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Sickle Cell Disease (SCD) is a chronic genetic disorder characterized by recurrent acute painful episodes. Opioids are often used to manage these painful episodes; the extent of their use in managing pain in this disorder is an issue of…

Skin cancer is a major public health problem around the world. Its early detection is very important to increase patient prognostics. However, the lack of qualified professionals and medical instruments are significant issues in this field.…

Single-cell RNA-sequencing (scRNA-seq) has become a routinely used technique to quantify the gene expression profile of thousands of single cells simultaneously. Analysis of scRNA-seq data plays an important role in the study of cell states…

The accurate segmentation and tracking of cells in microscopy image sequences is an important task in biomedical research, e.g., for studying the development of tissues, organs or entire organisms. However, the segmentation of touching…

Diabetic Retinopathy (DR) stands as the leading cause of blindness globally, particularly affecting individuals between the ages of 20 and 70. This paper presents a Computer-Aided Diagnosis (CAD) system designed for the automatic…

The swift advancement of single-cell RNA sequencing (scRNA-seq) technologies enables the investigation of cellular-level tissue heterogeneity. Cell annotation significantly contributes to the extensive downstream analysis of scRNA-seq data.…

Objectives. Sustainable management of plant diseases is an open challenge which has relevant economic and environmental impact. Optimal strategies rely on human expertise for field scouting under favourable conditions to assess the current…

This paper addresses the problem of few-shot skin disease classification by introducing a novel approach called the Sub-Cluster-Aware Network (SCAN) that enhances accuracy in diagnosing rare skin diseases. The key insight motivating the…

Mohs micrographic surgery (MMS) is the gold standard technique for removing high risk nonmelanoma skin cancer however, intraoperative histopathological examination demands significant time, effort, and professionality. The objective of this…

X-ray computed tomography (CT) is a widely used imaging technique that provides detailed examinations into the internal structure of an object with synchrotron CT (SR-CT) enabling improved data quality by using higher energy, monochromatic…

Glaucoma is one of the primary causes of vision loss around the world, necessitating accurate and efficient detection methods. Traditional manual detection approaches have limitations in terms of cost, time, and subjectivity. Recent…

Deep learning empowers the mainstream medical image segmentation methods. Nevertheless current deep segmentation approaches are not capable of efficiently and effectively adapting and updating the trained models when new incremental…

Early diagnosis of cancer often allows for a more vast choice of therapy opportunities. After a cancer diagnosis, staging provides essential information about the extent of disease in the body and the expected response to a particular…

Inspection of tissues using a light microscope is the primary method of diagnosing many diseases, notably cancer. Highly multiplexed tissue imaging builds on this foundation, enabling the collection of up to 60 channels of molecular…

Respiratory auscultation is crucial for early detection of pediatric pneumonia, a condition that can quickly worsen without timely intervention. In areas with limited physician access, effective auscultation is challenging. We present a…

International Classification of Diseases(ICD) is an authoritative health care classification system of different diseases and conditions for clinical and management purposes. Considering the complicated and dedicated process to assign…

We systematically evaluate a Deep Learning (DL) method in a 3D medical image segmentation task. Our segmentation method is integrated into the radiosurgery treatment process and directly impacts the clinical workflow. With our method, we…

Accurate segmentation of 3-D cell nuclei in microscopy images is essential for the study of nuclear organization, gene expression, and cell morphodynamics. Current image segmentation methods are challenged by the complexity and variability…

The emergence of digital technologies such as smartphones in healthcare applications have demonstrated the possibility of developing rich, continuous, and objective measures of multiple sclerosis (MS) disability that can be administered…

Central Serous Retinopathy (CSR) or Central Serous Chorioretinopathy (CSC) is a significant disease that causes blindness and vision loss among millions of people worldwide. It transpires as a result of accumulation of watery fluids behind…