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Diffusion Tensor Imaging (DTI) is an effective tool for the analysis of structural brain connectivity in normal development and in a broad range of brain disorders. However efforts to derive inherent characteristics of structural brain…

Computational Engineering, Finance, and Science · Computer Science 2018-02-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

Motivation: Lack of tools for comprehensive and complete segmentation of deep grey nuclei using a single software for reproducibility and repeatability Goal(s): A fast accurate and robust method for segmentation of deep grey nuclei…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Manojkumar Saranathan , Giuseppina Cogliandro , Thomas Hicks , Dianne Patterson , Behroze Vachha , Alberto Cacciola

Diffusion Magnetic Resonance Imaging (MRI) exploits the anisotropic diffusion of water molecules in the brain to enable the estimation of the brain's anatomical fiber tracts at a relatively high resolution. In particular, tractographic…

Computational Engineering, Finance, and Science · Computer Science 2016-09-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

Parcellation of human cerebellar pathways is essential for advancing our understanding of the human brain. Existing diffusion MRI tractography parcellation methods have been successful in defining major cerebellar fibre tracts, while…

Multimodal MRI provides critical complementary information for accurate brain tumor segmentation. However, conventional methods struggle when certain modalities are missing due to issues such as image quality, protocol inconsistencies,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Runze Cheng , Xihang Qiu , Ming Li , Ye Zhang , Chun Li , Fei Yu

Understanding the relationship between the dynamics of neural processes and the anatomical substrate of the brain is a central question in neuroscience. On the one hand, modern neuroimaging technologies, such as diffusion tensor imaging,…

The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…

Understanding brain connectivity has become one of the most important issues in neuroscience. But connectivity data can reflect either the functional relationships of the brain activities or the anatomical properties between brain areas.…

Neurons and Cognition · Quantitative Biology 2015-04-13 Tiago Simas , Mario Chavez , Pablo Rodriguez , Albert Diaz-Guilera

Brain nuclei are clusters of anatomically distinct neurons that serve as important hubs for processing and relaying information in various neural circuits. Fine-scale parcellation of the brain nuclei is vital for a comprehensive…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Haolin He , Ce Zhu , Le Zhang , Yipeng Liu , Xiao Xu , Yuqian Chen , Leo Zekelman , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Lauren J. O'Donnell , Fan Zhang

Deep learning approaches for diffusion MRI have so far focused primarily on voxel-based segmentation of lesions or white-matter fiber tracts. A drawback of representing tracts as volumetric labels, rather than sets of streamlines, is that…

Image and Video Processing · Electrical Eng. & Systems 2020-09-10 Christian Ewert , David Kügler , Anastasia Yendiki , Martin Reuter

The amygdala plays a vital role in emotional processing and exhibits structural diversity that necessitates fine-scale parcellation for a comprehensive understanding of its anatomico-functional correlations. Diffusion MRI tractography is an…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Haolin He , Ce Zhu , Le Zhang , Yipeng Liu , Xiao Xu , Yuqian Chen , Leo Zekelman , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Lauren J. O'Donnell , Fan Zhang

Segmentation is crucial for brain gliomas as it delineates the glioma s extent and location, aiding in precise treatment planning and monitoring, thus improving patient outcomes. Accurate segmentation ensures proper identification of the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Kiranmayee Janardhan , Vinay Martin DSa Prabhu , T. Christy Bobby

Automatic image segmentation becomes very crucial for tumor detection in medical image processing.In general, manual and semi automatic segmentation techniques require more time and knowledge. However these drawbacks had overcome by…

Computer Vision and Pattern Recognition · Computer Science 2016-03-09 D. Anithadevi , K. Perumal

Multimodal neuroimaging modeling has becomes a widely used approach but confronts considerable challenges due to heterogeneity, which encompasses variability in data types, scales, and formats across modalities. This variability…

Neurons and Cognition · Quantitative Biology 2025-04-15 Gang Qu , Ziyu Zhou , Vince D. Calhoun , Aiying Zhang , Yu-Ping Wang

Five different threshold segmentation based approaches have been reviewed and compared over here to extract the tumor from set of brain images. This research focuses on the analysis of image segmentation methods, a comparison of five…

Computer Vision and Pattern Recognition · Computer Science 2015-03-10 Muhammad Ali Qadar , Yan Zhaowen

As the largest human cerebellar nucleus, the dentate nucleus (DN) functions significantly in the communication between the cerebellum and the rest of the brain. Structural connectivity-based parcellation has the potential to reveal the…

Image and Video Processing · Electrical Eng. & Systems 2023-01-23 Xiao Xu , Yuqian Chen , Leo Zekelman , Yogesh Rathi , Nikos Makris , Fan Zhang , Lauren J. O'Donnell

The hypothalamus plays an important role in the regulation of the bodys metabolic state and behaviors related to survival. Despite its importance however, many questions exist regarding the intrinsic and extrinsic connections of the…

Brain atlases are a ubiquitous tool used for analyzing and interpreting brain imaging datasets. Traditionally, brain atlases divided the brain into regions separated by anatomical landmarks. In the last decade, several attempts have been…

Quantitative Methods · Quantitative Biology 2018-02-08 Pantea Moghimi , Kelvin O. Lim , Theoden I. Netoff

Diffusion-weighted Magnetic Resonance Imaging (dMRI) is increasingly used to study the fetal brain in utero. An important computation enabled by dMRI is streamline tractography, which has unique applications such as tract-specific analysis…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Camilo Calixto , Camilo Jaimes , Matheus D. Soldatelli , Simon K. Warfield , Ali Gholipour , Davood Karimi

Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging technique that enables in vivo mapping of the brain's white matter connections at macro scale. Over the last two decades, the study of brain connectivity using…

Quantitative Methods · Quantitative Biology 2021-04-26 Fan Zhang , Alessandro Daducci , Yong He , Simona Schiavi , Caio Seguin , Robert Smith , Chun-Hung Yeh , Tengda Zhao , Lauren J. O'Donnell