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The two-dimensional nature of mammography makes estimation of the overall breast density challenging, and estimation of the true patient-specific radiation dose impossible. Digital breast tomosynthesis (DBT), a pseudo-3D technique, is now…
Breast X-ray CT imaging is being considered in screening as an extension to mammography. As a large fraction of the population will be exposed to radiation, low-dose imaging is essential. Iterative image reconstruction based on solving an…
X-ray computed tomography (CT) reconstructs cross-sectional images from projection data. However, ionizing X-ray radiation associated with CT scanning might induce cancer and genetic damage. Therefore, the reduction of radiation dose has…
Cone Beam CT plays an important role in many medical fields nowadays, but the potential of this imaging modality is hampered by lower image quality compared to the conventional CT. A lot of recent research has been directed towards…
Digital breast tomosynthesis (DBT) exams should utilize the lowest possible radiation dose while maintaining sufficiently good image quality for accurate medical diagnosis. In this work, we propose a convolution neural network (CNN) to…
Diffuse optical breast imaging utilizes near-infrared (NIR) light propagation through tissues to assess the optical properties of tissue for the identification of abnormal tissue. This optical imaging approach is sensitive, cost-effective,…
Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…
Deep learning based solutions are being succesfully implemented for a wide variety of applications. Most notably, clinical use-cases have gained an increased interest and have been the main driver behind some of the cutting-edge data-driven…
Model based iterative reconstruction (MBIR) algorithms for low-dose X-ray CT are computationally expensive. To address this problem, we recently proposed a deep convolutional neural network (CNN) for low-dose X-ray CT and won the second…
To address the issues of limited samples, time-consuming feature design, and low accuracy in detection and classification of breast cancer pathological images, a breast cancer image classification model algorithm combining deep learning and…
By acquiring two sets of tomographic measurements at distinct X-ray spectra, the dual-energy CT (DECT) enables quantitative material-specific imaging. However, the conventionally decomposed material basis images may encounter severe image…
Breast tumor segmentation provides accurate tumor boundary, and serves as a key step toward further cancer quantification. Although deep learning-based approaches have been proposed and achieved promising results, existing approaches have…
Image reconstruction from insufficient data is common in computed tomography (CT), e.g., image reconstruction from truncated data, limited-angle data and sparse-view data. Deep learning has achieved impressive results in this field.…
Model based iterative reconstruction (MBIR) algorithms for low-dose X-ray CT are computationally complex because of the repeated use of the forward and backward projection. Inspired by this success of deep learning in computer vision…
The mathematical problem for Electrical Impedance Tomography (EIT) is a highly nonlinear ill-posed inverse problem requiring carefully designed reconstruction procedures to ensure reliable image generation. D-bar methods are based on a…
Sparse-view cone-beam CT (CBCT) reconstruction is an important direction to reduce radiation dose and benefit clinical applications. Previous voxel-based generation methods represent the CT as discrete voxels, resulting in high memory…
Digital Breast Tomosynthesis is an X-ray imaging technique that allows a volumetric reconstruction of the breast, from a small number of low-dose two-dimensional projections. Although it is already used in clinical setting, enhancing the…
Recently, deep learning has been successfully applied to the single-image super-resolution (SISR) with remarkable performance. However, most existing methods focus on building a more complex network with a large number of layers, which can…
Dual-energy computed tomography (DECT) has been widely used in many applications that need material decomposition. Image-domain methods directly decompose material images from high- and low-energy attenuation images, and thus, are…
Low dose X-ray computed tomography (LDCT) is desirable for reduced patient dose. This work develops image reconstruction methods with deep learning (DL) regularization for LDCT. Our methods are based on unrolling of proximal…