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We propose a set of kernel-based tools to evaluate the designs and tune the hyperparameters of conditional sequence models, with a focus on problems in computational biology. The backbone of our tools is a new measure of discrepancy between…

Machine Learning · Statistics 2025-10-20 Pierre Glaser , Steffanie Paul , Alissa M. Hummer , Charlotte M. Deane , Debora S. Marks , Alan N. Amin

This paper addresses the covariate shift problem in the context of nonparametric regression within reproducing kernel Hilbert spaces (RKHSs). Covariate shift arises in supervised learning when the input distributions of the training and…

Machine Learning · Statistics 2025-05-21 Andrea Della Vecchia , Arnaud Mavakala Watusadisi , Ernesto De Vito , Lorenzo Rosasco

Reproducing kernel Hilbert spaces (RKHSs) play an important role in many statistics and machine learning applications ranging from support vector machines to Gaussian processes and kernel embeddings of distributions. Operators acting on…

Functional Analysis · Mathematics 2021-04-06 Mattes Mollenhauer , Ingmar Schuster , Stefan Klus , Christof Schütte

Matrix approximations are a key element in large-scale algebraic machine learning approaches. The recently proposed method MEKA (Si et al., 2014) effectively employs two common assumptions in Hilbert spaces: the low-rank property of an…

Machine Learning · Computer Science 2022-01-21 Simon Heilig , Maximilian Münch , Frank-Michael Schleif

We consider the problem of conditional independence (CI) testing and adopt a kernel-based approach. Kernel-based CI tests embed variables in reproducing kernel Hilbert spaces, regress their embeddings on the conditioning variables, and test…

Machine Learning · Statistics 2026-04-07 Luca Bergen , Dino Sejdinovic , Vanessa Didelez

Multivariate probit models (MPM) have the appealing feature of capturing some of the dependence structure between the components of multidimensional binary responses. The key for the dependence modelling is the covariance matrix of an…

Methodology · Statistics 2013-11-15 Giusi Moffa , Jack Kuipers

Estimation of the mean vector and covariance matrix is of central importance in the analysis of multivariate data. In the framework of generalized linear models, usually the variances are certain functions of the means with the normal…

Methodology · Statistics 2023-01-25 Anupam Kundu , Mohsen Pourahmadi

We provide a theoretical foundation for non-parametric estimation of functions of random variables using kernel mean embeddings. We show that for any continuous function $f$, consistent estimators of the mean embedding of a random variable…

Machine Learning · Statistics 2018-06-04 Carl-Johann Simon-Gabriel , Adam Ścibior , Ilya Tolstikhin , Bernhard Schölkopf

Gaussian mixture models (GMMs) are ubiquitous in statistical learning, particularly for unsupervised problems. While full GMMs suffer from the overparameterization of their covariance matrices in high-dimensional spaces, spherical GMMs…

Machine Learning · Statistics 2025-11-10 Tom Szwagier , Pierre-Alexandre Mattei , Charles Bouveyron , Xavier Pennec

Motivated by applications to the study of stochastic processes, we introduce a new analysis of positive definite kernels $K$, their reproducing kernel Hilbert spaces (RKHS), and an associated family of feature spaces that may be chosen in…

Functional Analysis · Mathematics 2017-07-27 Palle Jorgensen , Feng Tian

This monograph develops a unified, application-driven framework for kernel methods grounded in reproducing kernel Hilbert spaces (RKHS) and optimal transport (OT). Part I lays the theoretical and numerical foundations on positive-definite…

Numerical Analysis · Mathematics 2025-10-07 Philippe G. LeFloch , Jean-Marc Mercier , Shohruh Miryusupov

We study empirical Bayes (EB) predictive density estimation in linear mixed models (LMMs) with large number of units, which induce a high dimensional random effects space. Focusing on Kullback Leibler (KL) risk minimization, we develop a…

Methodology · Statistics 2026-03-31 Abir Sarkar , Gourab Mukherjee , Keisuke Yano

This paper proposes a Conditional Method Confidence Set (CMCS) which allows to select the best subset of forecasting methods with equal predictive ability conditional on a specific economic regime. The test resembles the Model Confidence…

Econometrics · Economics 2025-05-28 Lukas Bauer , Ekaterina Kazak

Reproducing kernel Hilbert spaces (RKHSs) are special Hilbert spaces where all the evaluation functionals are linear and bounded. They are in one-to-one correspondence with positive definite maps called kernels. Stable RKHSs enjoy the…

Systems and Control · Electrical Eng. & Systems 2023-05-04 Mauro Bisiacco , Gianluigi Pillonetto

Probabilistic predictions are probability distributions over the set of possible outcomes. Such predictions quantify the uncertainty in the outcome, making them essential for effective decision making. By combining multiple predictions, the…

Machine Learning · Statistics 2024-11-26 Sam Allen , David Ginsbourger , Johanna Ziegel

In this paper, an adaptive non-parametric method is proposed to estimate the scalar-valued nonlinear function that appears in uncertain systems governed by ordinary differential equations (ODEs). By employing an infinite-dimensional…

Optimization and Control · Mathematics 2021-03-15 Jia Guo , Sai Tej Paruchuri , Andrew J. Kurdila

Bayesian calibration of black-box computer models offers an established framework to obtain a posterior distribution over model parameters. Traditional Bayesian calibration involves the emulation of the computer model and an additive model…

Machine Learning · Statistics 2018-10-30 Sébastien Marmin , Maurizio Filippone

In modern data analysis, nonparametric measures of discrepancies between random variables are particularly important. The subject is well-studied in the frequentist literature, while the development in the Bayesian setting is limited where…

Methodology · Statistics 2022-01-25 Qinyi Zhang , Veit Wild , Sarah Filippi , Seth Flaxman , Dino Sejdinovic

Conditional distributions, as defined by the Markov category framework, are studied in the setting of matrix algebras (quantum systems). Their construction as linear unital maps are obtained via a categorical Bayesian inversion procedure.…

Quantum Physics · Physics 2021-09-14 Arthur J. Parzygnat

We present a novel kernel-based machine learning algorithm for identifying the low-dimensional geometry of the effective dynamics of high-dimensional multiscale stochastic systems. Recently, the authors developed a mathematical framework…

Dynamical Systems · Mathematics 2020-02-04 Andreas Bittracher , Stefan Klus , Boumediene Hamzi , Péter Koltai , Christof Schütte