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Accurate segmentation of organs from abdominal CT scans is essential for clinical applications such as diagnosis, treatment planning, and patient monitoring. To handle challenges of heterogeneity in organ shapes, sizes, and complex…

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer in which the tumor-vascular involvement greatly affects the resectability and, thus, overall survival of patients. However, current prognostic prediction methods fail to…

Image and Video Processing · Electrical Eng. & Systems 2023-09-14 Hexin Dong , Jiawen Yao , Yuxing Tang , Mingze Yuan , Yingda Xia , Jian Zhou , Hong Lu , Jingren Zhou , Bin Dong , Le Lu , Li Zhang , Zaiyi Liu , Yu Shi , Ling Zhang

Accurate segmentation of long and thin tubular structures is required in a wide variety of areas such as biology, medicine, and remote sensing. The complex topology and geometry of such structures often pose significant technical…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Jiaxing Huang , Yanfeng Zhou , Yaoru Luo , Guole Liu , Heng Guo , Ge Yang

Background: Pancreatic cancer is one of the most aggressive cancers, with poor survival rates. Endoscopic ultrasound (EUS) is a key diagnostic modality, but its effectiveness is constrained by operator subjectivity. This study evaluates a…

Automatic organ segmentation is an important yet challenging problem for medical image analysis. The pancreas is an abdominal organ with very high anatomical variability. This inhibits previous segmentation methods from achieving high…

Computer Vision and Pattern Recognition · Computer Science 2015-06-23 Holger R. Roth , Le Lu , Amal Farag , Hoo-Chang Shin , Jiamin Liu , Evrim Turkbey , Ronald M. Summers

Pancreatic cancer is one of the deadliest types of cancer, with 25% of the diagnosed patients surviving for only one year and 6% of them for five. Computed tomography (CT) screening trials have played a key role in improving early detection…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Agapi Davradou

An accurate segmentation of the pancreas on CT is crucial to identify pancreatic pathologies and extract imaging-based biomarkers. However, prior research on pancreas segmentation has primarily focused on modifying the segmentation model…

Image and Video Processing · Electrical Eng. & Systems 2025-04-10 Anisa V. Prasad , Tejas Sudharshan Mathai , Pritam Mukherjee , Jianfei Liu , Ronald M. Summers

Cone-beam CT (CBCT)-based online adaptive radiotherapy calls for accurate auto-segmentation to reduce the time cost for physicians to edit contours. However, deep learning (DL)-based direct segmentation of CBCT images is a challenging task,…

Medical Physics · Physics 2023-02-22 Xiao Liang , Howard Morgan , Ti Bai , Michael Dohopolski , Dan Nguyen , Steve Jiang

Abdominal multi-organ segmentation in computed tomography (CT) is crucial for many clinical applications including disease detection and treatment planning. Deep learning methods have shown unprecedented performance in this perspective.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-29 Mingjin Chen , Yongkang He , Yongyi Lu

The performance of a computer-aided automated diagnosis system of lung cancer from Computed Tomography (CT) volumetric images greatly depends on the accurate detection and segmentation of tumor regions. In this paper, we present Recurrent…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Uday Kamal , Abdul Muntakim Rafi , Rakibul Hoque , Jonathan Wu , Md. Kamrul Hasan

Computed Tomography (CT) based precise prostate segmentation for treatment planning is challenging due to (1) the unclear boundary of the prostate derived from CT's poor soft tissue contrast and (2) the limitation of convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Chengyin Li , Yao Qiang , Rafi Ibn Sultan , Hassan Bagher-Ebadian , Prashant Khanduri , Indrin J. Chetty , Dongxiao Zhu

Accurate segmentation of topological tubular structures, such as blood vessels and roads, is crucial in various fields, ensuring accuracy and efficiency in downstream tasks. However, many factors complicate the task, including thin local…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Yaolei Qi , Yuting He , Xiaoming Qi , Yuan Zhang , Guanyu Yang

Automatic organ segmentation is an important prerequisite for many computer-aided diagnosis systems. The high anatomical variability of organs in the abdomen, such as the pancreas, prevents many segmentation methods from achieving high…

Computer Vision and Pattern Recognition · Computer Science 2015-09-17 Holger R. Roth , Amal Farag , Le Lu , Evrim B. Turkbey , Ronald M. Summers

Cell instance segmentation in fluorescence microscopy images is becoming essential for cancer dynamics and prognosis. Data extracted from cancer dynamics allows to understand and accurately model different metabolic processes such as…

Due to the fact that pancreas is an abdominal organ with very large variations in shape and size, automatic and accurate pancreas segmentation can be challenging for medical image analysis. In this work, we proposed a fully automated two…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Ningning Zhao , Nuo Tong , Dan Ruan , Ke Sheng

Computer-aided medical image segmentation has been applied widely in diagnosis and treatment to obtain clinically useful information of shapes and volumes of target organs and tissues. In the past several years, convolutional neural network…

Computer Vision and Pattern Recognition · Computer Science 2022-01-11 Yixuan Wu , Kuanlun Liao , Jintai Chen , Jinhong Wang , Danny Z. Chen , Honghao Gao , Jian Wu

Accurate segmentation of tubular structures in medical images, such as vessels and airway trees, is crucial for computer-aided diagnosis, radiotherapy, and surgical planning. However, significant challenges exist in algorithm design when…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Yi Huang , Ke Zhang , Wei Liu , Yuanyuan Wang , Vishal M. Patel , Le Lu , Xu Han , Dakai Jin , Ke Yan

Automatic abnormality detection in abdominal CT scans can help doctors improve the accuracy and efficiency in diagnosis. In this paper we aim at detecting pancreatic ductal adenocarcinoma (PDAC), the most common pancreatic cancer. Taking…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fengze Liu , Yuyin Zhou , Elliot Fishman , Alan Yuille

Automatic pancreas segmentation in radiology images, eg., computed tomography (CT) and magnetic resonance imaging (MRI), is frequently required by computer-aided screening, diagnosis, and quantitative assessment. Yet pancreas is a…

Computer Vision and Pattern Recognition · Computer Science 2018-04-02 Jinzheng Cai , Le Lu , Fuyong Xing , Lin Yang

Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Jiasen Zhang , Mingrui Yang , Weihong Guo , Brian A. Xavier , Michael Bolen , Xiaojuan Li