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Single-cell RNA-seq provides detailed molecular snapshots of individual cells but is notoriously noisy. Variability stems from biological differences and technical factors, such as amplification bias and limited RNA capture efficiency,…

Machine Learning · Computer Science 2026-02-27 Victor Chardès

Uniform Manifold Approximation and Projection (UMAP) is a widely used manifold learning technique for dimensionality reduction. This paper studies UMAP, supervised UMAP, and several competing dimensionality reduction methods, including…

Machine Learning · Computer Science 2026-05-04 Guanzhe Zhang , Shanshan Ding , Zhezhen Jin

Principal components analysis (PCA) is the optimal linear auto-encoder of data, and it is often used to construct features. Enforcing sparsity on the principal components can promote better generalization, while improving the…

Machine Learning · Computer Science 2015-02-25 Malik Magdon-Ismail , Christos Boutsidis

This paper introduces a new unsupervised method for dimensionality reduction via regression (DRR). The algorithm belongs to the family of invertible transforms that generalize Principal Component Analysis (PCA) by using curvilinear instead…

Machine Learning · Statistics 2016-02-02 Valero Laparra , Jesus Malo , Gustau Camps-Valls

Principal component analysis (PCA) can be significantly limited when there is too few examples of the target data of interest. We propose a transfer learning approach to PCA (TL-PCA) where knowledge from a related source task is used in…

Machine Learning · Computer Science 2024-10-15 Sharon Hendy , Yehuda Dar

The implementation of conventional sparse principal component analysis (SPCA) on high-dimensional data sets has become a time consuming work. In this paper, a series of subspace projections are constructed efficiently by using Household QR…

Machine Learning · Statistics 2019-12-09 Cong Xu , Min Yang , Jin Zhang

Our aim is to evaluate fundamental parameters from the analysis of the electromagnetic spectra of stars. We may use $10^3$-$10^5$ spectra; each spectrum being a vector with $10^2$-$10^4$ coordinates. We thus face the so-called "curse of…

Instrumentation and Methods for Astrophysics · Physics 2017-06-08 V. Watson , JF. Trouilhet , F. Paletou , S. Girard

Dimension-reduction techniques can greatly improve statistical inference in astronomy. A standard approach is to use Principal Components Analysis (PCA). In this work we apply a recently-developed technique, diffusion maps, to astronomical…

Astrophysics · Physics 2011-02-11 Joseph W. Richards , Peter E. Freeman , Ann B. Lee , Chad M. Schafer

We study the problem of supervised linear dimensionality reduction, taking an information-theoretic viewpoint. The linear projection matrix is designed by maximizing the mutual information between the projected signal and the class label…

Machine Learning · Computer Science 2012-07-03 Minhua Chen , William Carson , Miguel Rodrigues , Robert Calderbank , Lawrence Carin

Principal component analysis (PCA) is a classical method for dimensionality reduction based on extracting the dominant eigenvectors of the sample covariance matrix. However, PCA is well known to behave poorly in the ``large $p$, small $n$''…

Statistics Theory · Mathematics 2009-08-26 Arash A. Amini , Martin J. Wainwright

Background: Single-cell RNA sequencing (scRNA-seq) enables gene expression profiling at cellular resolution but is inherently affected by sparsity caused by dropout events, where expressed genes are recorded as zeros due to technical…

Genomics · Quantitative Biology 2026-04-15 Yuichiro Iwashita , Ahtisham Fazeel Abbasi , Koichi Kise , Andreas Dengel , Muhammad Nabeel Asim

Dimensionality reduction represents a critical preprocessing step in order to increase the efficiency and the performance of many hyperspectral imaging algorithms. However, dimensionality reduction algorithms, such as the Principal…

Machine Learning · Computer Science 2024-03-28 E. Martel , R. Lazcano , J. Lopez , D. Madroñal , R. Salvador , S. Lopez , E. Juarez , R. Guerra , C. Sanz , R. Sarmiento

Recently neural network based approaches to knowledge-intensive NLP tasks, such as question answering, started to rely heavily on the combination of neural retrievers and readers. Retrieval is typically performed over a large textual…

Information Retrieval · Computer Science 2022-04-20 Vilém Zouhar , Marius Mosbach , Miaoran Zhang , Dietrich Klakow

Hyperspectral optical imaging provides rich spectral information for estimating continuous environmental and material parameters; however, its high dimensionality and strong feature correlation pose significant challenges for machine…

Optics · Physics 2025-12-18 Parisa Parand , Mahmoud Samadpour

Principal component analysis (PCA) is a widely used technique for data analysis and dimension reduction with numerous applications in science and engineering. However, the standard PCA suffers from the fact that the principal components…

Optimization and Control · Mathematics 2009-07-14 Zhaosong Lu , Yong Zhang

Projections (or dimensionality reduction) methods $P$ aim to map high-dimensional data to typically 2D scatterplots for visual exploration. Inverse projection methods $P^{-1}$ aim to map this 2D space to the data space to support tasks such…

Human-Computer Interaction · Computer Science 2026-02-12 Yu Wang , Frederik L. Dennig , Michael Behrisch , Alexandru Telea

Sparse principal component analysis (SPCA) has emerged as a powerful technique for modern data analysis, providing improved interpretation of low-rank structures by identifying localized spatial structures in the data and disambiguating…

Dimensionality reduction is a main step in the learning process which plays an essential role in many applications. The most popular methods in this field like SVD, PCA, and LDA, only can be applied to data with vector format. This means…

Machine Learning · Computer Science 2019-03-01 Soheil Ahmadi , Mansoor Rezghi

Principal Component Analysis (PCA) is a powerful and popular dimensionality reduction technique. However, due to its linear nature, it often fails to capture the complex underlying structure of real-world data. While Kernel PCA (kPCA)…

Machine Learning · Computer Science 2026-02-05 Thomas Uriot , Elise Chung

We introduce a new framework for dimension reduction in the context of high-dimensional regression. Our proposal is to aggregate an ensemble of random projections, which have been carefully chosen based on the empirical regression…

Methodology · Statistics 2024-10-08 Wenxing Zhou , Timothy I. Cannings
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