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Machine learning techniques used in computer-aided medical image analysis usually suffer from the domain shift problem caused by different distributions between source/reference data and target data. As a promising solution, domain…
Deep learning for medical image classification faces three major challenges: 1) the number of annotated medical images for training are usually small; 2) regions of interest (ROIs) are relatively small with unclear boundaries in the whole…
Effectively representing medical concepts and patients is important for healthcare analytical applications. Representing medical concepts for healthcare analytical tasks requires incorporating medical domain knowledge and prior information…
Image registration is a fundamental medical image analysis task, and a wide variety of approaches have been proposed. However, only a few studies have comprehensively compared medical image registration approaches on a wide range of…
Design patterns are elegant and well-tested solutions to recurrent software development problems. They are the result of software developers dealing with problems that frequently occur, solving them in the same or a slightly adapted way. A…
How should researchers analyze randomized experiments in which the main outcome is latent and measured in multiple ways but each measure contains some degree of error? We first identify a critical study-specific noncomparability problem in…
Process mining offers techniques to exploit event data by providing insights and recommendations to improve business processes. The growing amount of algorithms for process discovery has raised the question of which algorithms perform best…
Foundation models (FMs) have demonstrated strong transferability across medical imaging tasks, yet their clinical utility depends critically on how pretrained representations are adapted to domain-specific data, supervision regimes, and…
World models have emerged as a critical frontier in AI research, aiming to enhance large models by infusing them with physical dynamics and world knowledge. The core objective is to enable agents to understand, predict, and interact with…
Medical imaging datasets usually exhibit domain shift due to the variations of scanner vendors, imaging protocols, etc. This raises the concern about the generalization capacity of machine learning models. Domain generalization (DG), which…
Measuring innovation often relies on context-specific proxies and on expert evaluation. Hence, empirical innovation research is often limited to settings where such data is available. We investigate how large language models (LLMs) can be…
Objective. We propose an approach to reason about goals, obstacles, and to select suitable big data solution architecture that satisfy quality goal preferences and constraints of stakeholders at the presence of the decision outcome…
Deep learning models have revolutionized the field of medical image analysis, due to their outstanding performances. However, they are sensitive to spurious correlations, often taking advantage of dataset bias to improve results for…
Causal inference analysis is the estimation of the effects of actions on outcomes. In the context of healthcare data this means estimating the outcome of counter-factual treatments (i.e. including treatments that were not observed) on a…
Semantic segmentation is an essential component of medical image analysis research, with recent deep learning algorithms offering out-of-the-box applicability across diverse datasets. Despite these advancements, segmentation failures remain…
Fast, gradient-based structural optimization has long been limited to a highly restricted subset of problems -- namely, density-based compliance minimization -- for which gradients can be analytically derived. For other objective functions,…
In this paper, for the first time, we propose an evaluation method for deep learning models that assesses the performance of a model not only in an unseen test scenario, but also in extreme cases of noise, outliers and ambiguous input data.…
The hybrid cloud idea is increasingly gaining momentum because it brings distinct advantages as a hosting platform for complex software systems. However, there are several challenges that need to be surmounted before hybrid hosting can…
Energy systems optimisation models are a leading tool for informing decisions in the energy transition. However, these models often remain opaque, and results are frequently presented without a clear discussion of their epistemic…
Image segmentation is a fundamental problem in computational vision and medical imaging. Designing a generic, automated method that works for various objects and imaging modalities is a formidable task. Instead of proposing a new specific…