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In optoacoustic (photoacoustic) tomography, several parameters related to tissue and detector features are needed for image formation, but they may not be known a priori. An autofocus (AF) algorithm is generally used to estimate these…

Medical Physics · Physics 2022-03-14 Ludwig Englert , Lucas Riobo , Christine Schonemann , Vasilis Ntziachristos , Juan Aguirre

Fourier ptychography microscopy (FPM), sharing its roots with synthetic aperture technique and phase retrieval method, is a recently developed computational microscopic super-resolution technique. By turning on the light-emitting diode…

Optics · Physics 2021-05-07 G. Zhou , S. Zhang , C. Zheng , T. Li , Y. Hu , Q. Hao

One primary technical challenge in photoacoustic microscopy (PAM) is the necessary compromise between spatial resolution and imaging speed. In this study, we propose a novel application of deep learning principles to reconstruct…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Anthony DiSpirito , Daiwei Li , Tri Vu , Maomao Chen , Dong Zhang , Jianwen Luo , Roarke Horstmeyer , Junjie Yao

A fundamental challenge in endoscopy is how to fabricate a small fiber-optic probe that can achieve comparable function to probes with large, complicated optics (e.g., high resolution and extended depth of focus). To achieve high resolution…

Photoacoustic imaging (PAI) is a promising medical imaging modality providing the spatial resolution of ultrasound (US) imaging and the contrast of pure optical imaging. For linear-array PAI, a beamformer has to be used as the…

Medical Physics · Physics 2018-02-15 Moein Mozaffarzadeh , Yan Yan , Mohammad Mehrmohammadi , Bahador Makkiabadi

In this report, we demonstrate a new principle to improve the resolution of the acoustic microscopy, which is based on the sub-wavelength focusing of acoustic wave passing through an acoustically transparent mesoscale particle. In the…

General Physics · Physics 2017-12-06 I. V. Minin , Q. Tang , S. Bhuyan , J. Hu , O. V. Minin

Photoacoustic imaging (PAI) is a non-invasive imaging modality that detects the ultrasound signal generated from tissue with light excitation. Photoacoustic computed tomography (PACT) uses unfocused large-area light to illuminate the target…

Image and Video Processing · Electrical Eng. & Systems 2022-04-13 Hengrong Lan , Jiali Gong , Fei Gao

As a burgeoning medical imaging method based on hybrid fusion of light and ultrasound, photoacoustic imaging (PAI) has demonstrated high potential in various biomedical applications recently, especially in revealing the functional and…

Signal Processing · Electrical Eng. & Systems 2022-11-21 Tianqu Hu , Zihao Huang , Peng Ge , Feng Gao , Fei Gao

Photoacoustic imaging (PAI) and ultrasound imaging (USI) are important biomedical imaging techniques, due to their unique and complementary advantages in tissue's structure and function visualization. In this Letter, we proposed a coaxial…

Medical Physics · Physics 2024-11-12 Yunhui Jiang , Fan Zhang , Yuwei Zheng , Ruixi Sun , Fei Gao

Acoustoelectric (AE) imaging provides electro-anatomical contrast by mapping the distribution of electric fields in biological tissues, by delivering ultrasound waves which spatially modulate the medium resistivity via the AE effect. The…

Image and Video Processing · Electrical Eng. & Systems 2025-12-17 Wei Yi Oon , Yuchen Tang , Baiqian Qi , Wei-Ning Lee

Photoacoustic image (PAI) quality improvement using a low frequency piezoelectric micromachined ultrasound transducer (PMUT) having the fundamental resonant frequency 1 MHz is being reported. Specifically, three different methods are…

Instrumentation and Detectors · Physics 2022-12-01 Kaustav Roy , Arijit Paramanik , Souradip Paul , Akshay Kalyan , Eshani Sarkar , Anuj Ashok , Rudra Pratap , M Suheshkumar Singh

Acoustic-resolution optoacoustic microscopy (AR-OAM) retrieves anatomical and functional contrast from living tissues at depths not reachable with optical microscopy. The imaging performance of AR-OAM has been advanced with image…

Non-invasive imaging plays a crucial role in diagnosing and studying eye diseases. However, existing photoacoustic ophthalmoscopy (PAOM) techniques in mice have limitations due to handling restrictions, suboptimal optical properties,…

Significance: We proposed a new design of hand-held linear-array photoacoustic (PA) probe which can acquire multi images via motor moving. Moreover, images from different locations are utilized via imaging fusion for SNR enhancement. Aim:…

Medical Physics · Physics 2020-11-09 Yongjian Zhao , Luyao Zhu , Hengrong Lan , Daohuai Jiang , Feng Gao , Fei Gao

Photoacoustic imaging (PAI) is a novel hybrid imaging technique that combines the benefits of both optical and acoustic imaging modalities, which provides functional and molecular optical contrasts of deep tissue. Commonly used ultrasound…

Medical Physics · Physics 2025-09-24 Xiyu Chen , Junxiang Cai , Rui Zheng , Tao Wu , Fei Gao

Photo-acoustic spectroscopy (PAS) is one of the most sensitive non-destructive analysis techniques for gases, fluids and solids. It can operate background-free at any wavelength and is applicable to microscopic and even non-transparent…

Photoacoustic imaging (PAI), is a promising medical imaging technique that provides the high contrast of the optical imaging and the resolution of ultrasound (US) imaging. Among all the methods, Three-dimensional (3D) PAI provides a high…

Signal Processing · Electrical Eng. & Systems 2018-02-27 Roya Paridar , Moein Mozaffarzadeh , Ali Mahloojifar , Mohammadreza Nasiriavanaki , Mahdi Orooji

Photoacoustic tomography (PAT) offers high optical contrast with acoustic imaging depth, making it essential for biomedical applications. While many all-optical systems have been developed to address limitations of ultrasound transducers,…

Optics · Physics 2024-10-11 Taeil Yoon , Hakseok Ko , Jeongmyo Im , Euiheon Chung , Wonshik Choi , Byeong Ha Lee

Photoacoustic Microscopy (PAM) images integrating the advantages of optical contrast and acoustic resolution have been widely used in brain studies. However, there exists a trade-off between scanning speed and image resolution. Compared…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Kai Pan , Linyang Li , Li Lin , Pujin Cheng , Junyan Lyu , Lei Xi , Xiaoyin Tang

Photoacoustic imaging (PAI) is a novel modality in biomedical imaging technology that combines the rich optical contrast with the deep penetration of ultrasound. To date, PAI technology has found applications in various biomedical fields.…

Medical Physics · Physics 2023-09-07 Daohuai Jiang , Luyao Zhu , Shangqing Tong , Yuting Shen , Feng Gao , Fei Gao