Related papers: Precision of flow sensing by self-communicating ce…
Patient-specific therapies require that cells be manufactured in multiple batches of small volumes, making it a challenge for conventional modes of quality control. The added complexity of inherent variability (even within batches)…
Cellular decision-making based on information received from the external environment is frequently initiated by transmembrane receptors. These receptors are known to propagate such information by triggering a series of irreversible,…
Flow cytometry is a widespread and powerful technique, whose resolution is determined by its capacity to accurately distinguish fluorescently positive populations from negative ones. However, most informative results are discarded while…
High throughput real-time instruments are needed to acquire large data sets for detection and classification of rare events. Enabled by the photonic time stretch digitizer, a new class of instruments with record throughputs have led to the…
The effects of cell size and deformability on the lateral migration and deformation of living cells flowing through a rectangular microchannel has been numerically investigated and compared with the inertial-microfluidics data on detection…
Recent studies have highlighted intracellular viscosity as a key biomechanical property with potential as a biomarker for cancer cell metastasis. In the context of cellular mechanobiology, magnetic rotational spectroscopy (MRS), which…
Meridional circulation regulates the Sun's interior dynamics and magnetism. While it is well accepted that meridional flows are poleward at the Sun's surface, helioseismic observations have yet to provide a definitive answer for the depth…
By measuring the transmission of near-resonant light through an atomic vapor confined in a nano-cell we demonstrate a mesoscopic optical response arising from the non-locality induced by the motion of atoms with a phase coherence length…
In contexts ranging from embryonic development to bacterial ecology, cell populations migrate chemotactically along self-generated chemical gradients, often forming a propagating front. Here, we theoretically show that the stability of such…
In digital pathology, both detection and classification of cells are important for automatic diagnostic and prognostic tasks. Classifying cells into subtypes, such as tumor cells, lymphocytes or stromal cells is particularly challenging.…
We address binary optical communication channels based on phase-shift keyed coherent signals in the presence of phase diffusion. We prove theoretically and demonstrate experimentally that a discrimination strategy based on homodyne…
This paper discusses the role of Transfer Learning (TL) and transformers in cancer detection based on image analysis. With the enormous evolution of cancer patients, the identification of cancer cells in a patient's body has emerged as a…
Establishing dense correspondences between a pair of images is an important and general problem. However, dense flow estimation is often inaccurate in the case of large displacements or homogeneous regions. For most applications and…
Understanding how biomechanical reorganization governs key biological processes, such as morphogenesis and development, requires predictive insights into stress distributions and cellular behavior. While traditional approaches focused on…
Flux of rigid or soft particles (such as drops, vesicles, red blood cells, etc.) in a channel is a complex function of particle concentration, which depends on the details of induced dissipation and suspension structure due to hydrodynamic…
Accelerating imaging speed in optical microscopy is often realized at the expense of image contrast, image resolution, and detection sensitivity- a common predicament for advancing high-speed and high-throughput cellular imaging. We here…
In a diffusion-based molecular communication system, molecules are employed to convey information. When propagation and reception processes are considered in a framework of first passage processes, we need to focus on absorbing receivers.…
In this letter, we present anti-cancer drug delivery strategies using knowledges obtained from our recent studies. We have conducted inverse analyses of "density distributions of colloidal particles near a focused surface" and "pair…
The motility of eukaryotic cells is strongly influenced by their environment, with confined cells often developing qualitatively different motility patterns from those migrating on simple two-dimensional substrates. Recent experiments,…
In this paper, we consider bidirectional relaying between two diffusion-based molecular transceivers (bio-nodes). As opposed to existing literature, we incorporate the effect of direct diffusion links between the nodes and leverage it to…