Related papers: Aortic and arterial mechanics
Mechanical properties are intrinsically related to the structures and dynamics of systems. The main tools to investigate mechanical properties are rheology and microrheology. Those techniques can focus on the macroscopic and microscopic…
Biological membranes mainly consist of lipids and proteins. While the proteins have many functions as single molecules, the membrane as a whole displays physical properties that cannot be explained on the single molecule level. For example,…
Abdominal aortic aneurysms (AAAs) are pathologic dilatations of the abdominal aorta posing a high fatality risk upon rupture. Studying AAA progression and rupture risk often involves in-silico blood flow modelling with computational fluid…
The biomechanical properties of blood clots, which are dictated by their compositions and micro-structures, play a critical role in determining their fates, occlusion, persistency, or embolization in the human circulatory system. While…
This work provides a comprehensive overview of the fundamental concepts in continuum mechanics, focusing on the behaviour of materials under mechanical loads. It discusses the distinction between elastic and plastic, highlighting their…
This review focuses on the computerized modeling of the electrophysiology of the human atria, emphasizing the simulation of common arrhythmias such as atrial flutter (AFlut) and atrial fibrillation (AFib). Which components of the model are…
The action potential is widely considered a purely electrical phenomenon. However, one also finds mechanical and thermal changes that can be observed experimentally. In particular, nerve membranes become thicker and axons contract. The…
Abdominal Aortic Aneurysm (AAA) is an enlargement in the lower part of the main artery Aorta by 1.5 times its normal diameter. AAA can cause death if rupture occurs. Elective surgeries are recommended to prevent rupture based on geometrical…
Accurate prediction of aortic expansion in uncomplicated type B aortic dissection (TBAD) can help identify patients who may benefit from timely thoracic endovascular aortic repair. This study investigates associations between biomechanical…
Mechanical algesia is an important process for the preservation of living organisms, allowing potentially life-saving reflexes or decisions when given body parts are stressed. Yet, its various underlying mechanisms remain to be fully…
Networks of elastic beams can deform either by stretching or bending of their members. The primary mode of deformation (bending or stretching) crucially depends on the specific details of the network architecture. In order to shed light on…
Aortic shape analysis plays a key role in cardiovascular diagnostics, treatment planning, and understanding disease progression. We present a robust, fully automated pipeline for aortic shape analysis from cardiac MRI, combining deep…
In complex crystals close to melting or at finite temperatures, different types of defects are ubiquitous and their role becomes relevant in the mechanical response of these solids. Conventional elasticity theory fails to provide a…
Numerical simulations have been extensively used in the past two decades for the study of intracranial aneurysms (IAs), a dangerous disease that occurs in the arteries that reach the brain. They may affect up to 10 % of the world's…
Mechanics has an important role during morphogenesis, both in the generation of forces driving cell shape changes and in determining the effective material properties of cells and tissues. Drosophila dorsal closure (DC) has emerged as a…
Living soft tissues appear to promote the development and maintenance of a preferred mechanical state within a defined tolerance around a so-called set-point. This phenomenon is often referred to as mechanical homeostasis. In contradiction…
Osteoarthritis (OA) is a multifaceted joint disease which poses significant socioeconomic burdens and remains a significant clinical challenge. Evidence suggests that structural and mechanical changes in subchondral bone influence the…
Foam glass made from waste glass has high chemical and mechanical stability and flexible structural properties, making it suitable for a wide range of applications. To ensure its reliability, it is essential to understand its mechanical…
Living tissue is able to withstand large stresses in everyday life, yet it also actively adapts to dynamic loads. This remarkable mechanical behaviour emerges from the interplay between living cells and their non-living extracellular…
Objective: This study aims to evaluate the functional significance of coronary stenosis by analyzing low-level radiomic features of the pericoronary adipose tissue (PCAT) surrounding the lesions, which are indicative of its inflammation…