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Accurate and computationally-viable representations of clouds and turbulence are a long-standing challenge for climate model development. Traditional parameterizations that crudely but efficiently approximate these processes are a leading…

Atmospheric and Oceanic Physics · Physics 2024-01-05 Jerry Lin , Mohamed Aziz Bhouri , Tom Beucler , Sungduk Yu , Michael Pritchard

Machine learning (ML) methods are being used in almost every conceivable area of electronic structure theory and molecular simulation. In particular, ML has become firmly established in the construction of high-dimensional interatomic…

Chemical Physics · Physics 2021-06-22 Julia Westermayr , Michael Gastegger , Kristof T. Schütt , Reinhard J. Maurer

Machine learning (ML) has emerged into formidable force for identifying hidden but pertinent patterns within a given data set with the objective of subsequent generation of automated predictive behavior. In the recent years, it is safe to…

High-performance computing (HPC) is reshaping computational drug discovery by enabling large-scale, time-efficient molecular simulations. In this work, we explore HPC-driven pipelines for Alzheimer's disease drug discovery, focusing on…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-03 Paul Ruiz Alliata , Diana Rubaga , Daniel Kumlin , Alberto Puliga

The selection, development, or comparison of machine learning methods in data mining can be a difficult task based on the target problem and goals of a particular study. Numerous publicly available real-world and simulated benchmark…

Machine Learning · Computer Science 2017-03-03 Randal S. Olson , William La Cava , Patryk Orzechowski , Ryan J. Urbanowicz , Jason H. Moore

The increasing capabilities of Machine Learning (ML) models go hand in hand with an immense amount of data and computational power required for training. Therefore, training is usually outsourced into HPC facilities, where we have started…

Machine Learning · Computer Science 2025-01-28 Sabrina Herbst , Vincenzo De Maio , Ivona Brandic

Robust execution environments are important for addressing key challenges in quantum computing, such as application development, portability, and reproducibility, and help unlock the development of modular quantum programs, driving forward…

Quantum Physics · Physics 2025-09-26 Aleksander Wennersteen , Matthieu Moreau , Aurelien Nober , Mourad Beji

Typical design flows are hierarchical and rely on assembling many individual technology elements from standard cells to complete boards. Providers use compact models to provide simplified views of their products to their users. Designers…

Hardware Architecture · Computer Science 2021-04-23 Dan Alexandrescu , Aneesh Balakrishnan , Thomas Lange , Maximilien Glorieux

Machine Learning (ML) research has increased substantially in recent years, due to the success of predictive modeling across diverse application domains. However, well-known barriers exist when attempting to deploy ML models in high-stakes,…

Machine Learning · Computer Science 2024-09-19 Nathan Wolfrath , Joel Wolfrath , Hengrui Hu , Anjishnu Banerjee , Anai N. Kothari

The emergence of large language models (LLMs) has significantly transformed natural language processing (NLP), enabling more generalized models to perform various tasks with minimal training. However, traditional sentiment analysis methods,…

Computation and Language · Computer Science 2026-01-13 Keito Inoshita , Xiaokang Zhou , Akira Kawai

Amid the rapid advancements in large machine learning (ML) models, universities worldwide are investing substantial funds and efforts into GPU clusters. However, managing a shared GPU cluster poses a pyramid of challenges, from hardware…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-15 Kaiqiang Xu , Decang Sun , Hao Wang , Zhenghang Ren , Xinchen Wan , Xudong Liao , Zilong Wang , Junxue Zhang , Kai Chen

Data pre-processing is a fundamental component in any data-driven application. With the increasing complexity of data processing operations and volume of data, Cylon, a distributed dataframe system, is developed to facilitate data…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-01-02 Kaiying Shan , Niranda Perera , Damitha Lenadora , Tianle Zhong , Arup Sarker , Supun Kamburugamuve , Thejaka Amila Kanewela , Chathura Widanage , Geoffrey Fox

As ultracold atom experiments become highly controlled and scalable quantum simulators, they require sophisticated control over high-dimensional parameter spaces and generate increasingly complex measurement data that need to be analyzed…

Quantum Gases · Physics 2025-09-11 Henning Schlömer , Annabelle Bohrdt

Machine learning (ML) in healthcare presents numerous opportunities for enhancing patient care, population health, and healthcare providers' workflows. However, the real-world clinical and cost benefits remain limited due to challenges in…

Machine Learning · Computer Science 2024-02-09 Suraj Rajendran , Weishen Pan , Mert R. Sabuncu , Yong Chen , Jiayu Zhou , Fei Wang

The R package merlin performs flexible joint modelling of hierarchical multi-outcome data. Increasingly, multiple longitudinal biomarker measurements, possibly censored time-to-event outcomes and baseline characteristics are available.…

Computation · Statistics 2020-07-29 Emma C. Martin , Alessandro Gasparini , Michael J. Crowther

The rise of machine learning (ML) and its integration into software systems has drastically changed development practices. While software engineering traditionally focused on manually created code artifacts with dedicated processes and…

Software Engineering · Computer Science 2025-02-25 Yorick Sens , Henriette Knopp , Sven Peldszus , Thorsten Berger

Context: Classification of software requirements into different categories is a critically important task in requirements engineering (RE). Developing machine learning (ML) approaches for requirements classification has attracted great…

Software Engineering · Computer Science 2023-02-27 Manal Binkhonain , Liping Zhao

Machine learning (ML) components are being added to more and more critical and impactful software systems, but the software development process of real-world production systems from prototyped ML models remains challenging with additional…

Software Engineering · Computer Science 2024-05-07 Jie JW Wu

Software and hardware co-design and optimization of HPC systems has become intolerably complex, ad-hoc, time consuming and error prone due to enormous number of available design and optimization choices, complex interactions between all…

Software Engineering · Computer Science 2013-08-13 Grigori Fursin

Machine learning (ML) offers powerful methods for detecting and modeling associations often in data with large feature spaces and complex associations. Many useful tools/packages (e.g. scikit-learn) have been developed to make the various…

Machine Learning · Computer Science 2022-06-27 Ryan J. Urbanowicz , Robert Zhang , Yuhan Cui , Pranshu Suri