English
Related papers

Related papers: Synthetic Controls with Imperfect Pre-Treatment Fi…

200 papers

High-dimensional data acquired from biological experiments such as next generation sequencing are subject to a number of confounding effects. These effects include both technical effects, such as variation across batches from instrument…

Machine Learning · Computer Science 2018-12-11 Kabir Manghnani , Adam Drake , Nathan Wan , Imran Haque

The study of causal effects in the presence of unmeasured spatially varying confounders has garnered increasing attention. However, a general framework for identifiability, which is critical for reliable causal inference from observational…

Methodology · Statistics 2026-02-27 Tommy Tang , Xinran Li , Bo Li

In adaptive clinical trials, the conventional confidence interval (CI) for a treatment effect is prone to undesirable properties such as undercoverage and potential inconsistency with the final hypothesis testing decision. Accordingly, as…

We study the problem of selecting the best heterogeneous treatment effect (HTE) estimator from a collection of candidates in settings where the treatment effect is fundamentally unobserved. We cast estimator selection as a multiple testing…

Machine Learning · Statistics 2025-11-25 Jiayi Guo , Zijun Gao

This paper addresses the problem of computing controllers that are correct by design for safety-critical systems and can provably satisfy (complex) functional requirements. We develop new methods for models of systems subject to both…

Systems and Control · Electrical Eng. & Systems 2022-10-18 Oliver Schön , Birgit van Huijgevoort , Sofie Haesaert , Sadegh Soudjani

This work develops a stochastic model predictive controller~(SMPC) for uncertain linear systems with additive Gaussian noise subject to state and control constraints. The proposed approach is based on the recently developed finite-horizon…

Optimization and Control · Mathematics 2019-11-26 Kazuhide Okamoto , Panagiotis Tsiotras

Several problems in statistics involve the combination of high-variance unbiased estimators with low-variance estimators that are only unbiased under strong assumptions. A notable example is the estimation of causal effects while combining…

Methodology · Statistics 2023-05-25 Michael Oberst , Alexander D'Amour , Minmin Chen , Yuyan Wang , David Sontag , Steve Yadlowsky

Supervised synthetic CT generation from CBCT requires registered training pairs, yet perfect registration between separately acquired scans remains unattainable. This registration bias propagates into trained models and corrupts standard…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lukas Zimmermann , Michael Rauter , Maximilian Schmid , Dietmar Georg , Barbara Knäusl

Uncertainty quantification of causal effects is crucial for safety-critical applications such as personalized medicine. A powerful approach for this is conformal prediction, which has several practical benefits due to model-agnostic…

Machine Learning · Computer Science 2026-02-04 Maresa Schröder , Dennis Frauen , Jonas Schweisthal , Konstantin Heß , Valentyn Melnychuk , Stefan Feuerriegel

In empirical studies with time-to-event outcomes, investigators often leverage observational data to conduct causal inference on the effect of exposure when randomized controlled trial data is unavailable. Model misspecification and lack of…

Methodology · Statistics 2023-05-05 Shenbo Xu , Bang Zheng , Bowen Su , Stan Finkelstein , Roy Welsch , Kenney Ng , Ioanna Tzoulaki , Zach Shahn

The heterogeneous treatment effect plays a crucial role in precision medicine.There is evidence that real-world data, even subject to biases, can be employed as supplementary evidence for randomized clinical trials to improve the…

Methodology · Statistics 2025-09-04 Guangcai Mao , Shu Yang , Xiaofei Wang

Simulation-based calibration (SBC) is a method for validating inference algorithms and model implementations through repeated inference on data simulated from a generative model. For a model to be generative, one must specify proper priors.…

Methodology · Statistics 2025-05-26 Luna Fazio , Maximilian Scholz , Javier Enrique Aguilar , Paul-Christian Bürkner

This paper examines methods of causal inference based on groupwise matching when we observe multiple large groups of individuals over several periods. We formulate causal inference validity through a generalized matching condition,…

Econometrics · Economics 2026-03-24 Ratzanyel Rincón , Kyungchul Song

Proximal causal inference (PCI) has emerged as a promising framework for identifying and estimating causal effects in the presence of unobserved confounders. While many traditional causal inference methods rely on the assumption of no…

Recently, we and several other authors have written about the possibilities of using stochastic approximation techniques for fitting variational approximations to intractable Bayesian posterior distributions. Naive implementations of…

Computation · Statistics 2014-01-14 Tim Salimans , David A. Knowles

Estimating individualized treatment effects (ITEs) from observational data is crucial for decision-making. In order to obtain unbiased ITE estimates, a common assumption is that all confounders are observed. However, in practice, it is…

Machine Learning · Statistics 2021-12-07 Milan Kuzmanovic , Tobias Hatt , Stefan Feuerriegel

In a unified framework, we provide estimators and confidence bands for a variety of treatment effects when the outcome of interest, typically a duration, is subjected to right censoring. Our methodology accommodates average, distributional,…

Methodology · Statistics 2017-10-04 Pedro H. C. Sant'Anna

We propose a generalization of the synthetic control and interventions methods to the setting with dynamic treatment effects. We consider the estimation of unit-specific treatment effects from panel data collected under a general treatment…

Econometrics · Economics 2025-10-03 Anish Agarwal , Sukjin Han , Dwaipayan Saha , Vasilis Syrgkanis , Haeyeon Yoon

Imbalanced classification often causes standard training procedures to prioritize the majority class and perform poorly on rare but important cases. A classic and widely used remedy is to augment the minority class with synthetic samples,…

Machine Learning · Statistics 2026-03-10 Zhengchi Ma , Anru R. Zhang

We consider the problem of efficient inference of the Average Treatment Effect in a sequential experiment where the policy governing the assignment of subjects to treatment or control can change over time. We first provide a central limit…

Machine Learning · Statistics 2024-03-05 Thomas Cook , Alan Mishler , Aaditya Ramdas