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In this work, we present a new approach for constructing models for correlation matrices with a user-defined graphical structure. The graphical structure makes correlation matrices interpretable and avoids the quadratic increase of…

Modern biomedical datasets are increasingly high dimensional and exhibit complex correlation structures. Generalized Linear Mixed Models (GLMMs) have long been employed to account for such dependencies. However, proper specification of the…

In this paper, we introduce a novel high-dimensional Factor-Adjusted sparse Partially Linear regression Model (FAPLM), to integrate the linear effects of high-dimensional latent factors with the nonparametric effects of low-dimensional…

Methodology · Statistics 2025-01-14 Yanmei Shi , Meiling Hao , Yanlin Tang , Xu Guo

Two popular approaches for relating correlated measurements of a non-Gaussian response variable to a set of predictors are to fit a marginal model using generalized estimating equations and to fit a generalized linear mixed model by…

Methodology · Statistics 2017-02-23 Jeffrey J. Gory , Peter F. Craigmile , Steven N. MacEachern

A linear multi-factor model is one of the most important tools in equity portfolio management. The linear multi-factor models are widely used because they can be easily interpreted. However, financial markets are not linear and their…

Machine Learning · Computer Science 2019-02-01 Kei Nakagawa , Tomoki Ito , Masaya Abe , Kiyoshi Izumi

Tissue growth underpins a wide array of biological and developmental processes, and numerical modeling of growing systems has been shown to be a useful tool for understanding these processes. However, the phenomena that can be captured are…

Soft Condensed Matter · Physics 2023-11-08 Andrew Killeen , Benjamin Partridge , Thibault Bertrand , Chiu Fan Lee

Growth charts are often more informative when they are customized per subject, taking into account prior measurements and possibly other covariates of the subject. We study a global semiparametric quantile regression model that has the…

Statistics Theory · Mathematics 2007-06-13 Ying Wei , Xuming He

Using Non-negative Matrix Factorization (NMF), the observed matrix can be approximated by the product of the basis and coefficient matrices. Moreover, if the coefficient vectors are explained by the covariates for each individual, the…

Methodology · Statistics 2025-01-30 Kenichi Satoh

Researchers are often interested in examining between-individual differences in within-individual processes. If the process under investigation is tracked for a long time, its trajectory may show a certain degree of nonlinearity, so that…

Methodology · Statistics 2025-12-02 Jin Liu , Robert A. Perera

Inspired by the complexity of certain real-world datasets, this article introduces a novel flexible linear spline index regression model. The model posits piecewise linear effects of an index on the response, with continuous changes…

Methodology · Statistics 2024-09-04 Lianqiang Qu , Long Lv , Meiling Hao , Liuquan Sun

Longitudinal study designs are indispensable for studying disease progression. Inferring covariate effects from longitudinal data, however, requires interpretable methods that can model complicated covariance structures and detect nonlinear…

Machine Learning · Statistics 2022-10-27 Juho Timonen , Henrik Mannerström , Aki Vehtari , Harri Lähdesmäki

The problem of detecting change points in the parameters of a linear regression model with errors and covariates exhibiting heteroscedasticity is considered. Asymptotic results for weighted functionals of the cumulative sum (CUSUM)…

Econometrics · Economics 2025-10-28 Lajos Horvath , Gregory Rice , Yuqian Zhao

Linear mixed models (LMMs) are a powerful and established tool for studying genotype-phenotype relationships. A limiting assumption of LMMs is that the residuals are Gaussian distributed, a requirement that rarely holds in practice.…

Genomics · Quantitative Biology 2014-08-10 Nicolo Fusi , Christoph Lippert , Neil D. Lawrence , Oliver Stegle

Spatial econometric research typically relies on the assumption that the spatial dependence structure is known in advance and is represented by a deterministic spatial weights matrix. Contrary to classical approaches, we investigate the…

Computation · Statistics 2023-10-24 Miryam S. Merk , Philipp Otto

Statistical evaluation aims to estimate the generalization performance of a model using held-out i.i.d.\ test data sampled from the ground-truth distribution. In supervised learning settings such as classification, performance metrics such…

Machine Learning · Computer Science 2026-04-08 Shashaank Aiyer , Yishay Mansour , Shay Moran , Han Shao

Accurate predictions and representations of plant growth patterns in simulated and controlled environments are important for addressing various challenges in plant phenomics research. This review explores various works on state-of-the-art…

Quantitative Methods · Quantitative Biology 2025-07-17 Mohamed Debbagh , Shangpeng Sun , Mark Lefsrud

Providing diagnostic feedback about growth is crucial to formative decisions such as targeted remedial instructions or interventions. This paper proposed a longitudinal higher-order diagnostic classification modeling approach for measuring…

Methodology · Statistics 2018-09-19 Peida Zhan , Hong Jiao , Dandan Liao

Spatial generalized linear mixed models (SGLMMs) are popular for analyzing non-Gaussian spatial data. These models assume a prescribed link function that relates the underlying spatial field with the mean response. There are circumstances,…

Computation · Statistics 2019-01-09 Evangelos Evangelou , Vivekananda Roy

Analyses of biomedical studies often necessitate modeling longitudinal causal effects. The current focus on personalized medicine and effect heterogeneity makes this task even more challenging. Towards this end, structural nested mean…

Methodology · Statistics 2022-07-25 Linbo Wang , Xiang Meng , Thomas S. Richardson , James M. Robins

Probabilistic programming has emerged as a powerful paradigm in statistics, applied science, and machine learning: by decoupling modelling from inference, it promises to allow modellers to directly reason about the processes generating…

Machine Learning · Statistics 2019-06-10 Maria I. Gorinova , Dave Moore , Matthew D. Hoffman