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Volumetric cell segmentation in fluorescence microscopy images is important to study a wide variety of cellular processes. Applications range from the analysis of cancer cells to behavioral studies of cells in the embryonic stage. Like in…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Royden Wagner , Karl Rohr

Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

Deep learning provides us with powerful methods to perform nucleus or cell segmentation with unprecedented quality. However, these methods usually require large training sets of manually annotated images, which are tedious and expensive to…

Image and Video Processing · Electrical Eng. & Systems 2023-01-11 Thomas Bonte , Maxence Philbert , Emeline Coleno , Edouard Bertrand , Arthur Imbert , Thomas Walter

Cell detection is an essential task in cell image analysis. Recent deep learning-based detection methods have achieved very promising results. In general, these methods require exhaustively annotating the cells in an entire image. If some…

Computer Vision and Pattern Recognition · Computer Science 2021-07-22 Kazuma Fujii , Daiki Suehiro , Kazuya Nishimura , Ryoma Bise

Precise identification of multiple cell classes in high-resolution Giga-pixel whole slide imaging (WSI) is critical for various clinical scenarios. Building an AI model for this purpose typically requires pixel-level annotations, which are…

Image and Video Processing · Electrical Eng. & Systems 2023-08-14 Xueyuan Li , Ruining Deng , Yucheng Tang , Shunxing Bao , Haichun Yang , Yuankai Huo

We tackle biomedical image segmentation in the scenario of only a few labeled brain MR images. This is an important and challenging task in medical applications, where manual annotations are time-consuming. Current multi-atlas based…

Computer Vision and Pattern Recognition · Computer Science 2020-01-14 Hyeon Woo Lee , Mert R. Sabuncu , Adrian V. Dalca

We present an unsupervised deep learning method for text line segmentation that is inspired by the relative variance between text lines and spaces among text lines. Handwritten text line segmentation is important for the efficiency of…

Computer Vision and Pattern Recognition · Computer Science 2020-10-27 Berat Kurar Barakat , Ahmad Droby , Rym Alasam , Boraq Madi , Irina Rabaev , Raed Shammes , Jihad El-Sana

3D semantic scene understanding tasks have achieved great success with the emergence of deep learning, but often require a huge amount of manually annotated training data. To alleviate the annotation cost, we propose the first…

Computer Vision and Pattern Recognition · Computer Science 2023-08-04 Shichao Dong , Guosheng Lin

Instance segmentation in 3D images is a fundamental task in biomedical image analysis. While deep learning models often work well for 2D instance segmentation, 3D instance segmentation still faces critical challenges, such as insufficient…

Computer Vision and Pattern Recognition · Computer Science 2018-07-02 Zhuo Zhao , Lin Yang , Hao Zheng , Ian H. Guldner , Siyuan Zhang , Danny Z. Chen

Instance segmentation enables the analysis of spatial and temporal properties of cells in microscopy images by identifying the pixels belonging to each cell. However, progress is constrained by the scarcity of high-quality labeled…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Kaden Stillwagon , Alexandra Dunnum VandeLoo , Benjamin Magondu , Craig R. Forest

Annotation of medical images has been a major bottleneck for the development of accurate and robust machine learning models. Annotation is costly and time-consuming and typically requires expert knowledge, especially in the medical domain.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-08 Holger Roth , Ling Zhang , Dong Yang , Fausto Milletari , Ziyue Xu , Xiaosong Wang , Daguang Xu

This paper presents a novel approach for learning instance segmentation with image-level class labels as supervision. Our approach generates pseudo instance segmentation labels of training images, which are used to train a fully supervised…

Computer Vision and Pattern Recognition · Computer Science 2019-05-13 Jiwoon Ahn , Sunghyun Cho , Suha Kwak

In the effort to aid cytologic diagnostics by establishing automatic single cell screening using high throughput digital holographic microscopy for clinical studies thousands of images and millions of cells are captured. The bottleneck lies…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Julia Sistermanns , Ellen Emken , Gregor Weirich , Oliver Hayden , Wolfgang Utschick

As a computer vision task, automatic object segmentation remains challenging in specialized image domains without massive labeled data, such as synthetic aperture sonar images, remote sensing, biomedical imaging, etc. In any domain,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-05 Hassan Baker , Matthew S. Emigh , Austin J. Brockmeier

Despite their superior performance, deep-learning methods often suffer from the disadvantage of needing large-scale well-annotated training data. In response, recent literature has seen a proliferation of efforts aimed at reducing the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Ji Yu

Accurate identification of breast masses is crucial in diagnosing breast cancer; however, it can be challenging due to their small size and being camouflaged in surrounding normal glands. Worse still, it is also expensive in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Xinyu Xiong , Churan Wang , Wenxue Li , Guanbin Li

Segmenting histology images into diagnostically relevant regions is imperative to support timely and reliable decisions by pathologists. To this end, computer-aided techniques have been proposed to delineate relevant regions in scanned…

Weakly Supervised Semantic Segmentation (WSSS) is a challenging task aiming to learn the segmentation labels from class-level labels. In the literature, exploiting the information obtained from Class Activation Maps (CAMs) is widely used…

Computer Vision and Pattern Recognition · Computer Science 2022-11-24 Cenk Bircanoglu , Nafiz Arica

Recently proposed methods for weakly-supervised semantic segmentation have achieved impressive performance in predicting pixel classes despite being trained with only image labels which lack positional information. Because image annotations…

Computer Vision and Pattern Recognition · Computer Science 2020-10-20 Lyndon Chan , Mahdi S. Hosseini , Konstantinos N. Plataniotis

We introduce CellSegmenter, a structured deep generative model and an amortized inference framework for unsupervised representation learning and instance segmentation tasks. The proposed inference algorithm is convolutional and…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Luca D'Alessio , Mehrtash Babadi