Related papers: Computational hemodynamics in arteries with the on…
The availability of digital twins for the cardiovascular system will enable insightful computational tools both for research and clinical practice. This, however, demands robust and well defined models and methods for the different steps…
Understanding the physics of blood is challenging due to its nature as a suspension of soft particles and the fact that typical problems involve different scales. This is valid also for numerical investigations. In fact, many computational…
Computer modeling can provide quantitative insight into cardiac fluid dynamics phenomena that are not evident from standard imaging tools. We propose a new approach to modeling left ventricle fluid dynamics based on an image-driven…
The immersed boundary (IB) method is a mathematical and numerical framework for problems of fluid-structure interaction, treating the particular case in which an elastic structure is immersed in a viscous incompressible fluid. The IB…
Blood vessel constriction is simulated with particle-based method using a molecular dynamics authoring software known as Molecular Workbench (WM). Blood flow and vessel wall, the only components considered in constructing a blood vessel,…
Background and Objective: The role of red blood cell dynamics is emphasised in certain cardiovascular diseases, and thus needs to be closely studied. A multiphase model of blood flow allows the resolution of locally varying density of red…
This paper worked towards modeling blood platelets. Blood platelets, also known as thrombocytes, play a key role in blood clotting which is a vital human function. Furthermore, the role of these entities in strokes, myocardial infarctions,…
In this paper, we focus on investigating the influence on hydrodynamic factors of different coupled computational models describing the interaction between an incompressible fluid and two symmetric elastic or poroelastic structures. The…
Coronary artery stenosis, characterized by the narrowing of the lumen, significantly affects blood flow and contributes to the progression of cardiovascular diseases. This study investigates the hemodynamics of coronary artery models with…
Modelling of mechanical behaviour of pre-stressed fibre-reinforced composites is considered in a geometrically exact setting. A general approach which includes two different reference configurations is employed: one configuration…
Three-dimensional cardiovascular fluid dynamics simulations typically require computation of several cardiac cycles before they reach a periodic solution, rendering them computationally expensive. Furthermore, there is currently no…
Pulmonary hypertension (PH), defined by a mean pulmonary arterial pressure (mPAP) $>$ 20 mmHg, is characterized by increased pulmonary vascular resistance and decreased pulmonary arterial compliance. There are few measurable biomarkers of…
Computer simulation of "virtual interventions" may inform optimal valve repair for a given patient prior to intervention. However, the paucity of noninvasive methods to determine in vivo mechanical parameters of valves limits the accuracy…
Abdominal aortic aneurysms (AAAs) are pathologic dilatations of the abdominal aorta posing a high fatality risk upon rupture. Studying AAA progression and rupture risk often involves in-silico blood flow modelling with computational fluid…
We propose a hemodynamic reduced-order model bridging macroscopic and meso-scopic blood flow circulation scales from arteries to capillaries. In silico tree like vascular geometries, mathematically described by graphs, are synthetically…
Microfluidic technology has emerged as a powerful tool for studying complex biological processes with enhanced precision and control. A microfluidic chip was designed to emulate human-like microvascular networks with precise control over…
Computer simulations of blood flow in patients with anomalous aortic origin of a coronary artery (AAOCA) have the promise to provide insight into this complex disease. They provide an in-silico experimental platform to explore possible…
Numerical simulations of real-world phenomena require a computational scheme and a computational domain. In the context of haemodynamics, the computational domain is the blood vessel network through which blood flows. Such networks contain…
The liver has a unique blood supply system and plays an important role in the human blood circulatory system. Thus, hemodynamic problems related to the liver serve as an important part in clinical diagnosis and treatment. Although…
Ventricular Fibrillation (VF) is a malignant cardiac arrhythmia and the leading cause of sudden cardiac death, characterized by disorganized, high-frequency ventricular activity that results in the rapid loss of coordinated pump function…