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The thermodynamics of proteins indicate that folding/unfolding takes place either through stable intermediates or through a two-state process without intermediates. The rather short folding times of the two-state process indicate that…

Condensed Matter · Physics 2016-08-31 Audun Bakk , Johan S. Hoye , Alex Hansen , Kim Sneppen , Mogens Hogh Jensen

Molecular motor proteins serve as an essential component of intracellular transport by generating forces to haul cargoes along cytoskeletal filaments. Two species of motors that are directed oppositely (e.g. kinesin, dynein) can be attached…

Subcellular Processes · Quantitative Biology 2017-05-10 Christopher E. Miles , James P. Keener

Nanofluidic transport is ubiquitous in natural systems from extra-cellular communication in biology to geological phenomena, and promotes the emergence of new technologies such as energy harvesting and water desalination. While experimental…

Soft Condensed Matter · Physics 2026-03-23 Aymeric Allemand , Anne-Laure Biance , Christophe Ybert , Laurent Joly

We generalize the fermionic renormalization group method to describe analytically transport through a double barrier structure in a one-dimensional system. Focusing on the case of weakly interacting electrons, we investigate thoroughly the…

Strongly Correlated Electrons · Physics 2009-11-07 D. G. Polyakov , I. V. Gornyi

Membrane transporters contribute to the regulation of the internal environment of cells by translocating substrates across cell membranes. Like all physical systems, the behaviour of membrane transporters is constrained by the laws of…

Biomolecules · Quantitative Biology 2023-07-19 Michael Pan , Peter J. Gawthrop , Kenneth Tran , Joseph Cursons , Edmund J. Crampin

We propose an alternative mechanism for intracellular cargo transport which results from motor induced longitudinal fluctuations of cytoskeletal microtubules (MT). The longitudinal fluctuations combined with transient cargo binding to the…

Soft Condensed Matter · Physics 2007-05-23 Igor M. Kulić , Philip C. Nelson

Catalytically active particles suspended in a liquid can move due to self-phoresis by generating solute gradients via chemical reactions of the solvent occurring at parts of their surface. Such particles can be used as carriers at the…

Soft Condensed Matter · Physics 2011-07-22 M. N. Popescu , M. Tasinkevych , S. Dietrich

Anomalously slow passive diffusion, $\langle \delta x^2(t)\rangle\simeq t^{\alpha}$, with $0<\alpha<1$, of larger tracers such as messenger RNA and endogenous submicron granules in the cytoplasm of living biological cells has been…

Biological Physics · Physics 2014-09-24 Igor Goychuk , Vasyl O. Kharchenko , Ralf Metzler

We explore electron transport properties for the model of benzene-1, 4-dithiolate (BDT) molecule and for some other geometric models of benzene molecule attached to two semi-infinite one-dimensional metallic electrodes using the Green's…

Mesoscale and Nanoscale Physics · Physics 2010-04-13 Santanu K. Maiti

Depinning and nonequilibrium transitions within sliding states in systems driven over quenched disorder arise across a wide spectrum of size scales ranging from atomic friction at the nanoscale, flux motion in type-II superconductors at the…

Soft Condensed Matter · Physics 2017-03-22 Cs. Sándor , A. Libál , C. Reichhardt , C. J. Olson Reichhardt

Electron transmission through molecules and molecular interfaces has been a subject of intensive research due to recent interest in electron transfer phenomena underlying the operation of the scanning tunneling microscope (STM) on one hand,…

Condensed Matter · Physics 2015-06-24 Abraham Nitzan

Weakly coupled molecular junctions are an active and important field of research as they exhibit various non-linear transport phenomena. We have investigated the carrier transport through weakly coupled B2C2N2H6 molecules using quantum…

Mesoscale and Nanoscale Physics · Physics 2020-03-09 Dibyajyoti Ghosh , Prakash Parida , Swapan K. Pati

Eukaryotic cells and intracellular pathogens such as bacteria or viruses utilize the actin polymerization machinery to propel themselves forward. Thereby, the onset of motion and choice of direction may be the result of a spontaneous…

Soft Condensed Matter · Physics 2009-09-04 Karin John , Denis Caillerie , Philippe Peyla , Mourad Ismail , Annie Raoult , Jacques Prost

We investigate energy transport in several two-level atom or spin-1/2 models by a direct coupling to heat baths of different temperatures. The analysis is carried out on the basis of a recently derived quantum master equation which…

Quantum Physics · Physics 2009-11-13 Mathias Michel , Ortwin Hess , Hannu Wichterich , Jochen Gemmer

The folding dynamics of small single-domain proteins is a current focus of simulations and experiments. Many of these proteins are 'two-state folders', i.e. proteins that fold rather directly from the denatured state to the native state,…

Biomolecules · Quantitative Biology 2020-01-08 Thomas R. Weikl

Ionic transport in nanopores is a fundamentally and technologically important problem in view of its occurrence in biological processes and its impact on novel DNA sequencing applications. Using microscopic calculations, here we show that…

Soft Condensed Matter · Physics 2009-09-26 Michael Zwolak , Johan Lagerqvist , Massimiliano Di Ventra

We developed the theory of elastic electron tunneling through a potential barrier driven by a strong high-frequency electromagnetic field. It is demonstrated that the driven barrier can be considered as a stationary two-barrier potential…

Mesoscale and Nanoscale Physics · Physics 2023-11-13 M. V. Boev , V. M. Kovalev , O. V. Kibis

Many natural and industrial processes rely on constrained transport, such as proteins moving through cells, particles confined in nanocomposite materials or gels, individuals in highly dense collec- tives and vehicular traffic conditions.…

We study a two filament driven lattice gas model with oppositely directed species of particles moving on two parallel filaments with filament switching processes and particle inflow and outflow at filament ends. The filament switching…

Soft Condensed Matter · Physics 2017-03-08 Subhadip Ghosh , Ignacio Pagonabarraga , Sudipto Muhuri

The cell cytoskeleton is a striking example of "active" medium driven out-of-equilibrium by ATP hydrolysis. Such activity has been shown recently to have a spectacular impact on the mechanical and rheological properties of the cellular…

Statistical Mechanics · Physics 2015-05-13 C. Loverdo , O. Benichou , M. Moreau , R. Voituriez