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Microfluidic devices can be used to produce highly controlled and monodisperse double or multiple emulsions. The presence of inner drops inside a jet of the middle phase introduces deformations in the jet, which leads to breakup into…

Engineering simple, artificial models of living cells allows synthetic biologists to study cellular functions under well-controlled conditions. Reconstituting multicellular behaviors with synthetic cell-mimics is still a challenge because…

Biomolecules · Quantitative Biology 2021-04-29 Imre Banlaki , Francois-Xavier Lehr , Henrike Niederholtmeyer

Superheated perfluorocarbon nanodroplets are emerging ultrasound imaging contrast agents boasting biocompatible components, unique phase-change dynamics, and therapeutic loading capabilities. Upon exposure to a sufficiently high intensity…

Medical Physics · Physics 2021-03-31 Austin Van Namen , Sidhartha Jandhyala , Tomas Jordan , Geoffrey Luke

Chemical bioreactions play a significant role in many of the microfluidic devices, and their applications in biomedical science have seen substantial growth. Given that effective mixing is vital for initiating biochemical reactions in many…

Fluid Dynamics · Physics 2024-02-13 Ali Kheirkhah Barzoki

Microfluidic has been an enabling technology for over a decade, particularly in the field of medical and wearable devices, allowing for the manipulation of small amounts of fluid in confined spaces. Micro-channels can also be used for…

Systems and Control · Electrical Eng. & Systems 2024-04-16 Giulio Maria Bianco , Gaetano Marrocco

A new type of microfluidic system for biological cell manipulation, a CMOS/microfluidic hybrid, is demonstrated. The hybrid system starts with a custom-designed CMOS (complementary metal-oxide semiconductor) chip fabricated in a…

Quantitative Methods · Quantitative Biology 2007-05-23 Hakho Lee , Yong Liu , Donhee Ham , Robert M. Westervelt

Among the various molecular imaging modalities, ultrasound imaging benefits from its real-time, nonionizing, and cost-effective nature. Despite its benefits, there is a dearth of methods to visualize two or more populations of contrast…

Image and Video Processing · Electrical Eng. & Systems 2023-10-03 Austin Van Namen , Sidhartha Jandhyala , Catalina-Paula Spatarelu , Kenneth M. Tichauer , Kimberley S. Samkoe , Geoffrey P. Luke

Microfluidic technology provides a solution to the challenge of continuous CaCO$_3$ particle synthesis. In this study, we utilized a 3D-printed microfluidic chip to synthesize CaCO$_3$ micro and nanoparticles in vaterite form. Our primary…

The development of compact and bright XUV and soft X-ray sources based on high-order harmonic generation is boosting advances towards understanding the behavior of matter with extreme temporal and spatial resolutions. Here, we report…

Previous devices to separate cells by the characteristic force they experience due to dielectrophoresis, which depends on the size and electric properties of the particle, were limited by the flow rates and particle concentrations…

Applied Physics · Physics 2020-09-08 Ngoc-Duy Dinh , Dinh-Tuan Phan

We have developed an original setup using microfluidic tools allowing one to produce continuously monodisperse microreactors ($\approx 100$ nL), and to control their temperatures as they flow in the microdevice. With a specific…

Soft Condensed Matter · Physics 2009-11-11 Philippe Laval , Jean-Baptiste Salmon , Mathieu Joanicot

The emerging field of deformable microfluidics widely employed in the Lab-on-a-Chip and MEMS communities offers an opportunity to study a relatively under-examined physics. The main objective of this work is to provide a deeper insight into…

Fluid Dynamics · Physics 2018-09-14 Aryan Mehboudi , Junghoon Yeom

Nanocarriers are nanosized materials commonly used for targeted-oriented delivery of active compounds, including antimicrobials and small-molecular drugs. They equally represent fundamental and engineering challenges since sophisticated…

Soft Condensed Matter · Physics 2021-01-19 François Sicard , Jhoan Toro-Mendoza

Droplet microfluidics are a powerful approach for hydrogel cell encapsulations. Much of the field has focused on single-cell encapsulations with pico-nanoliter droplet volumes necessary for single-cell sequencing or high-throughput…

To facilitate the use and portability of Lab on a chip technology, it is desirable to avoid the use of bulky electronic systems for flow control. Developed self-powered microsystems typically move only small volumes of fluid performing up…

This study presents a three-dimensional transient computational fluid dynamics simulation of droplet generation in a flow-focusing microfluidic device using the Coupled Level Set and Volume of Fluid method for interface capturing. We…

Fluid Dynamics · Physics 2025-07-17 Manohar Jammula , Somasekhara Goud Sontti

Methylammonium lead iodide perovskite has attracted intensive interest for its diverse optoelectronic applications. However, most studies to date have been limited to bulk thin films that are difficult to implement for integrated device…

Ultrasound is a key technology in healthcare, and it is being explored for non-invasive, wearable, continuous monitoring of vital signs. However, its widespread adoption in this scenario is still hindered by the size, complexity, and power…

Current developments in molecular electronics, motors and chemical sensors could enable constructing large numbers of devices able to sense, compute and act in micron-scale environments. Such microscopic machines, of sizes comparable to…

Robotics · Computer Science 2023-02-03 Tad Hogg

The displacement of a more viscous fluid by a less viscous immiscible fluid in confined geometries is a fundamental problem in multiphase flows. Recent experiments have shown that such fluid-fluid displacement in micro-capillary tubes can…

Fluid Dynamics · Physics 2025-12-01 Sthavishtha R. Bhopalam , Ruben Juanes , Hector Gomez