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The increasing availability of unstructured clinical narratives in electronic health records (EHRs) has created new opportunities for automated disease characterization, cohort identification, and clinical decision support. However,…

Computation and Language · Computer Science 2026-03-03 Fariba Afrin Irany , Sampson Akwafuo

While the ICD code assignment problem has been widely studied, most works have focused on post-discharge document classification. Models for early forecasting of this information could be used for identifying health risks, suggesting…

Machine Learning · Computer Science 2025-08-18 Cindy Shih-Ting Huang , Clarence Boon Liang Ng , Marek Rei

Electronic health records (EHR) offer unprecedented opportunities for in-depth clinical phenotyping and prediction of clinical outcomes. Combining multiple data sources is crucial to generate a complete picture of disease prevalence,…

Computation and Language · Computer Science 2022-12-01 Anna Munoz-Farre , Harry Rose , Sera Aylin Cakiroglu

Clinical information extraction, which involves structuring clinical concepts from unstructured medical text, remains a challenging problem that could benefit from the inclusion of tabular background information available in electronic…

Artificial Intelligence · Computer Science 2025-12-10 Paloma Rabaey , Stefan Heytens , Thomas Demeester

Clinical notes contain a large amount of clinically valuable information that is ignored in many clinical decision support systems due to the difficulty that comes with mining that information. Recent work has found success leveraging deep…

Machine Learning · Computer Science 2019-11-13 Justin R. Lovelace , Nathan C. Hurley , Adrian D. Haimovich , Bobak J. Mortazavi

The large amount of time clinicians spend sifting through patient notes and documenting in electronic health records (EHRs) is a leading cause of clinician burnout. By proactively and dynamically retrieving relevant notes during the…

Information Retrieval · Computer Science 2023-08-17 Sharon Jiang , Shannon Shen , Monica Agrawal , Barbara Lam , Nicholas Kurtzman , Steven Horng , David Karger , David Sontag

Electronic health records (EHR) is an inherently multimodal register of the patient's health status characterized by static data and multivariate time series (MTS). While MTS are a valuable tool for clinical prediction, their fusion with…

As two important textual modalities in electronic health records (EHR), both structured data (clinical codes) and unstructured data (clinical narratives) have recently been increasingly applied to the healthcare domain. Most existing…

Computation and Language · Computer Science 2022-11-01 Sicen Liu , Xiaolong Wang , Yongshuai Hou , Ge Li , Hui Wang , Hui Xu , Yang Xiang , Buzhou Tang

Electronic Health Records (EHRs) offer considerable potential for clinical prediction, but their complexity and heterogeneity challenge traditional machine learning. Domain-specific EHR foundation models trained on unlabeled EHR data have…

In this work we addressed the problem of capturing sequential information contained in longitudinal electronic health records (EHRs). Clinical notes, which is a particular type of EHR data, are a rich source of information and practitioners…

Computation and Language · Computer Science 2020-10-27 Andrey Kormilitzin , Nemanja Vaci , Qiang Liu , Hao Ni , Goran Nenadic , Alejo Nevado-Holgado

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

Rare diseases pose significant challenges in diagnosis and treatment due to their low prevalence and heterogeneous clinical presentations. Unstructured clinical notes contain valuable information for identifying rare diseases, but manual…

Computation and Language · Computer Science 2024-11-12 Jinge Wu , Hang Dong , Zexi Li , Haowei Wang , Runci Li , Arijit Patra , Chengliang Dai , Waqar Ali , Phil Scordis , Honghan Wu

Accurate classification of clinical text often requires fine-tuning pre-trained language models, a process that is costly and time-consuming due to the need for high-quality data and expert annotators. Synthetic data generation offers an…

Computation and Language · Computer Science 2025-01-28 Ivan Lopez , Fateme Nateghi Haredasht , Kaitlin Caoili , Jonathan H Chen , Akshay Chaudhari

Disease risk prediction has attracted increasing attention in the field of modern healthcare, especially with the latest advances in artificial intelligence (AI). Electronic health records (EHRs), which contain heterogeneous patient…

Artificial Intelligence · Computer Science 2022-01-19 Shuai Niu , Qing Yin , Yunya Song , Yike Guo , Xian Yang

Electronic Healthcare Records contain large volumes of unstructured data, including extensive free text. Yet this source of detailed information often remains under-used because of a lack of methodologies to extract interpretable content in…

Computation and Language · Computer Science 2018-07-10 M. Tarik Altuncu , Erik Mayer , Sophia N. Yaliraki , Mauricio Barahona

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

Machine Learning · Computer Science 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

Clinical notes are often stored in unstructured or semi-structured formats after extraction from electronic medical record (EMR) systems, which complicates their use for secondary analysis and downstream clinical applications. Reliable…

Computation and Language · Computer Science 2025-12-30 Risha Surana , Adrian Law , Sunwoo Kim , Rishab Sridhar , Angxiao Han , Peiyu Hong

Electronic Health Records (EHRs) exhibit a high amount of missing data due to variations of patient conditions and treatment needs. Imputation of missing values has been considered an effective approach to deal with this challenge. Existing…

Machine Learning · Computer Science 2022-10-25 Yuxi Liu , Shaowen Qin , Zhenhao Zhang , Wei Shao

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

Machine Learning · Computer Science 2025-11-07 Anzhuo Xie , Wei-Chen Chang

We present a system that uses a learned autocompletion mechanism to facilitate rapid creation of semi-structured clinical documentation. We dynamically suggest relevant clinical concepts as a doctor drafts a note by leveraging features from…

Machine Learning · Computer Science 2020-07-31 Divya Gopinath , Monica Agrawal , Luke Murray , Steven Horng , David Karger , David Sontag
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