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The ability to automatically detect, classify, calculate the size, number, and grade of retinal cells and other biological objects is critically important in eye disease like age-related macular degeneration (AMD). In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2020-10-01 S. M. Hadi Hosseini , Hao Chen , Monica M. Jablonski

Segmentation of retinal layers from Optical Coherence Tomography (OCT) volumes is a fundamental problem for any computer aided diagnostic algorithm development. This requires preprocessing steps such as denoising, region of interest…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Karthik Gopinath , Samrudhdhi B Rangrej , Jayanthi Sivaswamy

According to the World Health Organization, 285 million people worldwide live with visual impairment. The most commonly used imaging technique for diagnosis in ophthalmology is optical coherence tomography (OCT). However, analysis of…

Computer Vision and Pattern Recognition · Computer Science 2019-04-02 Max-Heinrich Laves , Sontje Ihler , Lüder A. Kahrs , Tobias Ortmaier

In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Mohammad Sadegh Gholizadeh , Amir Arsalan Rezapour

Despite the revolutionary impact of AI and the development of locally trained algorithms, achieving widespread generalized learning from multi-modal data in medical AI remains a significant challenge. This gap hinders the practical…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Fatema-E Jannat , Sina Gholami , Minhaj Nur Alam , Hamed Tabkhi

Predicting future disease progression risk from medical images is challenging due to patient heterogeneity, and subtle or unknown imaging biomarkers. Moreover, deep learning (DL) methods for survival analysis are susceptible to image domain…

Diabetic retinopathy (DR) results in vision loss if not treated early. A computer-aided diagnosis (CAD) system based on retinal fundus images is an efficient and effective method for early DR diagnosis and assisting experts. A…

Computer Vision and Pattern Recognition · Computer Science 2019-08-23 Norah Asiri , Muhammad Hussain , Fadwa Al Adel , Nazih Alzaidi

Background: The lack of explanations for the decisions made by algorithms such as deep learning has hampered their acceptance by the clinical community despite highly accurate results on multiple problems. Recently, attribution methods have…

Image and Video Processing · Electrical Eng. & Systems 2021-03-26 Amitojdeep Singh , J. Jothi Balaji , Mohammed Abdul Rasheed , Varadharajan Jayakumar , Rajiv Raman , Vasudevan Lakshminarayanan

Deep learning has emerged as a transformative approach for solving complex pattern recognition and object detection challenges. This paper focuses on the application of a novel detection framework based on the RT-DETR model for analyzing…

Computer Vision and Pattern Recognition · Computer Science 2025-01-29 Weijie He , Yuwei Zhang , Ting Xu , Tai An , Yingbin Liang , Bo Zhang

Diabetic retinopathy (DR) is a significant cause of vision impairment, emphasizing the critical need for early detection and timely intervention to avert visual deterioration. Diagnosing DR is inherently complex, as it necessitates the…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Mohamed R. Shoaib , Heba M. Emara , Jun Zhao , Walid El-Shafai , Naglaa F. Soliman , Ahmed S. Mubarak , Osama A. Omer , Fathi E. Abd El-Samie , Hamada Esmaiel

Objective: The advent of Electronic Medical Records (EMR) with large electronic imaging databases along with advances in deep neural networks with machine learning has provided a unique opportunity to achieve milestones in automated image…

Machine Learning · Statistics 2016-12-16 Cecilia S. Lee , Doug M. Baughman , Aaron Y. Lee

Automatic clinical diagnosis of retinal diseases has emerged as a promising approach to facilitate discovery in areas with limited access to specialists. Based on the fact that fundus structure and vascular disorders are the main…

Computer Vision and Pattern Recognition · Computer Science 2018-11-05 C. -H. Huck Yang , Fangyu Liu , Jia-Hong Huang , Meng Tian , Hiromasa Morikawa , I-Hung Lin , Yi-Chieh Liu , Hao-Hsiang Yang , Jesper Tegner

Retinal diseases such as Diabetic Retinopathy (DR) and Macular Hole (MH) significantly impact vision and affect millions worldwide. Early detection is crucial, as DR, a complication of diabetes, damages retinal blood vessels, potentially…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Duaa Kareem Qasim , Sabah Abdulazeez Jebur , Lafta Raheem Ali , Abdul Jalil M. Khalaf , Abir Jaafar Hussain

Optical Coherence Tomography (OCT) provides valuable insights in ophthalmology, cardiology, and neurology due to high-resolution, cross-sectional images of the retina. One critical task for ophthalmologists using OCT is delineation of…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Samuel T. M. Ball

Optical coherence tomography (OCT) is a non-invasive imaging modality which is widely used in clinical ophthalmology. OCT images are capable of visualizing deep retinal layers which is crucial for early diagnosis of retinal diseases. In…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Peyman Gholami , Priyanka Roy , Mohana Kuppuswamy Parthasarathy , Vasudevan Lakshminarayanan

Diabetic retinopathy (DR) is a retinal microvascular condition that emerges in diabetic patients. DR will continue to be a leading cause of blindness worldwide, with a predicted 191.0 million globally diagnosed patients in 2030.…

Computer Vision and Pattern Recognition · Computer Science 2020-10-23 Mihir Rao , Michelle Zhu , Tianyang Wang

In recent years, the focus is on improving the diagnosis of diabetic retinopathy (DR) using machine learning and deep learning technologies. Researchers have explored various approaches, including the use of high-definition medical imaging,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Saideep Kilaru , Kothamasu Jayachandra , Tanishka Yagneshwar , Suchi Kumari

Advances in optical coherence tomography (OCT) have enabled noninvasive imaging of substructures of the human retina with high spatial resolution. OCT examinations are now a standard procedure in clinics and an integral part of ophthalmic…

Human-Computer Interaction · Computer Science 2022-12-22 Martin Röhlig , Oliver Stachs , Heidrun Schumann

The ultra-wide optical coherence tomography angiography (OCTA) has become an important imaging modality in diabetic retinopathy (DR) diagnosis. However, there are few researches focusing on automatic DR analysis using ultra-wide OCTA. In…

Image and Video Processing · Electrical Eng. & Systems 2022-10-04 Junlin Hou , Fan Xiao , Jilan Xu , Yuejie Zhang , Haidong Zou , Rui Feng

Multiple-surface segmentation in Optical Coherence Tomography (OCT) images is a challenge problem, further complicated by the frequent presence of weak image boundaries. Recently, many deep learning (DL) based methods have been developed…

Image and Video Processing · Electrical Eng. & Systems 2022-10-13 Hui Xie , Weiyu Xu , Xiaodong Wu