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Related papers: Chemical-protein Interaction Extraction via Gaussi…

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Document-Level Biomedical Relation Extraction (Bio-RE) aims to identify relations between biomedical entities within extensive texts, serving as a crucial subfield of biomedical text mining. Existing Bio-RE methods struggle with…

Computation and Language · Computer Science 2025-01-10 Yufei Shang , Yanrong Guo , Shijie Hao , Richang Hong

Peptides play a pivotal role in a wide range of biological activities through participating in up to 40% protein-protein interactions in cellular processes. They also demonstrate remarkable specificity and efficacy, making them promising…

Biomolecules · Quantitative Biology 2024-02-09 Song Yin , Xuenan Mi , Diwakar Shukla

We participated, in the Article Classification and the Interaction Method subtasks (ACT and IMT, respectively) of the Protein-Protein Interaction task of the BioCreative III Challenge. For the ACT, we pursued an extensive testing of…

Quantitative Methods · Quantitative Biology 2011-04-25 Anália Lourenço , Michael Conover , Andrew Wong , Azadeh Nematzadeh , Fengxia Pan , Hagit Shatkay , Luis M. Rocha

Structured chemical reaction information plays a vital role for chemists engaged in laboratory work and advanced endeavors such as computer-aided drug design. Despite the importance of extracting structured reactions from scientific…

Computation and Language · Computer Science 2023-07-06 Ming Zhong , Siru Ouyang , Minhao Jiang , Vivian Hu , Yizhu Jiao , Xuan Wang , Jiawei Han

Background: Protein-protein interaction (PPI) network analyses are highly valuable in deciphering and understanding the intricate organisation of cellular functions. Nevertheless, the majority of available protein-protein interaction…

Molecular Networks · Quantitative Biology 2015-01-08 Oussema Souiai , Fatma Guerfali , Slimane Ben Miled , Christine Brun , Alia Benkahla

Relation extraction (RE) consists in identifying and structuring automatically relations of interest from texts. Recently, BERT improved the top performances for several NLP tasks, including RE. However, the best way to use BERT, within a…

Computation and Language · Computer Science 2020-11-26 Walid Hafiane , Joel Legrand , Yannick Toussaint , Adrien Coulet

In this paper, we consider the statistical analysis of a protein interaction network. We propose a Bayesian model that uses a hierarchy of probabilistic assumptions about the way proteins interact with one another in order to: (i) identify…

Molecular Networks · Quantitative Biology 2007-11-15 Edoardo M Airoldi , David M Blei , Stephen E Fienberg , Eric P Xing

Computational chemistry develops fast in recent years due to the rapid growth and breakthroughs in AI. Thanks for the progress in natural language processing, researchers can extract more fine-grained knowledge in publications to stimulate…

Computation and Language · Computer Science 2019-05-15 Na Pang , Li Qian , Weimin Lyu , Jin-Dong Yang

Protein-protein interactions (PPIs) are of fundamental importance for the human body, and the knowledge of their existence can facilitate very important tasks like drug target developing and therapy design. The high-throughput experiments…

Molecular Networks · Quantitative Biology 2019-10-11 Andrea Moscatelli

Chinese medical question-answer matching is more challenging than the open-domain question answer matching in English. Even though the deep learning method has performed well in improving the performance of question answer matching, these…

Computation and Language · Computer Science 2020-11-30 Xiongtao Cui , Jungang Han

Protein interaction networks are a promising type of data for studying complex biological systems. However, despite the rich information embedded in these networks, they face important data quality challenges of noise and incompleteness…

Molecular Networks · Quantitative Biology 2012-10-29 Gaurav Pandey , Sahil Manocha , Gowtham Atluri , Vipin Kumar

Constructing large-scaled medical knowledge graphs can significantly boost healthcare applications for medical surveillance, bring much attention from recent research. An essential step in constructing large-scale MKG is extracting…

Computer Vision and Pattern Recognition · Computer Science 2021-10-27 Jialun Wu , Yang Liu , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

Motivation: Exploring drug-protein interactions (DPIs) work as a pivotal step in drug discovery. The fast expansion of available biological data enables computational methods effectively assist in experimental methods. Among them, deep…

Machine Learning · Computer Science 2021-02-01 Yifan Wu , Min Gao , Min Zeng , Feiyang Chen , Min Li , Jie Zhang

The protein-protein interactions (PPIs) are crucial for understanding the majority of cellular processes. PPIs play important role in gene transcription regulation, cellular signaling, molecular basis of immune response and more. Moreover,…

Biomolecules · Quantitative Biology 2016-05-31 Maciej Pawel Ciemny , Mateusz Kurcinski , Andrzej Kolinski , Sebastian Kmiecik

This paper focuses on using natural language descriptions to enhance predictive models in the chemistry field. Conventionally, chemoinformatics models are trained with extensive structured data manually extracted from the literature. In…

Computation and Language · Computer Science 2023-12-11 Yujie Qian , Zhening Li , Zhengkai Tu , Connor W. Coley , Regina Barzilay

Nanomaterial-protein interactions (NPI) are pivotal to realizing the therapeutic and diagnostic potential of nanomaterials. Although AI promises to accelerate mechanistic understanding and enable rational nanomaterial design, robust…

Machine Learning · Computer Science 2026-04-29 Hengjie Yu , Kenneth A. Dawson , Haiyun Yang , Shuya Liu , Yan Yan , Yaochu Jin

High-throughput protein interaction detection methods are strongly affected by false positive and false negative results. Focused experiments are needed to complement the large-scale methods by validating previously detected interactions…

Molecular Networks · Quantitative Biology 2007-05-23 Istvan Albert , Reka Albert

Although information extraction and coreference resolution appear together in many applications, most current systems perform them as ndependent steps. This paper describes an approach to integrated inference for extraction and coreference…

Machine Learning · Computer Science 2012-07-19 Ben Wellner , Andrew McCallum , Fuchun Peng , Michael Hay

Complexes of physically interacting proteins constitute fundamental functional units responsible for driving biological processes within cells. A faithful reconstruction of the entire set of complexes is therefore essential to understand…

Molecular Networks · Quantitative Biology 2015-05-21 Sriganesh Srihari , Chern Han Yong , Ashwini Patil , Limsoon Wong

Biomedical event extraction is an information extraction task to obtain events from biomedical text, whose targets include the type, the trigger, and the respective arguments involved in an event. Traditional biomedical event extraction…

Computation and Language · Computer Science 2024-03-20 Pengchao Wu , Xuefeng Li , Jinghang Gu , Longhua Qian , Guodong Zhou
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