English
Related papers

Related papers: Deep Physiological State Space Model for Clinical …

200 papers

Longitudinal data in electronic health records (EHRs) represent an individual`s clinical history through a sequence of codified concepts, including diagnoses, procedures, medications, and laboratory tests. Generative pre-trained…

In electronic health records (EHRs), irregular time-series (ITS) occur naturally due to patient health dynamics, reflected by irregular hospital visits, diseases/conditions and the necessity to measure different vitals signs at each visit…

Machine Learning · Computer Science 2022-11-28 Vinod Kumar Chauhan , Anshul Thakur , Odhran O'Donoghue , David A. Clifton

Stochastic epidemic models which incorporate interactions between space and human mobility are a key tool to inform prioritisation of outbreak control to appropriate locations. However, methods for fitting such models to national-level…

Computational prediction of in-hospital mortality in the setting of an intensive care unit can help clinical practitioners to guide care and make early decisions for interventions. As clinical data are complex and varied in their structure…

Machine Learning · Computer Science 2020-12-29 Tingyi Wanyan , Hossein Honarvar , Ariful Azad , Ying Ding , Benjamin S. Glicksberg

Learning from longitudinal electronic health records is limited if it does not capture the temporal trajectories of the patient's state in a clinical setting. Graph models allow us to capture the hidden dependencies of the multivariate…

Machine Learning · Computer Science 2025-03-31 Munib Mesinovic , Soheila Molaei , Peter Watkinson , Tingting Zhu

State-space models (SSMs) offer a powerful framework for dynamical system analysis, wherein the temporal dynamics of the system are assumed to be captured through the evolution of the latent states, which govern the values of the…

Machine Learning · Statistics 2024-12-17 Jiahe Lin , George Michailidis

Electronic Health Records (EHRs) contain rich temporal dynamics that conventional encoding approaches fail to adequately capture. While Large Language Models (LLMs) show promise for EHR modeling, they struggle to reason about sequential…

Artificial Intelligence · Computer Science 2025-10-01 Zekai Chen , Arda Pekis , Kevin Brown

In electronic health records (EHRs), latent subgroups of patients may exhibit distinctive patterning in their longitudinal health trajectories. For such data, growth mixture models (GMMs) enable classifying patients into different latent…

Methodology · Statistics 2022-01-12 Rebecca Anthopolos , Ying Wei , Qixuan Chen

Quantification of anatomical shape changes currently relies on scalar global indexes which are largely insensitive to regional or asymmetric modifications. Accurate assessment of pathology-driven anatomical remodeling is a crucial step for…

Embeddings of medical concepts such as medication, procedure and diagnosis codes in Electronic Medical Records (EMRs) are central to healthcare analytics. Previous work on medical concept embedding takes medical concepts and EMRs as words…

Computation and Language · Computer Science 2018-06-11 Xiangrui Cai , Jinyang Gao , Kee Yuan Ngiam , Beng Chin Ooi , Ying Zhang , Xiaojie Yuan

World models offer a principled framework for simulating future states under interventions, but realizing such models in complex, high-stakes domains like medicine remains challenging. Recent large language models (LLMs) have achieved…

Artificial Intelligence · Computer Science 2026-02-04 Linjie Mu , Zhongzhen Huang , Yannian Gu , Shengqian Qin , Shaoting Zhang , Xiaofan Zhang

State-space models (SSM) with Markov switching offer a powerful framework for detecting multiple regimes in time series, analyzing mutual dependence and dynamics within regimes, and asserting transitions between regimes. These models…

Methodology · Statistics 2021-06-14 David Degras , Chee-Ming Ting , Hernando Ombao

Electronic health records (EHR) is an inherently multimodal register of the patient's health status characterized by static data and multivariate time series (MTS). While MTS are a valuable tool for clinical prediction, their fusion with…

Recent advances in deep generative models have greatly expanded the potential to create realistic synthetic health datasets. These synthetic datasets aim to preserve the characteristics, patterns, and overall scientific conclusions derived…

Machine Learning · Computer Science 2024-07-04 Jennifer A Bartell , Sander Boisen Valentin , Anders Krogh , Henning Langberg , Martin Bøgsted

Chest X-ray (CXR) is an important diagnostic tool widely used in hospitals to assess patient conditions and monitor changes over time. Recently, generative models, specifically diffusion-based models, have shown promise in generating…

Image and Video Processing · Electrical Eng. & Systems 2025-05-07 Daeun Kyung , Junu Kim , Tackeun Kim , Edward Choi

The analysis of electrophysiological data is crucial for certain surgical procedures such as deep brain stimulation, which has been adopted for the treatment of a variety of neurological disorders. During the procedure, auditory analysis of…

Machine Learning · Computer Science 2025-03-24 Thibault Martin , Paul Sauleau , Claire Haegelen , Pierre Jannin , John S. H. Baxter

Widespread adoption of electronic health records (EHRs) has fueled the development of using machine learning to build prediction models for various clinical outcomes. This process is often constrained by having a relatively small number of…

Computation and Language · Computer Science 2020-05-14 Ethan Steinberg , Ken Jung , Jason A. Fries , Conor K. Corbin , Stephen R. Pfohl , Nigam H. Shah

Increasing volume of Electronic Health Records (EHR) in recent years provides great opportunities for data scientists to collaborate on different aspects of healthcare research by applying advanced analytics to these EHR clinical data. A…

Machine Learning · Computer Science 2019-10-01 Najibesadat Sadati , Milad Zafar Nezhad , Ratna Babu Chinnam , Dongxiao Zhu

Pandemic outbreaks such as COVID-19 occur unexpectedly, and need immediate action due to their potential devastating consequences on global health. Point-of-care routine assessments such as electrocardiogram (ECG), can be used to develop…

Signal Processing · Electrical Eng. & Systems 2023-01-12 Weijie Sun , Sunil Vasu Kalmady , Nariman Sepehrvand , Luan Manh Chu , Zihan Wang , Amir Salimi , Abram Hindle , Russell Greiner , Padma Kaul

Patient representation learning refers to learning a dense mathematical representation of a patient that encodes meaningful information from Electronic Health Records (EHRs). This is generally performed using advanced deep learning methods.…

Machine Learning · Computer Science 2021-01-26 Yuqi Si , Jingcheng Du , Zhao Li , Xiaoqian Jiang , Timothy Miller , Fei Wang , W. Jim Zheng , Kirk Roberts