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A genome read data set can be quickly and efficiently remapped from one reference to another similar reference (e.g., between two reference versions or two similar species) using a variety of tools, e.g., the commonly-used CrossMap tool.…

Genomics · Quantitative Biology 2023-11-21 Jeremie S. Kim , Can Firtina , Meryem Banu Cavlak , Damla Senol Cali , Can Alkan , Onur Mutlu

Motivation: Seed filtering is critical in DNA read mapping, a process where billions of DNA fragments (reads) sampled from a donor are mapped onto a reference genome to identify genomic variants of the donor. Read mappers 1) quickly…

In many retrieval systems the original high dimensional data (e.g., images) is mapped to a lower dimensional feature through a learned embedding model. The task of retrieving the most similar data from a gallery set to a given query data is…

Computer Vision and Pattern Recognition · Computer Science 2023-03-09 Florian Jaeckle , Fartash Faghri , Ali Farhadi , Oncel Tuzel , Hadi Pouransari

Current popular methods for Magnetic Resonance Fingerprint (MRF) recovery are bottlenecked by the heavy computations of a matched-filtering step due to the growing size and complexity of the fingerprint dictionaries in multi-parametric…

Computer Vision and Pattern Recognition · Computer Science 2018-10-05 Mohammad Golbabaee , Zhouye Chen , Yves Wiaux , Mike Davies

There are currently plenty of programs available for mapping short sequences (reads) to a genome. Most of them, however, including such popular and actively developed programs as Bowtie, BWA, TopHat and many others, are based on…

Genomics · Quantitative Biology 2019-08-06 Igor Seledtsov , Jaroslav Efremov , Vladimir Molodtsov , Victor Solovyev

Existing UAV vision-and-language navigation (VLN) benchmarks rarely provide realistic aerial scenes, natural process-level instructions, and sufficient scale simultaneously, making it difficult to systematically train and evaluate UAV VLN…

Computation and Language · Computer Science 2026-05-18 Hengxing Cai , Yijie Rao , Ligang Huang , Zanyang Zhong , Jinhan Dong , Jingjun Tan , Changhao Nai , Jue Hou , Wenhao Lu , Renxin Zhong

Simultaneous machine translation (SiMT) generates translation while reading the whole source sentence. However, existing SiMT models are typically trained using the same reference disregarding the varying amounts of available source…

Computation and Language · Computer Science 2023-10-27 Shoutao Guo , Shaolei Zhang , Yang Feng

Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from revealing the proteins' common origin. Moreover, when a large number of…

Quantitative Methods · Quantitative Biology 2011-01-18 Marta L. Gîrdea , Laurent Noé , Gregory Kucherov

Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. Modern sequencing platforms generate enormous amounts of…

Schema matching is a crucial task in data integration, involving the alignment of a source schema with a target schema to establish correspondence between their elements. This task is challenging due to textual and semantic heterogeneity,…

Databases · Computer Science 2024-05-31 Eitam Sheetrit , Menachem Brief , Moshik Mishaeli , Oren Elisha

With the increasing affordability and accessibility of genome sequencing data, de novo genome assembly is an important first step to a wide variety of downstream studies and analyses. Therefore, bioinformatics tools that enable the…

Genomics · Quantitative Biology 2023-06-09 Lauren Coombe , René L. Warren , Johnathan Wong , Vladimir Nikolic , Inanc Birol

We introduce Air Learning, an open-source simulator, and a gym environment for deep reinforcement learning research on resource-constrained aerial robots. Equipped with domain randomization, Air Learning exposes a UAV agent to a diverse set…

Robotics · Computer Science 2022-11-15 Srivatsan Krishnan , Behzad Boroujerdian , William Fu , Aleksandra Faust , Vijay Janapa Reddi

Motivation: Seed location filtering is critical in DNA read mapping, a process where billions of DNA fragments (reads) sampled from a donor are mapped onto a reference genome to identify genomic variants of the donor. State-of-the-art read…

Accurate anatomical labeling and analysis of the pulmonary structure and its surrounding anatomy from thoracic CT is getting increasingly important for understanding the etilogy of abnormalities or supporting targetted therapy and early…

Image and Video Processing · Electrical Eng. & Systems 2025-05-09 Minghui Zhang , Chenyu Li , Fangfang Xie , Yaoyu Liu , Hanxiao Zhang , Junyang Wu , Chunxi Zhang , Jie Yang , Jiayuan Sun , Guang-Zhong Yang , Yun Gu

Accelerated magnetic resonance imaging involves reconstructing fully sampled images from undersampled k-space measurements. Current state-of-the-art approaches have mainly focused on either end-to-end supervised training inspired by…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Xinzhe Luo , Yingzhen Li , Chen Qin

Large language models (LLMs) are increasingly used to automate data analysis through executable code generation. Yet, data science tasks often admit multiple statistically valid solutions, e.g. different modeling strategies, making it…

Machine Learning · Computer Science 2025-11-10 Qiuhai Zeng , Claire Jin , Xinyue Wang , Yuhan Zheng , Qunhua Li

Genome analysis fundamentally starts with a process known as read mapping, where sequenced fragments of an organism's genome are compared against a reference genome. Read mapping is currently a major bottleneck in the entire genome analysis…

Hardware Architecture · Computer Science 2020-10-29 Mohammed Alser , Zülal Bingöl , Damla Senol Cali , Jeremie Kim , Saugata Ghose , Can Alkan , Onur Mutlu

If we cannot inspect the training data of a large language model (LLM), how can we ever know what it has seen? We believe the most compelling evidence arises when the model itself freely reproduces the target content. As such, we propose…

Computation and Language · Computer Science 2026-03-16 André V. Duarte , Xuying li , Bin Zeng , Arlindo L. Oliveira , Lei Li , Zhuo Li

This paper studies Automated Instruction Revision (AIR), a rule-induction-based method for adapting large language models (LLMs) to downstream tasks using limited task-specific examples. We position AIR within the broader landscape of…

Computation and Language · Computer Science 2026-04-13 Solomiia Bilyk , Volodymyr Getmanskyi , Taras Firman

In the paper, we introduce a paper reading assistant, PaperHelper, a potent tool designed to enhance the capabilities of researchers in efficiently browsing and understanding scientific literature. Utilizing the Retrieval-Augmented…

Computation and Language · Computer Science 2025-02-21 Congrui Yin , Evan Wei , Zhongxing Zhang , Zaifu Zhan
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