedor Sergeev , Manuel Burger , Polina Leshetkina , Vincent Fortuin , Gunnar Rätsch , Rita Kuznetsova

We present a technique for clustering categorical data by generating many dissimilarity matrices and averaging over them. We begin by demonstrating our technique on low dimensional categorical data and comparing it to several other…

Machine Learning · Statistics 2017-09-20 Saeid Amiri , Bertrand Clarke , Jennifer Clarke