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Related papers: Automated Thalamic Nuclei Segmentation Using Multi…

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Purpose: Thalamic nuclei are largely invisible in conventional MRI due to poor contrast. Thalamus Optimized Multi-Atlas Segmentation (THOMAS) provides automatic segmentation of 12 thalamic nuclei using white-matter-nulled (WMn) MPRAGE…

Image and Video Processing · Electrical Eng. & Systems 2020-06-30 Ritobrato Datta , Micky K. Bacchus , Dushyant Kumar , Mark A. Elliott , Aditya Rao , Sudipto Dolui , Ravinder Reddy , Brenda L Banwell , Manojkumar Saranathan

Thalamic nuclei have been implicated in several neurological diseases. WMn-MPRAGE images have been shown to provide better intra-thalamic nuclear contrast compared to conventional MPRAGE images but the additional acquisition results in…

Machine Learning · Computer Science 2020-12-18 Lavanya Umapathy , Mahesh Bharath Keerthivasan , Natalie M. Zahr , Ali Bilgin , Manojkumar Saranathan

Accurate segmentation of thalamic nuclei is important for better understanding brain function and improving disease treatment. Traditional segmentation methods often rely on a single T1-weighted image, which has limited contrast in the…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Anqi Feng , Zhangxing Bian , Blake E. Dewey , Alexa Gail Colinco , Jiachen Zhuo , Jerry L. Prince

The thalamus and its constituent nuclei are critical for a broad range of cognitive and sensorimotor processes, and implicated in many neurological and neurodegenerative conditions. However, the functional involvement and specificity of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Brendan Williams , Dan Nguyen , Julie Vidal , Alzheimer's Disease Neuroimaging Initiative , Manojkumar Saranathan

Accurate segmentation of thalamic nuclei from magnetic resonance images is important due to the distinct roles of these nuclei in overall brain function and to their differential involvement in neurological and psychiatric disorders.…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Anqi Feng , Zhangxing Bian , Samuel W. Remedios , Savannah P. Hays , Blake E. Dewey , Alexa Colinco , Jiachen Zhuo , Dan Benjamini , Jerry L. Prince

The human thalamus is a highly connected subcortical grey-matter structure within the brain. It comprises dozens of nuclei with different function and connectivity, which are affected differently by disease. For this reason, there is…

Thalamic alterations are relevant to many neurological disorders including Alzheimer's disease, Parkinson's disease and multiple sclerosis. Routine interventions to improve symptom severity in movement disorders, for example, often consist…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Veronica Corona , Jan Lellmann , Peter Nestor , Carola-Bibiane Schoenlieb , Julio Acosta-Cabronero

Accurate thalamic nuclei segmentation is crucial for understanding neurological diseases, brain functions, and guiding clinical interventions. However, the optimal inputs for segmentation remain unclear. This study systematically evaluates…

Image and Video Processing · Electrical Eng. & Systems 2025-08-19 Anqi Feng , Zhangxing Bian , Samuel W. Remedios , Savannah P. Hays , Blake E. Dewey , Jiachen Zhuo , Dan Benjamini , Jerry L. Prince

The implication of the thalamus in multiple neurological pathologies makes it a structure of interest for volumetric analysis. In the present work, we have designed and implemented a multimodal volumetric deep neural network for the…

The thalamus is a subcortical structure of central importance to brain function, which is organized in smaller nuclei with specialized roles. Despite significant functional and clinical relevance, locating and distinguishing the different…

The thalamus consists of several histologically and functionally distinct nuclei increasingly implicated in brain pathology and important for treatment, motivating the need for development of fast and accurate thalamic segmentation. The…

Image and Video Processing · Electrical Eng. & Systems 2019-12-19 Charles Iglehart , Martin Monti , Joshua Cain , Thomas Tourdias , Manojkumar Saranathan

Accurate segmentation of thalamic nuclei, crucial for understanding their role in healthy cognition and in pathologies, is challenging to achieve on standard T1-weighted (T1w) magnetic resonance imaging (MRI) due to poor image contrast.…

Image and Video Processing · Electrical Eng. & Systems 2023-04-17 Julie P. Vidal , Lola Danet , Patrice Péran , Jérémie Pariente , Meritxell Bach Cuadra , Natalie M. Zahr , Emmanuel J. Barbeau , Manojkumar Saranathan

The thalamus is a subcortical gray matter structure that plays a key role in relaying sensory and motor signals within the brain. Its nuclei can atrophy or otherwise be affected by neurological disease and injuries including mild traumatic…

Image and Video Processing · Electrical Eng. & Systems 2023-02-02 Chang Yan , Muhan Shao , Zhangxing Bian , Anqi Feng , Yuan Xue , Jiachen Zhuo , Rao P. Gullapalli , Aaron Carass , Jerry L. Prince

Motivation: Lack of tools for comprehensive and complete segmentation of deep grey nuclei using a single software for reproducibility and repeatability Goal(s): A fast accurate and robust method for segmentation of deep grey nuclei…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Manojkumar Saranathan , Giuseppina Cogliandro , Thomas Hicks , Dianne Patterson , Behroze Vachha , Alberto Cacciola

Tumor volume segmentation on MRI is a challenging and time-consuming process that is performed manually in typical clinical settings. This work presents an approach to automated delineation of head and neck tumors on MRI scans, developed in…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Andrei Iantsen

In this paper, we present a novel automated method for White Matter (WM) lesion segmentation of Multiple Sclerosis (MS) patient images. Our approach is based on a cascade of two 3D patch-wise convolutional neural networks (CNN). The first…

Segmentation of structural and diffusion MRI (sMRI/dMRI) is usually performed independently in neuroimaging pipelines. However, some brain structures (e.g., globus pallidus, thalamus and its nuclei) can be extracted more accurately by…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Juan Eugenio Iglesias , Koen Van Leemput , Polina Golland , Anastasia Yendiki

The human thalamus is a brain structure that comprises numerous, highly specific nuclei. Since these nuclei are known to have different functions and to be connected to different areas of the cerebral cortex, it is of great interest for the…

A cascade of fully convolutional neural networks is proposed to segment multi-modal Magnetic Resonance (MR) images with brain tumor into background and three hierarchical regions: whole tumor, tumor core and enhancing tumor core. The…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Guotai Wang , Wenqi Li , Sebastien Ourselin , Tom Vercauteren

Carotid arteries vulnerable plaques are a crucial factor in the screening of atherosclerosis by ultrasound technique. However, the plaques are contaminated by various noises such as artifact, speckle noise, and manual segmentation may be…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Yanchao Yuan , Cancheng Li , Lu Xu , Ke Zhang , Yang Hua , Jicong Zhang
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