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Understanding complex biological macromolecules, especially proteins, is vital for grasping their diverse chemical functions with direct impact in biology and pharmacology. While techniques like X-ray crystallography and cryo-electron…

Biomolecules · Quantitative Biology 2024-04-12 S. H. Mejias , A. L. Cortajarena , R. Mincigrucci , C. Svetina , C. Masciovecchio

Imaging distributions of radioactive sources plays a substantial role in nuclear medicine as well as in monitoring nuclear waste and its deposit. Coded Aperture Imaging has been proposed as an alternative to parallel or pinhole collimators,…

Medical Physics · Physics 2023-01-12 T. Meißner , V. Rozhkov , J. Hesser , W. Nahm , N. Loew

Pulmonary nodule detection plays an important role in lung cancer screening with low-dose computed tomography (CT) scans. It remains challenging to build nodule detection deep learning models with good generalization performance due to…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Yuemeng Li , Yong Fan

Crack Segmentation in industrial concrete surfaces is a challenging task because cracks usually exhibit intricate morphology with slender appearances. Traditional segmentation methods often struggle to accurately locate such cracks, leading…

Computer Vision and Pattern Recognition · Computer Science 2025-01-23 Xianglong Shi , Yunhan Jiang , Xiaoheng Jiang , Mingling Xu , Yang Liu

Identification of critical residues of a protein is actively pursued, since such residues are essential for protein function. We present three ways of recognising critical residues of an example protein, the evolution of which is tracked…

Biomolecules · Quantitative Biology 2025-06-13 Chuqiao Zhang , Sarath Chandra Dantu , Debarghya Mitra , Dalia Chakrabarty

Dual-energy computed tomography (DECT) has been widely used in many applications that need material decomposition. Image-domain methods directly decompose material images from high- and low-energy attenuation images, and thus, are…

Image and Video Processing · Electrical Eng. & Systems 2022-01-25 Zhipeng Li , Yong Long , Il Yong Chun

Recent developments in deep learning-based methods demonstrated its potential to predict the 3D protein structures using inputs such as protein sequences, Cryo-Electron microscopy (Cryo-EM) images of proteins, etc. However, these methods…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Jaydeep Rade , Soumik Sarkar , Anwesha Sarkar , Adarsh Krishnamurthy

Spectral clustering, as a popular tool for data clustering, requires an eigen-decomposition step on a given affinity to obtain the spectral embedding. Nevertheless, such a step suffers from the lack of generalizability and scalability.…

Machine Learning · Computer Science 2025-03-13 Wei He , Shangzhi Zhang , Chun-Guang Li , Xianbiao Qi , Rong Xiao , Jun Guo

The NASA/IPAC Extragalactic Database (NED) is an impressive tool for finding near-exhaustive information on millions of astrophysical objects. Here, we outline a small systematic error that occurs in NED because a low-redshift approximation…

Cosmology and Nongalactic Astrophysics · Physics 2023-01-30 Anthony Carr , Tamara Davis

We present a new method for estimating the Neural Reflectance Field (NReF) of an object from a set of posed multi-view images under unknown lighting. NReF represents 3D geometry and appearance of objects in a disentangled manner, and are…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Xiu Li , Xiao Li , Yan Lu

Determining the three-dimensional structure of proteins and protein complexes at atomic resolution is a fundamental task in structural biology. Over the last decade, remarkable progress has been made using "single particle" cryo-electron…

Numerical Analysis · Mathematics 2017-06-05 Alex Barnett , Leslie Greengard , Andras Pataki , Marina Spivak

Protein inverse folding aims to design an amino acid sequence that will fold into a given backbone structure, serving as a central task in protein design. Two main paradigms have been widely explored. Template-based methods exploit…

Machine Learning · Computer Science 2026-03-17 Yiran Zhu , Changxi Chi , Hongxin Xiang , Wenjie Du , Xiaoqi Wang , Jun Xia

Practical random network coding based schemes for multicast include a header in each packet that records the transformation between the sources and the terminal. The header introduces an overhead that can be significant in certain…

Information Theory · Computer Science 2010-06-03 Shizheng Li , Aditya Ramamoorthy

Deep learning based pipelines for semantic segmentation often ignore structural information available on annotated images used for training. We propose a novel post-processing module enforcing structural knowledge about the objects of…

Computer Vision and Pattern Recognition · Computer Science 2023-08-02 Jérémy Chopin , Jean-Baptiste Fasquel , Harold Mouchère , Rozenn Dahyot , Isabelle Bloch

Two novel reduced dimensionality (RD) experiments -(4,3)D-hNCOcaNH and (4,3)D-hNcoCANH- have been presented here to facilitate the backbone resonance assignment of proteins both in terms of its accuracy and speed. The experiments basically…

Biological Physics · Physics 2015-06-16 Dinesh Kumar

Two-dimensional error-correcting codes, where codewords are represented as $n \times n$ arrays over a $q$-ary alphabet, find important applications in areas such as QR codes, DNA-based storage, and racetrack memories. Among the possible…

Information Theory · Computer Science 2026-02-17 Wenhao Liu , Zhengyi Jiang , Zhongyi Huang , Hanxu Hou

This paper describes the general characteristics of raw data from fiber-fed spectrographs in general and fiber-fed IFUs in particular. The different steps of the data reduction are presented, and the techniques used to address the unusual…

Astrophysics · Physics 2010-11-11 S. F. Sanchez

Compositional representations of the world are a promising step towards enabling high-level scene understanding and efficient transfer to downstream tasks. Learning such representations for complex scenes and tasks remains an open…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Matthew Wallingford , Aditya Kusupati , Alex Fang , Vivek Ramanujan , Aniruddha Kembhavi , Roozbeh Mottaghi , Ali Farhadi

As the number of solved protein structures increases, the opportunities for meta-analysis of this dataset increase too. Protein structures are known to be formed of domains; structural and functional subunits that are often repeated across…

Biomolecules · Quantitative Biology 2018-09-19 William P. Grant , Sebastian E. Ahnert

Motivation: Human cancer is caused by the accumulation of somatic mutations in tumor suppressors and oncogenes within the genome. In the case of oncogenes, recent theory suggests that there are only a few key "driver" mutations responsible…

Genomics · Quantitative Biology 2013-07-16 Gregory Ryslik , Yuwei Cheng , Kei-Hoi Cheung , Yorgo Modis , Hongyu Zhao