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Cellphones equipped with high-quality cameras and powerful CPUs as well as GPUs are widespread. This opens new prospects to use such existing computational and imaging resources to perform medical diagnosis in developing countries at a very…

The disparity in access to machine learning tools for medical imaging across different regions significantly limits the potential for universal healthcare innovation, particularly in remote areas. Our research addresses this issue by…

Machine Learning · Computer Science 2024-07-26 John Kalkhof , Amin Ranem , Anirban Mukhopadhyay

Sickle cell disease (SCD) is common across Sub-Saharan Africa. However, the investigation of SCD in this area has been significantly limited mainly due to the lack of research facilities and skilled personnel. Here, we present optical…

Sickle cell disease causes erythrocytes to become sickle-shaped, affecting their movement in the bloodstream and reducing oxygen delivery. It has a high global prevalence and places a significant burden on healthcare systems, especially in…

Machine Learning · Computer Science 2026-01-21 Yaima Paz Soto , Silena Herold Garcia , Ximo Gual-Arnau , Antoni Jaume-i-Capó , Manuel González-Hidalgo

This research introduces an innovative method for the early screening of cardiorespiratory diseases based on an acquisition protocol, which leverages commodity smartphone's Inertial Measurement Units (IMUs) and deep learning techniques. We…

Machine Learning · Computer Science 2024-08-29 Lorenzo Simone , Luca Miglior , Vincenzo Gervasi , Luca Moroni , Emanuele Vignali , Emanuele Gasparotti , Simona Celi

High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Jacob Hanimann , Daniel Siegismund , Mario Wieser , Stephan Steigele

Using optical speckle scanning microscopy [1], we demonstrate that clear images of multiple cells can be obtained through biological scattering tissue, with subcellular resolution and good image quality, as long as the size of the imaging…

Optics · Physics 2023-07-19 Xin Yang , Ye Pu , Demetri Psaltis

Malaria remains one of the most pressing public health concerns globally, causing significant morbidity and mortality, especially in sub-Saharan Africa. Rapid and accurate diagnosis is crucial for effective treatment and disease management.…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Saurabh Sawant , Anurag Singh

In this paper we discuss a new method for detecting leukemia in microscopic blood smear images using deep neural networks to diagnose leukemia early in blood. leukemia is considered one of the most dangerous mortality causes for a human…

Image and Video Processing · Electrical Eng. & Systems 2023-01-10 Abdelmageed Ahmed , Alaa Nagy , Ahmed Kamal , Daila Farghl

Early childhood caries (ECC) is the most common, yet preventable chronic disease in children under the age of 6. Treatments on severe ECC are extremely expensive and unaffordable for socioeconomically disadvantaged families. The…

Computer Vision and Pattern Recognition · Computer Science 2020-08-19 Yipeng Zhang , Haofu Liao , Jin Xiao , Nisreen Al Jallad , Oriana Ly-Mapes , Jiebo Luo

The segmentation of medical images is a fundamental step in automated clinical decision support systems. Existing medical image segmentation methods based on supervised deep learning, however, remain problematic because of their reliance on…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Euijoon Ahn , Dagan Feng , Jinman Kim

The automated analysis of microscopy images is a challenge in the context of single-cell tracking and quantification. This work has as goals the study of the performance of deep learning for segmenting microscopy images and the improvement…

Quantitative Methods · Quantitative Biology 2022-10-05 André O. Françani

Celiac disease prevalence and diagnosis have increased substantially in recent years. The current gold standard for celiac disease confirmation is visual examination of duodenal mucosal biopsies. An accurate computer-aided biopsy analysis…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Jason W. Wei , Jerry W. Wei , Christopher R. Jackson , Bing Ren , Arief A. Suriawinata , Saeed Hassanpour

Among the different types of skin cancer, melanoma is considered to be the deadliest and is difficult to treat at advanced stages. Detection of melanoma at earlier stages can lead to reduced mortality rates. Desktop-based computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2022-05-26 Upender Kalwa , Christopher Legner , Taejoon Kong , Santosh Pandey

Quantifying the number of molecules from fluorescence microscopy measurements is an important topic in cell biology and medical research. In this work, we present a consecutive algorithm for super-resolution (STED) scanning microscopy that…

Applications · Statistics 2023-10-03 Katharina Proksch , Frank Werner , Jan Keller-Findeisen , Haisen Ta , Axel Munk

Background: Extensive clinical evidence suggests that a preventive screening of coronary heart disease (CHD) at an earlier stage can greatly reduce the mortality rate. We use 64 two-dimensional speckle tracking echocardiography (2D-STE)…

Machine Learning · Statistics 2021-05-21 Jingyi Zhang , Huolan Zhu , Yongkai Chen , Chenguang Yang , Huimin Cheng , Yi Li , Wenxuan Zhong , Fang Wang

Automated in-vitro cell detection and counting have been a key theme for artificial and intelligent biological analysis such as biopsy, drug analysis and decease diagnosis. Along with the rapid development of microfluidics and lab-on-chip…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Tiancheng Xia , Richard Jiang , YongQing Fu , Nanlin Jin

Nowadays, smartphones are ubiquitous, and almost everyone owns one. At the same time, the rapid development of AI has spurred extensive research on applying deep learning techniques to image classification. However, due to the limited…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Huu-Phong Phan-Nguyen , Anh Dao , Tien-Huy Nguyen , Tuan Quang , Huu-Loc Tran , Tinh-Anh Nguyen-Nhu , Huy-Thach Pham , Quan Nguyen , Hoang M. Le , Quang-Vinh Dinh

We consider the problem of accurately identifying cell boundaries and labeling individual cells in confocal microscopy images, specifically, 3D image stacks of cells with tagged cell membranes. Precise identification of cell boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2019-09-06 Jiaxiang Jiang , Po-Yu Kao , Samuel A. Belteton , Daniel B. Szymanski , B. S. Manjunath

Identification of abnormalities in red blood cells (RBC) is key to diagnosing a range of medical conditions from anaemia to liver disease. Currently this is done manually, a time-consuming and subjective process. This paper presents an…

Computer Vision and Pattern Recognition · Computer Science 2021-06-02 Annika Wong , Nantheera Anantrasirichai , Thanarat H. Chalidabhongse , Duangdao Palasuwan , Attakorn Palasuwan , David Bull