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Knowledge graphs, collectively as a knowledge network, have become critical tools for knowledge discovery in computable and explainable knowledge systems. Due to the semantic and structural complexities of biomedical data, these knowledge…

Other Quantitative Biology · Quantitative Biology 2025-09-29 Chunlei Wu , Hongfang Liu , Jason Flannick , Mark A. Musen , Andrew I. Su , Lawrence Hunter , Thomas M. Powers , Cathy H. Wu

In this paper we provide a comprehensive introduction to knowledge graphs, which have recently garnered significant attention from both industry and academia in scenarios that require exploiting diverse, dynamic, large-scale collections of…

The trends of open science have enabled several open scholarly datasets which include millions of papers and authors. Managing, exploring, and utilizing such large and complicated datasets effectively are challenging. In recent years, the…

Artificial Intelligence · Computer Science 2025-08-19 Hung Nghiep Tran , Atsuhiro Takasu

This paper describes an ongoing multi-scale visual analytics approach for exploring and analyzing biomedical knowledge at scale.We utilize global and local views, hierarchical and flow-based graph layouts, multi-faceted search, neighborhood…

Human-Computer Interaction · Computer Science 2021-10-22 Fahd Husain , Rosa Romero-Gomez , Emily Kuang , Dario Segura , Adamo Carolli , Lai Chung Liu , Manfred Cheung , Yohann Paris

In recent years, the size of big linked data has grown rapidly and this number is still rising. Big linked data and knowledge bases come from different domains such as life sciences, publications, media, social web, and so on. However, with…

Databases · Computer Science 2019-02-21 Feichen Shen

Knowledge graphs are an efficient method for representing and connecting information across various concepts, useful in reasoning, question answering, and knowledge base completion tasks. They organize data by linking points, enabling…

Artificial Intelligence · Computer Science 2025-02-25 Saher Mohamed , Kirollos Farah , Abdelrahman Lotfy , Kareem Rizk , Abdelrahman Saeed , Shahenda Mohamed , Ghada Khouriba , Tamer Arafa

Contextual information is widely considered for NLP and knowledge discovery in life sciences since it highly influences the exact meaning of natural language. The scientific challenge is not only to extract such context data, but also to…

Databases · Computer Science 2020-01-24 Jens Dörpinghaus , Andreas Stefan , Bruce Schultz , Marc Jacobs

Knowledge Graphs have been one of the fundamental methods for integrating heterogeneous data sources. Integrating heterogeneous data sources is crucial, especially in the biomedical domain, where central data-driven tasks such as drug…

Machine Learning · Computer Science 2020-12-22 Islam Akef Ebeid , Majdi Hassan , Tingyi Wanyan , Jack Roper , Abhik Seal , Ying Ding

Virtually every sector of society is experiencing a dramatic growth in the volume of unstructured textual data that is generated and published, from news and social media online interactions, through open access scholarly communications and…

Computation and Language · Computer Science 2026-03-30 Vanni Zavarella

Keyword-based searches are today's standard in digital libraries. Yet, complex retrieval scenarios like in scientific knowledge bases, need more sophisticated access paths. Although each document somewhat contributes to a domain's body of…

Information Retrieval · Computer Science 2024-12-23 Hermann Kroll , Pascal Sackhoff , Timo Breuer , Ralf Schenkel , Wolf-Tilo Balke

Knowledge Graph Completion has been increasingly adopted as a useful method for helping address several tasks in biomedical research, such as drug repurposing or drug-target identification. To that end, a variety of datasets and Knowledge…

Machine Learning · Computer Science 2025-11-07 Alberto Cattaneo , Stephen Bonner , Thomas Martynec , Edward Morrissey , Carlo Luschi , Ian P Barrett , Daniel Justus

We introduce an approach to discovery informatics that uses so called knowledge graphs as the essential representation structure. Knowledge graph is an umbrella term that subsumes various approaches to tractable representation of large…

Artificial Intelligence · Computer Science 2015-04-29 Vit Novacek

With the rapid development of biomedical software and hardware, a large amount of relational data interlinking genes, proteins, chemical components, drugs, diseases, and symptoms has been collected for modern biomedical research. Many…

Artificial Intelligence · Computer Science 2021-01-21 Yankai Chen , Yaozu Wu , Shicheng Ma , Irwin King

Recognizing similarities among entities is central to both human cognition and computational intelligence. Within this broader landscape, Entity Set Expansion is one prominent task aimed at taking an initial set of (tuples of) entities and…

Artificial Intelligence · Computer Science 2026-01-08 Giovanni Amendola , Pietro Cofone , Marco Manna , Aldo Ricioppo

Background : Knowledge is evolving over time, often as a result of new discoveries or changes in the adopted methods of reasoning. Also, new facts or evidence may become available, leading to new understandings of complex phenomena. This is…

Computation and Language · Computer Science 2023-04-24 Ayoub Harnoune , Maryem Rhanoui , Mounia Mikram , Siham Yousfi , Zineb Elkaimbillah , Bouchra El Asri

We present a new unified graph-based representation of medical data, combining genetic information and medical records of patients with medical knowledge via a unique knowledge graph. This approach allows us to infer meaningful information…

Artificial Intelligence · Computer Science 2024-10-22 Davide Belluomo , Tiziana Calamoneri , Giacomo Paesani , Ivano Salvo

Discovery gene-disease links is important in biology and medicine areas, enabling disease identification and drug repurposing. Machine learning approaches accelerate this process by leveraging biological knowledge represented in ontologies…

Machine Learning · Computer Science 2025-04-14 Catarina Canastra , Cátia Pesquita

Identifying relationships between concepts is a key aspect of scientific knowledge synthesis. Finding these links often requires a researcher to laboriously search through scien- tific papers and databases, as the size of these resources…

Computation and Language · Computer Science 2016-02-12 Stephanie L. Hyland , Theofanis Karaletsos , Gunnar Rätsch

In recent years, following FAIR and open data principles, the number of available big data including biomedical data has been increased exponentially. In order to extract knowledge, these data should be curated, integrated, and semantically…

Databases · Computer Science 2018-11-06 Samaneh Jozashoori , Tatiana Novikova , Maria-Esther Vidal

Motivation: Biological data and knowledge bases increasingly rely on Semantic Web technologies and the use of knowledge graphs for data integration, retrieval and federated queries. In the past years, feature learning methods that are…

Quantitative Methods · Quantitative Biology 2017-05-01 Mona Alshahrani , Mohammed Asif Khan , Omar Maddouri , Akira R Kinjo , Núria Queralt-Rosinach , Robert Hoehndorf
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