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Biomedical queries often rely on a deep understanding of specialized knowledge such as gene regulatory mechanisms and pathological processes of diseases. They require detailed analysis of complex physiological processes and effective…

Computation and Language · Computer Science 2026-02-02 Congying Liu , Xingyuan Wei , Peipei Liu , Yiqing Shen , Yanxu Mao , Tiehan Cui

Publicly accessible benchmarks that allow for assessing and comparing model performances are important drivers of progress in artificial intelligence (AI). While recent advances in AI capabilities hold the potential to transform medical…

Artificial Intelligence · Computer Science 2022-12-26 Kathrin Blagec , Jakob Kraiger , Wolfgang Frühwirt , Matthias Samwald

This study systematically evaluates 27 frontier Large Language Models on eight biology benchmarks spanning molecular biology, genetics, cloning, virology, and biosecurity. Models from major AI developers released between November 2022 and…

Machine Learning · Computer Science 2025-05-23 Lennart Justen

Large language models (LLMs) have excelled in various natural language processing tasks, but challenges in interpretability and trustworthiness persist, limiting their use in high-stakes fields. Causal discovery offers a promising approach…

Artificial Intelligence · Computer Science 2024-06-10 Wei Zhou , Hong Huang , Guowen Zhang , Ruize Shi , Kehan Yin , Yuanyuan Lin , Bang Liu

Issue-commit links, as a type of software traceability links, play a vital role in various software development and maintenance tasks. However, they are typically deficient, as developers often forget or fail to create tags when making…

Software Engineering · Computer Science 2023-08-22 Chenyuan Zhang , Yanlin Wang , Zhao Wei , Yong Xu , Juhong Wang , Hui Li , Rongrong Ji

Predicting the performance and energy consumption of computing hardware is critical for many modern applications. This will inform procurement decisions, deployment decisions, and autonomic scaling. Existing approaches to understanding the…

Machine Learning · Computer Science 2023-02-28 Mehmet Cengiz , Matthew Forshaw , Amir Atapour-Abarghouei , Andrew Stephen McGough

Relation extraction in the biomedical domain is challenging due to the lack of labeled data and high annotation costs, needing domain experts. Distant supervision is commonly used to tackle the scarcity of annotated data by automatically…

Computation and Language · Computer Science 2022-09-14 Saadullah Amin , Pasquale Minervini , David Chang , Pontus Stenetorp , Günter Neumann

This paper presents our joint research efforts on big data benchmarking with several industrial partners. Considering the complexity, diversity, workload churns, and rapid evolution of big data systems, we take an incremental approach in…

Information Retrieval · Computer Science 2013-07-02 Wanling Gao , Yuqing Zhu , Zhen Jia , Chunjie Luo , Lei Wang , Zhiguo Li , Jianfeng Zhan , Yong Qi , Yongqiang He , Shiming Gong , Xiaona Li , Shujie Zhang , Bizhu Qiu

We review a recent trend in computational systems biology which aims at using pattern recognition algorithms to infer the structure of large-scale biological networks from heterogeneous genomic data. We present several strategies that have…

Quantitative Methods · Quantitative Biology 2008-09-22 Jean-Philippe Vert

The challenge of replicating research results has posed a significant impediment to the field of molecular biology. The advent of modern intelligent systems has led to notable progress in various domains. Consequently, we embarked on an…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Jieming Cui , Ziren Gong , Baoxiong Jia , Siyuan Huang , Zilong Zheng , Jianzhu Ma , Yixin Zhu

Groups with complex set intersection relations are a natural way to model a wide array of data, from the formation of social groups to the complex protein interactions which form the basis of biological life. One approach to representing…

Machine Learning · Computer Science 2025-01-15 Sepideh Maleki , Josh Vekhter , Keshav Pingali

Scientific progress is driven by the deliberate articulation of what remains unknown. This study investigates the ability of large language models (LLMs) to identify research knowledge gaps in the biomedical literature. We define two…

Computation and Language · Computer Science 2025-10-30 Nourah M Salem , Elizabeth White , Michael Bada , Lawrence Hunter

While links in simple networks describe pairwise interactions between nodes, it is necessary to incorporate hypernetworks for modeling complex systems with arbitrary-sized interactions. In this study, we focus on the hyperlink prediction…

Social and Information Networks · Computer Science 2021-11-17 Liming Pan , Hui-Juan Shang , Peiyan Li , Haixing Dai , Wei Wang , Lixin Tian

Health informatics research is characterized by diverse data modalities, rapid knowledge expansion, and the need to integrate insights across biomedical science, data analytics, and clinical practice. These characteristics make it…

Artificial Intelligence · Computer Science 2025-09-24 Yuxiao Cheng , Jinli Suo

The reproduction and replication of research results has become a major issue for a number of scientific disciplines. In computer science and related computational disciplines such as systems biology, the challenges closely revolve around…

Software Engineering · Computer Science 2017-07-31 Tom Crick , Benjamin A. Hall , Samin Ishtiaq

Obtaining standardized crowdsourced benchmark of computational methods is a major issue in data science communities. Dedicated frameworks enabling fair benchmarking in a unified environment are yet to be developed. Here we introduce…

Machine Learning · Computer Science 2022-06-28 Zhen Xu , Sergio Escalera , Isabelle Guyon , Adrien Pavão , Magali Richard , Wei-Wei Tu , Quanming Yao , Huan Zhao

Biomedical data is inherently multimodal, consisting of electronic health records, medical imaging, digital pathology, genome sequencing, wearable sensors, and more. The application of artificial intelligence tools to these multifaceted…

Machine Learning · Computer Science 2024-08-26 Shentong Mo , Paul Pu Liang

Accurate parsing of citations is necessary for machine-readable scholarly infrastructure. But, despite sustained interest in this problem, existing evaluation techniques are often not generalizable, based on synthetic data, or not publicly…

Digital Libraries · Computer Science 2026-03-27 Parth Sarin , Juan Pablo Alperin , Adam Buttrick , Dione Mentis

Biomarkers play a central role in medicine's gradual progress towards proactive, personalized precision diagnostics and interventions. However, finding biomarkers that provide very early indicators of a change in health status, for example…

Cross-view UAV geolocalization is fundamentally a challenging large-scale image retrieval task, aiming to determine the geographic coordinates of Unmanned Aerial Vehicle (UAV) queries by matching them against an extensive geo-tagged…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Bowen Liu , Pengyue Jia , Wanyu Wang , Derong Xu , Jiawei Cheng , Jiancheng Dong , Xiao Han , Zimo Zhao , Chao Zhang , Bowen Yu , Fangyu Hong , Xiangyu Zhao
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