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Coronary artery calcification (CAC) is a strong predictor of cardiovascular events, with CT-based Agatston scoring widely regarded as the clinical gold standard. However, CT is costly and impractical for large-scale screening, while chest…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Dylan Saeed , Ramtin Gharleghi , Susann Beier , Sonit Singh

We propose a fully automated algorithm based on a deep learning framework enabling screening of a coronary computed tomography angiography (CCTA) examination for confident detection of the presence or absence of coronary artery…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Sema Candemir , Richard D. White , Mutlu Demirer , Vikash Gupta , Matthew T. Bigelow , Luciano M. Prevedello , Barbaros S. Erdal

Automatic detection and classification of Cardiovascular disease (CVD) from Computed Tomography (CT) images play an important part in facilitating better-informed clinical decisions. However, most of the recent deep learning based methods…

Image and Video Processing · Electrical Eng. & Systems 2026-05-07 Ajay Mittal , Raghav Mehta , Omar Todd , Philipp Seeböck , Georg Langs , Ben Glocker

Coronary artery calcification (CAC) is a strong and independent predictor of cardiovascular disease (CVD). However, manual assessment of CAC often requires radiological expertise, time, and invasive imaging techniques. The purpose of this…

Computer Vision and Pattern Recognition · Computer Science 2024-02-16 Andrew M. Nguyen , Jianfei Liu , Tejas Sudharshan Mathai , Peter C. Grayson , Ronald M. Summers

Precise localization of coronary arteries in Computed Tomography (CT) scans is critical from the perspective of medical assessment of coronary artery disease. Although various methods exist that offer high-quality segmentation of coronary…

Image and Video Processing · Electrical Eng. & Systems 2024-10-27 Mariusz Bujny , Katarzyna Jesionek , Jakub Nalepa , Karol Miszalski-Jamka , Katarzyna Widawka-Żak , Sabina Wolny , Marcin Kostur

In patients with coronary artery stenoses of intermediate severity, the functional significance needs to be determined. Fractional flow reserve (FFR) measurement, performed during invasive coronary angiography (ICA), is most often used in…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Majd Zreik , Nikolas Lessmann , Robbert W. van Hamersvelt , Jelmer M. Wolterink , Michiel Voskuil , Max A. Viergever , Tim Leiner , Ivana Išgum

The analysis of carotid arteries, particularly plaques, in multi-sequence Magnetic Resonance Imaging (MRI) data is crucial for assessing the risk of atherosclerosis and ischemic stroke. In order to evaluate metrics and radiomic features,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Marie-Christine Pali , Christina Schwaiger , Malik Galijasevic , Valentin K. Ladenhauf , Stephanie Mangesius , Elke R. Gizewski

Non-invasive detection of cardiovascular disorders from radiology scans requires quantitative image analysis of the heart and its substructures. There are well-established measurements that radiologists use for diseases assessment such as…

Machine Learning · Statistics 2017-08-04 Aliasghar Mortazi , Jeremy Burt , Ulas Bagci

Coronary artery disease (CAD) is a leading cause of cardiovascular-related mortality, and accurate stenosis detection is crucial for effective clinical decision-making. Coronary angiography remains the gold standard for diagnosing CAD, but…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Baixiang Huang , Yu Luo , Guangyu Wei , Songyan He , Yushuang Shao , Xueying Zeng

Coronary artery calcium (CAC) is a significant marker of atherosclerosis and cardiovascular events. In this work we present a system for the automatic quantification of calcium score in ECG-triggered non-contrast enhanced cardiac computed…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 G. Santini , D. Della Latta , N. Martini , G. Valvano , A. Gori , A. Ripoli , C. L. Susini , L. Landini , D. Chiappino

Coronary artery calcification (CAC) is a strong predictor of cardiovascular risk but remains underutilized in clinical routine thoracic imaging due to the need for dedicated imaging protocols and manual annotation. We present DeepCAC2, a…

Image and Video Processing · Electrical Eng. & Systems 2026-03-27 Leonard Nürnberg , Simon Bernatz , Borek Foldyna , Michael T. Lu , Andrey Fedorov , Hugo JWL Aerts

Automatic labelling of anatomical structures, such as coronary arteries, is critical for diagnosis, yet existing (non-deep learning) methods are limited by a reliance on prior topological knowledge of the expected tree-like structures. As…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Yadan Li , Mohammad Ali Armin , Simon Denman , David Ahmedt-Aristizabal

Detection of non-calcified plaques in the coronary tree is a challenging problem due to the nature of comprising substances. Hard plaques are easily discernible in CTA data cloud due to apparent bright behaviour, therefore many approaches…

Computer Vision and Pattern Recognition · Computer Science 2016-08-02 Muhammad Moazzam Jawaid

Computed Tomography Coronary Angiography (CTCA) is a non-invasive method to evaluate coronary artery anatomy and disease. CTCA is ideal for geometry reconstruction to create virtual models of coronary arteries. To our knowledge there is no…

Computer Vision and Pattern Recognition · Computer Science 2022-11-04 Ramtin Gharleghi , Dona Adikari , Katy Ellenberger , Mark Webster , Chris Ellis , Arcot Sowmya , Sze-Yuan Ooi , Susann Beier

Early detection and diagnosis of coronary artery disease (CAD) could save lives and reduce healthcare costs. The current clinical practice is to perform CAD diagnosis through analysing medical images from computed tomography coronary…

Coronary angiography is the main tool for assessing coronary artery disease, but visual grading of stenosis is variable and only moderately related to ischaemia. Wire based fractional flow reserve (FFR) improves lesion selection but is not…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Georgy Kopanitsa , Oleg Metsker , Alexey Yakovlev

Acute Coronary Syndrome (ACS) is a syndrome caused by a decrease in blood flow in the coronary arteries. The ACS is usually related to coronary thrombosis and is primarily caused by plaque rupture followed by plaque erosion and calcified…

Computer Vision and Pattern Recognition · Computer Science 2020-05-22 Tae Joon Jun , Soo-Jin Kang , June-Goo Lee , Jihoon Kweon , Wonjun Na , Daeyoun Kang , Dohyeun Kim , Daeyoung Kim , Young-Hak Kim

The traditional interpretation of Intravascular Ultrasound (IVUS) images during Percutaneous Coronary Intervention (PCI) is time-intensive and inconsistent, relying heavily on physician expertise. Regulatory restrictions and privacy…

Image and Video Processing · Electrical Eng. & Systems 2024-12-23 Chiu-Han Hsiao , Kai Chen , Tsung-Yu Peng , Wei-Chieh Huang

More than 13 million people suffer from ischemic cerebral stroke worldwide each year. Thrombolytic treatment can reduce brain damage but has a narrow treatment window. Computed Tomography Perfusion imaging is a commonly used primary…

Image and Video Processing · Electrical Eng. & Systems 2021-04-22 Luca Tomasetti , Kjersti Engan , Mahdieh Khanmohammadi , Kathinka Dæhli Kurz

Heavy smokers undergoing screening with low-dose chest CT are affected by cardiovascular disease as much as by lung cancer. Low-dose chest CT scans acquired in screening enable quantification of atherosclerotic calcifications and thus…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Nikolas Lessmann , Bram van Ginneken , Majd Zreik , Pim A. de Jong , Bob D. de Vos , Max A. Viergever , Ivana Išgum