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Here we describe an "information based exchange" model of brain function that ascribes to neocortex, basal ganglia, and thalamus distinct network functions. The model allows us to analyze whole brain system set point measures, such as the…

Neurons and Cognition · Quantitative Biology 2015-09-17 James Kozloski

Neural Cellular Automata (NCA) represent a powerful framework for modeling biological self-organization, extending classical rule-based systems with trainable, differentiable (or evolvable) update rules that capture the adaptive…

Artificial Intelligence · Computer Science 2025-09-16 Benedikt Hartl , Michael Levin , Léo Pio-Lopez

Bacteria are easily characterizable model organisms with an impressively complicated set of capabilities. Among their capabilities is quorum sensing, a detailed cell-cell signaling system that may have a common origin with eukaryotic…

Neurons and Cognition · Quantitative Biology 2017-09-14 Archana Ram , Andrew Lo

Neurons, as eukaryotic cells, have powerful internal computation capabilities. One neuron can have many distinct states, and brains can use this capability. Processes of neuron growth and maintenance use chemical signalling between cell…

Neurons and Cognition · Quantitative Biology 2025-12-10 Robert Worden

Non-Boolean computing based on emerging post-CMOS technologies can potentially pave the way for low-power neural computing platforms. However, existing work on such emerging neuromorphic architectures have either focused on solely mimicking…

Emerging Technologies · Computer Science 2016-11-15 Abhronil Sengupta , Yong Shim , Kaushik Roy

Encoding models are used for predicting brain activity in response to sensory stimuli with the objective of elucidating how sensory information is represented in the brain. Encoding models typically comprise a nonlinear transformation of…

Neurons and Cognition · Quantitative Biology 2017-03-13 Umut Güçlü , Marcel A. J. van Gerven

This article highlights specific features of biological neurons and their dendritic trees, whose adoption may help advance artificial neural networks used in various machine learning applications. Advancements could take the form of…

Neurons and Cognition · Quantitative Biology 2021-06-15 Spyridon Chavlis , Panayiota Poirazi

The response of adult human bone marrow stromal stem cells to surface topographies generated through femtosecond laser machining can be predicted by a deep neural network. The network is capable of predicting cell response to a…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 Benita S. Mackay , Matthew Praeger , James A. Grant-Jacob , Janos Kanczler , Robert W. Eason , Richard O. C. Oreffo , Ben Mills

Computational neuroscience relies on large-scale dynamical-systems models of neurons, with a vast amount of offline, pre-simulation, tuned parameters, with models often tied to their brain simulators. These fixed parameters lead to stiff…

Neurons and Cognition · Quantitative Biology 2025-12-25 Lennart P. L. Landsmeer , Mario Negrello , Said Hamdioui , Christos Strydis

Pathophysiolpgical modelling of brain systems from microscale to macroscale remains difficult in group comparisons partly because of the infeasibility of modelling the interactions of thousands of neurons at the scales involved. Here, to…

Neurons and Cognition · Quantitative Biology 2026-01-30 Kang You , Gary Green , Jian Zhang

Interacting biological systems at all organizational levels display emergent behavior. Modeling these systems is made challenging by the number and variety of biological components and interactions (from molecules in gene regulatory…

Molecular Networks · Quantitative Biology 2023-10-20 Jordan C. Rozum , Colin Campbell , Eli Newby , Fatemeh Sadat Fatemi Nasrollahi , Reka Albert

Artificial neural networks and computational neuroscience models have made tremendous progress, allowing computers to achieve impressive results in artificial intelligence (AI) applications, such as image recognition, natural language…

Neural and Evolutionary Computing · Computer Science 2019-11-05 Giacomo Indiveri , Yulia Sandamirskaya

One major challenge of neuroscience is finding interesting structures in a seemingly disorganized neural activity. Often these structures have computational implications that help to understand the functional role of a particular brain…

Neurons and Cognition · Quantitative Biology 2023-09-01 Srdjan Ostojic , Stefano Fusi

Living neural networks emerge through a process of growth and self-organization that begins with a single cell and results in a brain, an organized and functional computational device. Artificial neural networks, however, rely on…

Neural and Evolutionary Computing · Computer Science 2019-06-05 Guruprasad Raghavan , Matt Thomson

Understanding of how biological neural networks process information is one of the biggest open scientific questions of our time. Advances in machine learning and artificial neural networks have enabled the modeling of neuronal behavior, but…

Quantum Physics · Physics 2024-09-17 Vinicius Hernandes , Eliska Greplova

A central goal in neuroscience is to provide explanations for how animal nervous systems can generate actions and cognitive states such as consciousness while artificial intelligence (AI) and machine learning (ML) seek to provide models…

Neurons and Cognition · Quantitative Biology 2024-05-24 Catalin C. Mitelut

We report recent research on computing with biology-based neural network models by means of physics-based opto-electronic hardware. New technology provides opportunities for very-high-speed computation and uncovers problems obstructing the…

Neural and Evolutionary Computing · Computer Science 2010-06-09 A. Steven Younger , Emmett Redd

Understanding the complexity of biological neural networks like the human brain is one of the scientific challenges of our century. The organization of the brain can be described at different levels, ranging from small neural networks to…

Neurons and Cognition · Quantitative Biology 2018-05-23 Stefano De Blasi

Axons functionally link the somato-dendritic compartment to synaptic terminals. Structurally and functionally diverse, they accomplish a central role in determining the delays and reliability with which neuronal ensembles communicate. By…

Neurons and Cognition · Quantitative Biology 2019-05-07 Pepe Alcami , Ahmed El Hady

We describe N-body networks, a neural network architecture for learning the behavior and properties of complex many body physical systems. Our specific application is to learn atomic potential energy surfaces for use in molecular dynamics…

Machine Learning · Computer Science 2018-03-06 Risi Kondor