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Semantic image segmentation is one of the most important tasks in medical image analysis. Most state-of-the-art deep learning methods require a large number of accurately annotated examples for model training. However, accurate annotation…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Ning Zhang , Susan Francis , Rayaz Malik , Xin Chen

Understanding the uncertainty inherent in deep learning-based image registration models has been an ongoing area of research. Existing methods have been developed to quantify both transformation and appearance uncertainties related to the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-11 Junyu Chen , Yihao Liu , Shuwen Wei , Zhangxing Bian , Aaron Carass , Yong Du

Deep neural networks for medical image segmentation often produce overconfident results misaligned with empirical observations. Such miscalibration, challenges their clinical translation. We propose to use marginal L1 average calibration…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Theodore Barfoot , Luis Garcia-Peraza-Herrera , Ben Glocker , Tom Vercauteren

PURPOSE: To apply deep CNN to the segmentation task in myocardial arterial spin labeled (ASL) perfusion imaging and to develop methods that measure uncertainty and that adapt the CNN model to a specific false positive vs. false negative…

Computer Vision and Pattern Recognition · Computer Science 2019-11-06 Hung P. Do , Yi Guo , Andrew J. Yoon , Krishna S. Nayak

The investigation of uncertainty is of major importance in risk-critical applications, such as medical image segmentation. Belief function theory, a formal framework for uncertainty analysis and multiple evidence fusion, has made…

Computer Vision and Pattern Recognition · Computer Science 2022-12-07 Ling Huang , Su Ruan , Thierry Denoeux

Model calibration measures the agreement between the predicted probability estimates and the true correctness likelihood. Proper model calibration is vital for high-risk applications. Unfortunately, modern deep neural networks are poorly…

Image and Video Processing · Electrical Eng. & Systems 2022-09-14 Skylar E. Stolte , Kyle Volle , Aprinda Indahlastari , Alejandro Albizu , Adam J. Woods , Kevin Brink , Matthew Hale , Ruogu Fang

Deep neural networks (DNNs) achieve promising performance in visual recognition under the independent and identically distributed (IID) hypothesis. In contrast, the IID hypothesis is not universally guaranteed in numerous real-world…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Shuai Wang , Zipei Yan , Daoan Zhang , Zhongsen Li , Sirui Wu , Wenxuan Chen , Rui Li

Automatic medical image segmentation, an essential component of medical image analysis, plays an importantrole in computer-aided diagnosis. For example, locating and segmenting the liver can be very helpful in livercancer diagnosis and…

Image and Video Processing · Electrical Eng. & Systems 2019-10-28 Xi Fang , Bo Du , Sheng Xu , Bradford J. Wood , Pingkun Yan

Automated medical image segmentation, specifically using deep learning, has shown outstanding performance in semantic segmentation tasks. However, these methods rarely quantify their uncertainty, which may lead to errors in downstream…

Computer Vision and Pattern Recognition · Computer Science 2018-06-25 Zach Eaton-Rosen , Felix Bragman , Sotirios Bisdas , Sebastien Ourselin , M. Jorge Cardoso

Discriminative convolutional neural networks (CNNs), for which a voxel-wise conditional Multinoulli distribution is assumed, have performed well in many brain lesion segmentation tasks. For a trained discriminative CNN to be used in…

Image and Video Processing · Electrical Eng. & Systems 2021-02-22 Kevin Raina

Convolutional neural networks (CNN) have had unprecedented success in medical imaging and, in particular, in medical image segmentation. However, despite the fact that segmentation results are closer than ever to the inter-expert…

Computer Vision and Pattern Recognition · Computer Science 2020-06-17 Nathan Painchaud , Youssef Skandarani , Thierry Judge , Olivier Bernard , Alain Lalande , Pierre-Marc Jodoin

The performance of deep learning (DL) methods for the analysis of cine cardiovascular magnetic resonance (CMR) is typically assessed in terms of accuracy, overlooking precision. In this work, uncertainty estimation techniques, namely deep…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Dewmini Hasara Wickremasinghe , Michelle Gibogwe , Andrew Bell , Esther Puyol-Antón , Muhummad Sohaib Nazir , Reza Razavi , Bruno Paun , Paul Aljabar , Andrew P. King

Medical image segmentation serves as a critical component of precision medicine, enabling accurate localization and delineation of pathological regions, such as lesions. However, existing models empirically apply fixed thresholds (e.g.,…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Binyu Tan , Zhiyuan Wang , Jinhao Duan , Kaidi Xu , Heng Tao Shen , Xiaoshuang Shi , Fumin Shen

Quality control (QC) of MR images is essential to ensure that downstream analyses such as segmentation can be performed successfully. Currently, QC is predominantly performed visually and subjectively, at significant time and operator cost.…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Richard Shaw , Carole H. Sudre , Sebastien Ourselin , M. Jorge Cardoso , Hugh G. Pemberton

X-Ray image enhancement, along with many other medical image processing applications, requires the segmentation of images into bone, soft tissue, and open beam regions. We apply a machine learning approach to this problem, presenting an…

Computer Vision and Pattern Recognition · Computer Science 2019-04-23 Joseph Bullock , Carolina Cuesta-Lazaro , Arnau Quera-Bofarull

Fully convolutional deep neural networks have been asserted to be fast and precise frameworks with great potential in image segmentation. One of the major challenges in training such networks raises when data is unbalanced, which is common…

Computer Vision and Pattern Recognition · Computer Science 2018-12-17 Seyed Raein Hashemi , Seyed Sadegh Mohseni Salehi , Deniz Erdogmus , Sanjay P. Prabhu , Simon K. Warfield , Ali Gholipour

Medical image segmentation modeling is a high-stakes task where understanding of uncertainty is crucial for addressing visual ambiguity. Prior work has developed segmentation models utilizing probabilistic or generative mechanisms to infer…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Andre Ye , Quan Ze Chen , Amy Zhang

In recent years, Deep Learning (DL) has shown promising results in conducting AI tasks such as computer vision and image segmentation. Specifically, Convolutional Neural Network (CNN) models in DL have been applied to prevention,detection,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Ahmed Awad Albishri , Syed Jawad Hussain Shah , Anthony Schmiedler , Seung Suk Kang , Yugyung Lee

Although deep learning prediction models have been successful in the discrimination of different classes, they can often suffer from poor calibration across challenging domains including healthcare. Moreover, the long-tail distribution…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Riqiang Gao , Thomas Li , Yucheng Tang , Zhoubing Xu , Michael Kammer , Sanja L. Antic , Kim Sandler , Fabien Moldonado , Thomas A. Lasko , Bennett Landman

Uncertainty estimation has been widely studied in medical image segmentation as a tool to provide reliability, particularly in deep learning approaches. However, previous methods generally lack effective supervision in uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Yuzhu Li , An Sui , Fuping Wu , Xiahai Zhuang