English
Related papers

Related papers: Improving Neural Protein-Protein Interaction Extra…

200 papers

The characterization of drug-protein interactions is crucial in the high-throughput screening for drug discovery. The deep learning-based approaches have attracted attention because they can predict drug-protein interactions without…

Machine Learning · Computer Science 2020-12-22 QHwan Kim , Joon-Hyuk Ko , Sunghoon Kim , Nojun Park , Wonho Jhe

Retrieval-augmented question answering (QA) integrates external information and thereby increases the QA accuracy of reader models that lack domain knowledge. However, documents retrieved for closed domains require high expertise, so the…

Computation and Language · Computer Science 2025-06-30 Jeonghun Cho , Gary Geunbae Lee

We introduce a pioneering methodology for boosting large language models in the domain of protein representation learning. Our primary contribution lies in the refinement process for correlating the over-reliance on co-evolution knowledge,…

Artificial Intelligence · Computer Science 2024-12-05 Yaoyao Xu , Xinjian Zhao , Xiaozhuang Song , Benyou Wang , Tianshu Yu

Semantic Text Embedding is a fundamental NLP task that encodes textual content into vector representations, where proximity in the embedding space reflects semantic similarity. While existing embedding models excel at capturing general…

Computation and Language · Computer Science 2025-06-02 Yiqun Sun , Qiang Huang , Anthony K. H. Tung , Jun Yu

While attention mechanisms have been proven to be effective in many NLP tasks, majority of them are data-driven. We propose a novel knowledge-attention encoder which incorporates prior knowledge from external lexical resources into deep…

Computation and Language · Computer Science 2020-03-05 Pengfei Li , Kezhi Mao , Xuefeng Yang , Qi Li

Knowledge-enhanced pre-trained models for language representation have been shown to be more effective in knowledge base construction tasks (i.e.,~relation extraction) than language models such as BERT. These knowledge-enhanced language…

Computation and Language · Computer Science 2022-10-25 Jiacheng Li , Yannis Katsis , Tyler Baldwin , Ho-Cheol Kim , Andrew Bartko , Julian McAuley , Chun-Nan Hsu

Soft prompts have been recently proposed as a tool for adapting large frozen language models (LMs) to new tasks. In this work, we repurpose soft prompts to the task of injecting world knowledge into LMs. We introduce a method to train soft…

Computation and Language · Computer Science 2022-10-11 Cicero Nogueira dos Santos , Zhe Dong , Daniel Cer , John Nham , Siamak Shakeri , Jianmo Ni , Yun-hsuan Sung

Word embeddings have been found to capture a surprisingly rich amount of syntactic and semantic knowledge. However, it is not yet sufficiently well-understood how the relational knowledge that is implicitly encoded in word embeddings can be…

Artificial Intelligence · Computer Science 2017-08-22 Zied Bouraoui , Shoaib Jameel , Steven Schockaert

In recent years, protein-text models have gained significant attention for their potential in protein generation and understanding. Current approaches focus on integrating protein-related knowledge into large language models through…

Computation and Language · Computer Science 2025-11-11 Juntong Wu , Zijing Liu , He Cao , Hao Li , Bin Feng , Zishan Shu , Ke Yu , Li Yuan , Yu Li

Incorporating factual knowledge into pre-trained language models (PLM) such as BERT is an emerging trend in recent NLP studies. However, most of the existing methods combine the external knowledge integration module with a modified…

Computation and Language · Computer Science 2022-05-06 Yinquan Lu , Haonan Lu , Guirong Fu , Qun Liu

Large language models (LLMs) have demonstrated impressive impact in the field of natural language processing, but they still struggle with several issues regarding, such as completeness, timeliness, faithfulness and adaptability. While…

Computation and Language · Computer Science 2023-08-24 Xintao Wang , Qianwen Yang , Yongting Qiu , Jiaqing Liang , Qianyu He , Zhouhong Gu , Yanghua Xiao , Wei Wang

Knowledge-enhanced Pre-trained Language Model (PLM) has recently received significant attention, which aims to incorporate factual knowledge into PLMs. However, most existing methods modify the internal structures of fixed types of PLMs by…

Computation and Language · Computer Science 2022-10-18 Jianing Wang , Wenkang Huang , Qiuhui Shi , Hongbin Wang , Minghui Qiu , Xiang Li , Ming Gao

Knowledge Graphs (KGs) provide a structured representation of knowledge but often suffer from challenges of incompleteness. To address this, link prediction or knowledge graph completion (KGC) aims to infer missing new facts based on…

Machine Learning · Computer Science 2025-01-03 Wenkai Tu , Guojia Wan , Zhengchun Shang , Bo Du

This paper proposes SR-KI, a novel approach for integrating real-time and large-scale structured knowledge bases (KBs) into large language models (LLMs). SR-KI begins by encoding KBs into key-value pairs using a pretrained encoder, and…

Computation and Language · Computer Science 2025-11-11 Bohan Yu , Wei Huang , Kang Liu

Reasoning about implied relationships (e.g., paraphrastic, common sense, encyclopedic) between pairs of words is crucial for many cross-sentence inference problems. This paper proposes new methods for learning and using embeddings of word…

Computation and Language · Computer Science 2019-04-09 Mandar Joshi , Eunsol Choi , Omer Levy , Daniel S. Weld , Luke Zettlemoyer

Investigating better ways to reuse the released pre-trained language models (PLMs) can significantly reduce the computational cost and the potential environmental side-effects. This paper explores a novel PLM reuse paradigm, Knowledge…

Computation and Language · Computer Science 2022-10-12 Lei Li , Yankai Lin , Xuancheng Ren , Guangxiang Zhao , Peng Li , Jie Zhou , Xu Sun

Understanding the 3D structures of protein multimers is crucial, as they play a vital role in regulating various cellular processes. It has been empirically confirmed that the multimer structure prediction~(MSP) can be well handled in a…

Computational Engineering, Finance, and Science · Computer Science 2024-03-01 Ziqi Gao , Xiangguo Sun , Zijing Liu , Yu Li , Hong Cheng , Jia Li

The limits of applicability of vision-and-language models are defined by the coverage of their training data. Tasks like vision question answering (VQA) often require commonsense and factual information beyond what can be learned from…

Computer Vision and Pattern Recognition · Computer Science 2021-01-18 Violetta Shevchenko , Damien Teney , Anthony Dick , Anton van den Hengel

Relation extraction has been widely studied to extract new relational facts from open corpus. Previous relation extraction methods are faced with the problem of wrong labels and noisy data, which substantially decrease the performance of…

Information Retrieval · Computer Science 2018-05-01 Dongdong Yang , Senzhang Wang , Zhoujun Li

High-throughput protein interaction detection methods are strongly affected by false positive and false negative results. Focused experiments are needed to complement the large-scale methods by validating previously detected interactions…

Molecular Networks · Quantitative Biology 2007-05-23 Istvan Albert , Reka Albert