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Living cells move thanks to assemblies of actin filaments and myosin motors that range from very organized striated muscle tissue to disordered intracellular bundles. The mechanisms powering these disordered structures are debated, and all…

Biological Physics · Physics 2017-09-26 Martin Lenz

In these Lecture Notes we aim at clarifying how soft matter physics, and herein notably statistical mechanics and fluid mechanics, can be engaged to understand and manipulate non-equilibrium systems consisting of numerous (microscopic)…

Soft Condensed Matter · Physics 2025-05-27 Jean-François Joanny , Joseph O. Indekeu

Active solids such as cell collectives, colloidal clusters, and active metamaterials exhibit diverse collective phenomena, ranging from rigid body motion to shape-changing mechanisms. The nonlinear dynamics of such active materials remains…

Soft Condensed Matter · Physics 2024-06-21 Claudio Hernández-López , Paul Baconnier , Corentin Coulais , Olivier Dauchot , Gustavo Düring

Coupling between flows and material properties imbues rheological matter with its wide-ranging applicability, hence the excitement for harnessing the rheology of active fluids for which internal structure and continuous energy injection…

Active materials are those in which individual, uncoordinated local stresses drive the material out of equilibrium on a global scale. Examples of such assemblies can be seen across scales from schools of fish to the cellular cytoskeleton…

Soft Condensed Matter · Physics 2022-09-30 Nitin Kumar , Rui Zhang , Steven A. Redford , Juan J. de Pablo , Margaret L. Gardel

Microfluidics involves the manipulation of flows at the microscale, typically requiring external power sources to generate pressure gradients. Alternatively, harnessing flows from active fluids, which are usually chaotic, has been proposed…

The motility of a cell can be triggered or inhibited not only by an applied force but also by a mechanically neutral force couple. This type of loading, represented by an applied stress and commonly interpreted as either squeezing or…

Soft Condensed Matter · Physics 2018-01-24 Thibaut Putelat , Pierre Recho , Lev Truskinovsky

Basing our arguments on the theory of active liquid crystals, we demonstrate both analytically and numerically, that the activity can induce an effective free energy which enhances ordering in extensile systems of active rods and in…

Soft Condensed Matter · Physics 2015-10-27 Sumesh P. Thampi , Amin Doostmohammadi , Ramin Golestanian , Julia M. Yeomans

Pattern formation and the mechanics of a mixture of actin filaments and myosin motors that is confined by a rigid membrane is investigated. By using a coarse-grained molecular dynamics model, we demonstrate that the competition between the…

Soft Condensed Matter · Physics 2023-04-12 Mitsusuke Tarama , Tatsuo Shibata

The emergence of long-range spatiotemporal order from intrinsic chaos is a central challenge in far-from-equilibrium physics. In active fluids, such as cytoskeletal networks driving cellular motion, self-generated flows typically produce…

Cytoskeletal networks, which are essentially motor-filament assemblies, play a major role in many developmental processes involving structural remodeling and shape changes. These are achieved by nonequilibrium self-organization processes…

Soft Condensed Matter · Physics 2014-12-22 Shenshen Wang , Peter G. Wolynes

Achieving control and tunability of lyotropic materials has been a long-standing goal of liquid crystal research. Here we show that the elasticity of a liquid crystal system consisting of a dense suspension of semiflexible biopolymers can…

Soft Condensed Matter · Physics 2018-01-12 Rui Zhang , Nitin Kumar , Jennifer Ross , Margaret L. Gardel , Juan J. de Pablo

In this work we present the first systematic framework to sculpt active nematics systems, using optimal control theory and a hydrodynamic model of active nematics. We demonstrate the use of two different control fields, (1) applied…

Soft Condensed Matter · Physics 2020-10-28 Michael M. Norton , Piyush Grover , Michael F. Hagan , Seth Fraden

Active systems, from bacterial suspensions to cellular monolayers, are continuously driven out of equilibrium by local injection of energy from their constituent elements and exhibit turbulent-like and chaotic patterns. Here we demonstrate…

Soft Condensed Matter · Physics 2016-02-04 Amin Doostmohammadi , Michael F. Adamer , Sumesh P. Thampi , Julia M. Yeomans

A paradigm for internally driven matter is the active nematic liquid crystal, whereby the equations of a conventional nematic are supplemented by a minimal active stress that violates time reversal symmetry. In practice, active fluids may…

Soft Condensed Matter · Physics 2015-12-15 E. J. Hemingway , A. Maitra , S. Banerjee , M. C. Marchetti , S. Ramaswamy , S. M. Fielding , M. E. Cates

We study the dynamics of a tunable 2D active nematic liquid crystal composed of microtubules and kinesin motors confined to an oil-water interface. Kinesin motors continuously inject mechanical energy into the system through ATP hydrolysis,…

Soft Condensed Matter · Physics 2019-09-10 Linnea M Lemma , Stephen J Decamp , Zhihong You , Luca Giomi , Zvonimir Dogic

Active colloids and liquid crystals are capable of locally converting the macroscopically-supplied energy into directional motion and promise a host of new applications, ranging from drug delivery to cargo transport at the mesoscale. Here…

Internally generated active stresses drive soft materials into architectures inaccessible to thermal self-assembly. We use a microtubule-based active fluid to assemble and irreversibly restructure actin-fascin networks. Subsequently, we…

Soft Condensed Matter · Physics 2026-05-13 Kyu Hwan Choi , Sattvic Ray , Reef Sweeney , Zvonimir Dogic , Sho C. Takatori

Active fluids generate spontaneous, often chaotic mesoscale flows. Harnessing these flows to drive embedded soft materials into structures with controlled length scales and lifetimes is a key challenge at the interface between the fields of…

Soft Condensed Matter · Physics 2025-02-19 Layne B. Frechette , Aparna Baskaran , Michael F. Hagan

Materials of which the optical response is determined by their structure are of much interest both for their fundamental properties and applications. Examples range from simple gratings to photonic crystals. Obtaining control over the…