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Complex networks encountered in biology are often characterized by significant structural diversity. Whether it be differences in the three-dimensional structure of allosteric proteins, or the variation among the micro-scale structures of…

Physics and Society · Physics 2020-08-19 Jason W. Rocks , Andrea J. Liu , Eleni Katifori

Nature is rife with networks that are functionally optimized to propagate inputs in order to perform specific tasks. Whether via genetic evolution or dynamic adaptation, many networks create functionality by locally tuning interactions…

Soft Condensed Matter · Physics 2019-02-14 Jason W. Rocks , Henrik Ronellenfitsch , Andrea J. Liu , Sidney R. Nagel , Eleni Katifori

This Letter presents a unified approach for the fundamental relationship between structure and function in flow networks by solving analytically the voltages in a resistor network, transforming the network structure to an effective…

Physics and Society · Physics 2015-06-12 Nicolás Rubido , Celso Grebogi , Murilo S. Baptista

A common feature of biological networks is the geometric property of self-similarity. Molecular regulatory networks through to circulatory systems, nervous systems, social systems and ecological trophic networks, show self-similar…

Molecular Networks · Quantitative Biology 2012-03-09 Simon DeDeo , David C. Krakauer

The human organism is an integrated network where complex physiologic systems, each with its own regulatory mechanisms, continuously interact, and where failure of one system can trigger a breakdown of the entire network. Identifying and…

Data Analysis, Statistics and Probability · Physics 2012-03-02 Amir Bashan , Ronny P. Bartsch , Jan W. Kantelhardt , Shlomo Havlin , Plamen Ch. Ivanov

Flow networks are essential for both living organisms and enginneered systems. These networks often present complex dynamics controlled, at least in part, by their topology. Previous works have shown that topologically complex networks…

Soft Condensed Matter · Physics 2020-03-24 Miguel Ruiz-Garcia , Eleni Katifori

The topology of many real complex networks has been conjectured to be embedded in hidden metric spaces, where distances between nodes encode their likelihood of being connected. Besides of providing a natural geometrical interpretation of…

Physics and Society · Physics 2017-01-23 Antoine Allard , M. Ángeles Serrano , Guillermo García-Pérez , Marián Boguñá

The structure of flow networks determines their function under normal conditions as well as their response to perturbative damage. Brain vasculature often experiences transient or permanent occlusions in the finest vessels, but it is not…

Disordered Systems and Neural Networks · Physics 2019-02-06 Tatyana Gavrilchenko , Eleni Katifori

Recent evidence indicates that the abundance of recurring elementary interaction patterns in complex networks, often called subgraphs or motifs, carry significant information about their function and overall organization. Yet, the…

Disordered Systems and Neural Networks · Physics 2009-11-10 A. Vazquez , R. Dobrin , D. Sergi , J. -P. Eckmann , Z. N. Oltvai , A. -L. Barabasi

Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the underlying anatomical or structural network of synaptic connections. This latter is well…

Disordered Systems and Neural Networks · Physics 2021-02-11 Ali Safari , Paolo Moretti , Ibai Diez , Jesus M. Cortes , Miguel Ángel Muñoz

The statistical mechanical approach to complex networks is the dominant paradigm in describing natural and societal complex systems. The study of network properties, and their implications on dynamical processes, mostly focus on locally…

Statistical Mechanics · Physics 2013-06-27 Giovanni Petri , Martina Scolamiero , Irene Donato , Francesco Vaccarino

Complex distribution networks are pervasive in biology. Examples include nutrient transport in the slime mold \emph{Physarum polycephalum} as well as mammalian and plant venation. Adaptive rules are believed to guide development of these…

Adaptation and Self-Organizing Systems · Physics 2019-12-16 Henrik Ronellenfitsch , Eleni Katifori

The relationship between the regulatory design and the functionality of molecular networks is a key issue in biology. Modules and motifs have been associated to various cellular processes, thereby providing anecdotal evidence for…

Molecular Networks · Quantitative Biology 2008-03-04 Jacob Bock Axelsen , Sebastian Bernhardsson , Kim Sneppen

We consider the dynamics of a reaction-diffusion system on a multigraph. The species share the same set of nodes but can access different links to explore the embedding spatial support. By acting on the topology of the networks we can…

Statistical Mechanics · Physics 2016-12-21 Malbor Asllani , Timoteo Carletti , Duccio Fanelli

The behavior of complex systems is determined not only by the topological organization of their interconnections but also by the dynamical processes taking place among their constituents. A faithful modeling of the dynamics is essential…

Physics and Society · Physics 2015-05-20 R. Lambiotte , R. Sinatra , J. -C. Delvenne , T. S. Evans , M. Barahona , V. Latora

One major open problem in network coding is to characterize the capacity region of a general multi-source multi-demand network. There are some existing computational tools for bounding the capacity of general networks, but their…

Information Theory · Computer Science 2015-03-17 Michelle Effros , Tracey Ho , Shirin Jalali

Networked structure emerged from a wide range of fields such as biological systems, World Wide Web and technological infrastructure. A deeply insight into the topological complexity of these networks has been gained. Some works start to pay…

Physics and Society · Physics 2012-02-03 Jiang Xiongfei

Over the past decade, a number of researchers in systems biology have sought to relate the function of biological systems to their network-level descriptions -- lists of the most important players and the pairwise interactions between them.…

Molecular Networks · Quantitative Biology 2012-03-14 Andrew Mugler , Boris Grinshpun , Riley Franks , Chris H. Wiggins

Functional networks of complex systems are obtained from the analysis of the temporal activity of their components, and are often used to infer their unknown underlying connectivity. We obtain the equations relating topology and function in…

Disordered Systems and Neural Networks · Physics 2015-03-18 Víctor M. Eguíluz , Toni Pérez , Javier Borge-Holtoefer , Alex Arenas

Transport networks are crucial to the functioning of natural and technological systems. Nature features transport networks that are adaptive over a vast range of parameters, thus providing an impressive level of robustness in supply.…

Adaptation and Self-Organizing Systems · Physics 2017-11-28 Erik Andreas Martens , Konstantin Klemm
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