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Epilepsy is one of the most prevalent brain disorders that disrupts the lives of millions worldwide. For patients with drug-resistant seizures, there exist implantable devices capable of monitoring neural activity, promptly triggering…

Signal Processing · Electrical Eng. & Systems 2023-10-31 Arman Zarei , Bingzhao Zhu , Mahsa Shoaran

Reliable seizure detection from electroencephalography (EEG) time series is a high-priority clinical goal, yet the acquisition cost and scarcity of labeled EEG data limit the performance of machine learning methods. This challenge is…

Methodology · Statistics 2026-01-30 Nina Moutonnet , Joshua Corneck , Felipe Tobar , Danilo Mandic

Introduction: Approximately 23 million or 30% of epilepsy patients worldwide suffer from drug-resistant epilepsy (DRE). The unpredictability of seizure occurrences, which causes safety issues as well as social concerns, restrict the…

Machine Learning · Computer Science 2024-10-10 Shriya Jaddu , Sidh Jaddu , Camilo Gutierrez , Quincy K. Tran

Epileptic seizure forecasting, combined with the delivery of preventative therapies, holds the potential to greatly improve the quality of life for epilepsy patients and their caregivers. Forecasting seizures could prevent some potentially…

Signal Processing · Electrical Eng. & Systems 2020-05-18 Nhan Duy Truong , Yikai Yang , Christina Maher , Armin Nikpour , Omid Kavehei

Epilepsy, affecting approximately 50 million people globally, is characterized by abnormal brain activity and remains challenging to treat. The diagnosis of epilepsy relies heavily on electroencephalogram (EEG) data, where specialists…

We introduce the Divergence Phase Index (DPI), a novel framework for quantifying phase differences in one and multidimensional signals, grounded in harmonic analysis via the Riesz transform. Based on classical Hilbert Transform phase…

Machine Learning · Statistics 2025-10-07 Magaly Catanzariti , Hugo Aimar , Diego M. Mateos

Over the past decade, high-frequency oscillations (HFOs) have been studied as a promising biomarker for localizing epileptogenic areas in drug-resistant patients requiring pre-surgical intervention, while exploiting intracranial…

Signal Processing · Electrical Eng. & Systems 2024-12-24 Zayneb Sadek , Abir Hadriche , Rahma Maalej , Nawel Jmail

Prediction of epilepsy based on electroencephalogram (EEG) signals is a rapidly evolving field. Previous studies have traditionally applied 1D processing to the entire EEG signal. However, we have adopted the Gram Matrix method to transform…

Machine Learning · Computer Science 2025-12-16 Bihao You , Jiping Cui

Objective: The detection of epileptic seizures from scalp electroencephalogram (EEG) signals can facilitate early diagnosis and treatment. Previous studies suggested that the Gaussianity of EEG distributions changes depending on the…

Signal Processing · Electrical Eng. & Systems 2021-03-03 Akira Furui , Ryota Onishi , Akihito Takeuchi , Tomoyuki Akiyama , Toshio Tsuji

Understanding epistasis (genetic interaction) may shed some light on the genomic basis of common diseases, including disorders of maximum interest due to their high socioeconomic burden, like schizophrenia. Distance correlation is an…

Epilepsy affects more than 50 million people worldwide, making it one of the world's most prevalent neurological diseases. The main symptom of epilepsy is seizures, which occur abruptly and can cause serious injury or death. The ability to…

Signal Processing · Electrical Eng. & Systems 2024-02-06 Zakary Georgis-Yap , Milos R. Popovic , Shehroz S. Khan

Epileptic seizures are transient neurological events characterized by abnormal and excessive neuron activity in the brain, which are often associated with measurable disturbances in the cardiovascular system. Traditionally,…

Signal Processing · Electrical Eng. & Systems 2026-05-20 Mohammad Reza Chopannavaz , Foad Ghaderi

Epilepsy affects 50 million people worldwide and is one of the most common serious neurological disorders. Seizure detection and classification is a valuable tool for diagnosing and maintaining the condition. An automated classification…

Signal Processing · Electrical Eng. & Systems 2022-08-22 Scot Davidson , Niamh McCallan , Kok Yew Ng , Pardis Biglarbeigi , Dewar Finlay , Boon Leong Lan , James McLaughlin

Epilepsy is a neurological brain disorder which life threatening and gives rise to recurrent seizures that are unprovoked. It occurs due to the abnormal chemical changes in our brain. Over the course of many years, studies have been…

Signal Processing · Electrical Eng. & Systems 2022-10-13 Muhammad Shoaib Farooq , Aimen Zulfiqar , Shamyla Riaz

In recent years, machine learning has become an increasingly powerful tool for supporting seizure detection and monitoring in epilepsy care. Traditional approaches focus on identifying seizures only after they begin, which limits the…

Machine Learning · Computer Science 2025-10-30 Ria Jayanti , Tanish Jain

Electrophysiological observation plays a major role in epilepsy evaluation. However, human interpretation of brain signals is subjective and prone to misdiagnosis. Automating this process, especially seizure detection relying on scalp-based…

Machine Learning · Computer Science 2018-07-06 David Ahmedt-Aristizabal , Clinton Fookes , Kien Nguyen , Sridha Sridharan

Epilepsy is the most common neurological disorder and an accurate forecast of seizures would help to overcome the patient's uncertainty and helplessness. In this contribution, we present and discuss a novel methodology for the…

Epilepsy is a highly prevalent brain condition with many serious complications arising from it. The majority of patients which present to a clinic and undergo electroencephalogram (EEG) monitoring would be unlikely to experience seizures…

Signal Processing · Electrical Eng. & Systems 2023-12-14 Matthew McDougall , Hezam Albaqami , Ghulam Mubashar Hassan , Amitava Datta

The study aims to investigate the similarities and differences in the brain damage caused by Hypoxia-Ischemia (HI), Hypoglycemia, and Epilepsy. Hypoglycemia poses a significant challenge in improving glycemic regulation for insulin-treated…

Timely diagnosis is important for saving the life of epileptic patients. In past few years, a lot of treatments are available for epilepsy. These treatments require use of anti-seizure drugs but are not effective in controlling frequency of…

Machine Learning · Computer Science 2021-11-08 Shivam Gupta , Jyoti Meena , O. P Gupta