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Cell division and death can be regulated by the mechanical forces within a tissue. We study the consequences for the stability and roughness of a propagating interface, by analysing a model of mechanically-regulated tissue growth in the…

Biological Physics · Physics 2018-12-12 John J. Williamson , Guillaume Salbreux

Metastatic tumors often invade healthy neighboring tissues by forming multicellular finger-like protrusions emerging from the cancer mass. To understand the mechanical context behind this phenomenon, we here develop a minimalist fluid model…

Biological Physics · Physics 2018-09-18 Michał Bogdan , Thierry Savin

Soft interfaces formed by lipid membranes are fundamental to living cells, synthetic cells, and membrane-based soft materials. However, a quantitative framework linking molecular organization with nonlinear interfacial mechanics remains…

Soft Condensed Matter · Physics 2026-01-27 Kazutoshi Masuda , Miho Yanagisawa

This contribution presents a diffuse framework for modeling cracks in heterogeneous media. Interfaces are depicted by static phase-fields. This concept allows the use of non-conforming meshes. Another phase-field is used to describe the…

Materials Science · Physics 2020-05-11 Arne Claus Hansen-Dörr , Franz Dammaß , René de Borst , Markus Kästner

In this paper, we develop a sharp interface tumor growth model to study the effect of the tumor microenvironment using a complex far-field geometry that mimics a heterogeneous distribution of vasculature. Together with different nutrient…

Numerical Analysis · Mathematics 2020-03-20 Min-Jhe Lu , Chun Liu , John Lowengrub , Shuwang Li

The turbulent/non-turbulent interface is analysed in a direct numerical simulation of a boundary layer in the range $Re_\theta=2800-6600$, with emphasis on the behaviour of the relatively large-scale fractal intermittent region. This…

Fluid Dynamics · Physics 2017-10-23 Guillem Borrell , Javier Jiménez

Understanding the interface dynamics in non-equilibrium quantum systems remains a challenge. We study the interface dynamics of strongly coupled immiscible binary superfluids by using holographic duality. The full nonlinear evolution of the…

Quantum Gases · Physics 2024-05-30 Yu-Ping An , Li Li , Chuan-Yin Xia , Hua-Bi Zeng

In this paper, we investigate the tumor instability by employing both analytical and numerical techniques to validate previous results and extend the analytical findings presented in a prior study by Feng et al 2023. Building upon the…

Analysis of PDEs · Mathematics 2024-01-11 Jian-Guo Liu , Thomas Witelski , Xiaoqian Xu , Jiaqi Zhang

Two-dimensional Stokes flow with injection and suction is investigated through a second-order, perturbative mode-coupling approach. We examine the time-dependent disturbance of an initially circular interface separating two viscous fluids,…

Fluid Dynamics · Physics 2020-10-08 Gabriel Dias Carvalho , Rodolfo Brandão , José A. Miranda

The construction of a network of cell-to-cell contacts makes it possible to characterize the patterns and spatial organisation of tissues. Such networks are highly dynamic, depending on the changes of the tissue architecture caused by cell…

Tissues and Organs · Quantitative Biology 2013-06-25 Attila Csikász-Nagy , Luis M. Escudero , Martial Guillaud , Sean Sedwards , Buzz Baum , Matteo Cavaliere

We study the dynamical behavior of a one dimensional interface interacting with a sticky unpenetrable substrate or wall. The interface is subject to two effects going in opposite directions. Contact between the interface and the substrate…

Probability · Mathematics 2020-07-20 Hubert Lacoin , Shangjie Yang

We study the non-steady relaxation of a driven one-dimensional elastic interface at the depinning transition by extensive numerical simulations concurrently implemented on graphics processing units (GPUs). We compute the time-dependent…

Statistical Mechanics · Physics 2013-06-03 Ezequiel E. Ferrero , Sebastián Bustingorry , Alejandro B. Kolton

We study pattern formation, fluctuations and scaling induced by a growth-promoting active walker on an otherwise static interface. Active particles on an interface define a simple model for energy consuming proteins embedded in the plasma…

Statistical Mechanics · Physics 2019-11-28 Prachi Bisht , Mustansir Barma

We propose a mathematical kinetic framework to investigate interactions between tumor cells and the immune system, focusing on the spatial dynamics of tumor progression and immune responses. We develop two kinetic models: one describes a…

Cell Behavior · Quantitative Biology 2026-02-24 Martina Conte , Romina Travaglini

Interfaces in two-dimensional systems exhibit unexpected complex dynamical behaviors, the dynamics of a border connecting a stripe pattern and a uniform state is studied. Numerical simulations of a prototype isotropic model, the subcritical…

Pattern Formation and Solitons · Physics 2008-06-05 Marcel G. Clerc , Daniel Escaff , Rene Rojas

This article presents a multi-physics methodology for the numerical simulation of physical systems that involve the non-linear interaction of multi-phase reactive fluids and elastoplastic solids, inducing high strain-rates and high…

Computational Physics · Physics 2021-06-04 Tim Wallis , Philip T. Barton , Nikolaos Nikiforakis

We investigate the convergence of solutions of a recently proposed diffuse interface/phase field model for cell blebbing by means of matched asymptotic expansions. It is a biological phenomenon that increasingly attracts attention by both…

Analysis of PDEs · Mathematics 2023-02-10 Philipp Nöldner , Martin Burger , Harald Garcke

The flow in a Hele-Shaw cell with a time-increasing gap poses a unique shrinking interface problem. When the upper plate of the cell is lifted perpendicularly at a prescribed speed, the exterior less viscous fluid penetrates the interior…

Fluid Dynamics · Physics 2021-01-20 Meng Zhao , Zahra Niroobakhsh , John Lowengrub , Shuwang Li

We use a lattice gas cellular automata model in the presence of random dynamic scattering sites and quenched disorder in the two-phase immiscible model with the aim of producing an interface dynamics similar to that observed in Hele-Shaw…

Fluid Dynamics · Physics 2015-08-06 R. M. Azevedo , R. R. Montenegro-Filho , M. D. Coutinho-Filho

A finite element method for the evolution of a two-phase membrane in a sharp interface formulation is introduced. The evolution equations are given as an $L^2$--gradient flow of an energy involving an elastic bending energy and a line…

Numerical Analysis · Mathematics 2019-11-01 John W. Barrett , Harald Garcke , Robert Nürnberg