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The mobility of particles in fluid membranes is a fundamental aspect of many biological processes. In a 1975 paper [1], Saffman and Delbr\"uck demonstrated how the presence of external Stokesian solvents is crucial in regularising the…

Biological Physics · Physics 2025-01-10 Marco Vona , Eric Lauga

The collective motion of membrane lipids over hundred of nanometers and nanoseconds is essential for the formation of submicron complexes of lipids and proteins in the cell membrane. These dynamics are difficult to access experimentally and…

Biological Physics · Physics 2018-08-01 Sergio Panzuela , Rafael Delgado-Buscalioni

We develop theory and computational methods to investigate particle inclusions embedded within curved lipid bilayer membranes. We consider the case of spherical lipid vesicles where inclusion particles are coupled through (i) intramembrane…

Soft Condensed Matter · Physics 2023-02-28 Jon Karl Sigurdsson , Paul J. Atzberger

Many of the cell membrane vital functions are achieved by the self-organization of the proteins and biopolymers embedded in it. The protein dynamics are in part determined by its drag. A large number of these proteins can polymerize to form…

Fluid Dynamics · Physics 2023-09-13 Wenzheng Shi , Moslem Moradi , Ehssan Nazockdast

Two-dimensional (2D) nanomaterials exhibit unique properties that are promising for diverse applications, including those relevant to concentration-gradient-driven transport of electrolyte solutions through porous membranes made from these…

Soft Condensed Matter · Physics 2025-02-21 Holly C. M. Baldock , David M. Huang

Biological swimmers frequently navigate in geometrically restricted media. We study the prescribed-stroke problem of swimmers confined to a planar viscous membrane embedded in a bulk fluid of different viscosity. In their motion,…

Soft Condensed Matter · Physics 2021-02-24 Carlos Alas , Thomas R. Powers , Tatiana Kuriabova

Recent experiments by Y. Gambin et al. [PNAS 103, 2098 (2006)] have called into question the applicability of the Saffman-Delbruck diffusivity for proteins embedded in the lipid bilayers. We present a simple argument to account for this…

Soft Condensed Matter · Physics 2009-11-13 Ali Naji , Alex J. Levine , Philip A. Pincus

This article is the second of a three-part series that derives a self-consistent theoretical framework of the electromechanics of arbitrarily curved lipid membranes. Existing continuum theories commonly treat lipid membranes as strictly…

Soft Condensed Matter · Physics 2025-02-26 Yannick A. D. Omar , Zachary G. Lipel , Kranthi K. Mandadapu

Many biological processes involve transport and organization of inclusions in thin fluid interfaces. A key aspect of these assemblies is the active dissipative stresses applied from the inclusions to the fluid interface, resulting in…

Soft Condensed Matter · Physics 2025-05-13 Arijit Mahapatra , Ronit Freeman , Ehssan Nazockdast

Gauge-theory approach to describe Dirac fermions on a disclinated flexible membrane beyond the inextensional limit is formulated. The elastic membrane is considered as an embedding of 2D surface into R^3. The disclination is incorporated…

Mesoscale and Nanoscale Physics · Physics 2015-05-19 E. A. Kochetov , V. A. Osipov , R. Pincak

In spite of many attempts to model dense granular flow, there is still no general theory capable of describing different types of flows, such as gravity-driven drainage in silos and wall-driven shear flows in Couette cells. Here, we…

Soft Condensed Matter · Physics 2009-11-11 Ken Kamrin , Chris H. Rycroft , Martin Z. Bazant

We implement a total-energy minimization scheme to allow for relaxation of atomic positions in density functional calculations for two-dimensional (2D) systems using a mixed basis set. The basis functions consist of products of 2D plane…

Materials Science · Physics 2022-03-14 Chung-Yuan Ren , Yia-Chung Chang

We construct a model to explore the hydrodynamic interactions of active inclusions in curved biological membranes. The curved membrane is modelled as a two dimensional layer of highly viscous fluid, surrounded by external solvents of…

Soft Condensed Matter · Physics 2025-06-23 Sarthak Bagaria , Rickmoy Samanta

The physics of membranes, a classic subject, acquires new momentum from two-dimensional (2D) materials multilayers. This work reports the surprising results emerged during a theoretical study of equilibrium geometry of bilayers as…

Mesoscale and Nanoscale Physics · Physics 2024-12-03 Jin Wang , Erio Tosatti

The deformation and rupture of a lipid vesicle due to the forced normal approach of an inclusion are essential for optimizing the design of magnetic giant unilamellar vesicles [magGUVs, Malik et al., Nanoscale 17, 13720 (2025)], with…

Soft Condensed Matter · Physics 2025-12-16 Yuan-Nan Young , Bryan Quaife , Herve Nganguia , On Shun Pak , Jie Feng , Howard A. Stone

The immersed boundary (IB) method has been used as a means to simulate fluid-membrane interactions in a wide variety of biological and engineering applications. Although the numerical convergence of the method has been empirically verified,…

Numerical Analysis · Mathematics 2025-10-09 Alexandre X. Milewski , Charles S. Peskin

We study the motion of a solid particle immersed in a Newtonian fluid and confined between two parallel elastic membranes possessing shear and bending rigidity. The hydrodynamic mobility depends on the frequency of the particle motion due…

Fluid Dynamics · Physics 2016-08-03 Abdallah Daddi-Moussa-Ider , Achim Guckenberger , Stephan Gekle

Making use of the system of pulling a spherical intruder in static three-dimensional granular media, we numerically study the scaling law for the drag force $F_{\rm drag}$ acting on the moving intruder under the influence of the gravity.…

Soft Condensed Matter · Physics 2020-05-13 Sonu Kumar , K. Anki Reddy , Satoshi Takada , Hisao Hayakawa

In this Letter, the 2-dimensional dense flow of polygonal particles on an incline with a flat frictional inferior boundary is analyzed by means of contact dynamics discrete element simulations, in order to develop boundary conditions for…

Soft Condensed Matter · Physics 2014-01-10 Riccardo Artoni , Andrea C. Santomaso , Massimiliano Go' , Paolo Canu

Active gel theory has recently been very successful in describing biologically active materials such as actin filaments or moving bacteria in temporally fixed and simple geometries such as cubes or spheres. Here we develop a computational…

Biological Physics · Physics 2019-07-10 Christian Bächer , Stephan Gekle
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