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The integration of machine learning (ML) is critical for industrial competitiveness, yet its adoption is frequently stalled by the prohibitive costs and operational disruptions of upgrading legacy systems. The financial and logistical…

Machine Learning · Computer Science 2026-03-12 Ashiqur Rahman , Hamed Alhoori

Merlin++ is a C++ charged-particle tracking library developed for the simulation and analysis of complex beam dynamics within high energy particle accelerators. Accurate simulation and analysis of particle dynamics is an essential part of…

Recent advances in both theory and methods have created opportunities to simulate biomolecular processes more efficiently using adaptive ensemble simulations. Ensemble-based simulations are used widely to compute a number of individual…

Computational Engineering, Finance, and Science · Computer Science 2020-09-14 Vivek Balasubramanian , Travis Jensen , Matteo Turilli , Peter Kasson , Michael Shirts , Shantenu Jha

Building effective machine learning (ML) workflows to address complex tasks is a primary focus of the Automatic ML (AutoML) community and a critical step toward achieving artificial general intelligence (AGI). Recently, the integration of…

Machine Learning · Computer Science 2024-12-30 Yang Gu , Hengyu You , Jian Cao , Muran Yu , Haoran Fan , Shiyou Qian

Nuclear materials are often demanded to function for extended time in extreme environments, including high radiation fluxes and transmutation, high temperature and temperature gradients, stresses, and corrosive coolants. They also have a…

Materials Science · Physics 2022-11-18 Dane Morgan , Ghanshyam Pilania , Adrien Couet , Blas P. Uberuaga , Cheng Sun , Ju Li

HPC systems used for research run a wide variety of software and workflows. This software is often written or modified by users to meet the needs of their research projects, and rarely is built with security in mind. In this paper we…

MERLIN is an accelerator physics library written in C++ which can be used for a range of accelerator tracking simulations, including collimation in hadron colliders. Recently MERLIN has been upgraded to provide a robust tool for HL-LHC…

Accelerator Physics · Physics 2019-03-21 Haroon Rafique , Robert B Appleby , Roger J Barlow , James G Molson , Sam Tygier , Alessandra Valloni

We introduce a machine-learning (ML) framework for high-throughput benchmarking of diverse representations of chemical systems against datasets of materials and molecules. The guiding principle underlying the benchmarking approach is to…

Machine Learning · Computer Science 2021-12-07 Carl Poelking , Felix A. Faber , Bingqing Cheng

Advancements in the implementation of quantum hardware have enabled the acquisition of data that are intractable for emulation with classical computers. The integration of classical machine learning (ML) algorithms with these data holds…

Quantum Physics · Physics 2025-01-22 Gyungmin Cho , Dohun Kim

Running scientific workflows on a supercomputer can be a daunting task for a scientific domain specialist. Workflow management solutions (WMS) are a standard method for reducing the complexity of application deployment on high performance…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-07-30 Wouter Klijn , Sandra Diaz-Pier , Abigail Morrison , Alexander Peyser

Development of machine learning (ML) workflows is a tedious process of iterative experimentation: developers repeatedly make changes to workflows until the desired accuracy is attained. We describe our vision for a "human-in-the-loop" ML…

Databases · Computer Science 2018-04-18 Doris Xin , Litian Ma , Jialin Liu , Stephen Macke , Shuchen Song , Aditya Parameswaran

The integration of Artificial Intelligence (AI) with High-Performance Computing (HPC) is transforming scientific workflows from human-directed pipelines into adaptive systems capable of autonomous decision-making. Large language models…

Computing demands for large scientific experiments, such as the CMS experiment at the CERN LHC, will increase dramatically in the next decades. To complement the future performance increases of software running on central processing units…

Instrumentation and Detectors · Physics 2024-09-09 CMS Collaboration

Scientific applications that involve simulation ensembles can be accelerated greatly by using experiment design methods to select the best simulations to perform. Methods that use machine learning (ML) to create proxy models of simulations…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-03-16 Logan Ward , Ganesh Sivaraman , J. Gregory Pauloski , Yadu Babuji , Ryan Chard , Naveen Dandu , Paul C. Redfern , Rajeev S. Assary , Kyle Chard , Larry A. Curtiss , Rajeev Thakur , Ian Foster

Quantum Computing (QC) claims to improve the efficiency of solving complex problems, compared to classical computing. When QC is integrated with Machine Learning (ML), it creates a Quantum Machine Learning (QML) system. This paper aims to…

Quantum Physics · Physics 2025-06-11 Kamila Zaman , Alberto Marchisio , Muhammad Abdullah Hanif , Muhammad Shafique

In this survey, we will explore the interaction between secure multiparty computation and the area of machine learning. Recent advances in secure multiparty computation (MPC) have significantly improved its applicability in the realm of…

Cryptography and Security · Computer Science 2025-05-22 Taobo Liao , Taoran Li , Prathamesh Nadkarni

The ubiquitous role of the cyber-infrastructures, such as the WWW, provides myriad opportunities for machine learning and its broad spectrum of application domains taking advantage of digital communication. Pattern classification and…

The amazing advances being made in the fields of machine and deep learning are a highlight of the Big Data era for both enterprise and research communities. Modern applications require resources beyond a single node's ability to provide.…

Containers offer an array of advantages that benefit research reproducibility and portability across groups and systems. As container tools mature, container security improves, and High-performance computing (HPC) and cloud system tools…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-08-24 Tiziano Müller , Nina Mujkanovic , Juan J. Durillo , Nicolay Hammer

Powerful detectors at modern experimental facilities routinely collect data at multiple GB/s. Online analysis methods are needed to enable the collection of only interesting subsets of such massive data streams, such as by explicitly…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-23 Rafael Vescovi , Ryan Chard , Nickolaus Saint , Ben Blaiszik , Jim Pruyne , Tekin Bicer , Alex Lavens , Zhengchun Liu , Michael E. Papka , Suresh Narayanan , Nicholas Schwarz , Kyle Chard , Ian Foster