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Lung nodule detection is a class imbalanced problem because nodules are found with much lower frequency than non-nodules. In the class imbalanced problem, conventional classifiers tend to be overwhelmed by the majority class and ignore the…

Computer Vision and Pattern Recognition · Computer Science 2016-11-23 Masaharu Sakamoto , Hiroki Nakano

Medical images from different healthcare centers exhibit varied data distributions, posing significant challenges for adapting lung nodule detection due to the domain shift between training and application phases. Traditional unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2024-08-05 Haifeng Zhao , Lixiang Jiang , Leilei Ma , Dengdi Sun , Yanping Fu

Accurate lung lesion segmentation from Computed Tomography (CT) images is crucial to the analysis and diagnosis of lung diseases such as COVID-19 and lung cancer. However, the smallness and variety of lung nodules and the lack of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Changwei Wang , Rongtao Xu , Shibiao Xu , Weiliang Meng , Jun Xiao , Xiaopeng Zhang

Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Hanxiao Zhang , Liang Chen , Xiao Gu , Minghui Zhang , Yulei Qin , Feng Yao , Zhexin Wang , Yun Gu , Guang-Zhong Yang

Purpose: Lung nodules have very diverse shapes and sizes, which makes classifying them as benign/malignant a challenging problem. In this paper, we propose a novel method to predict the malignancy of nodules that have the capability to…

Computer Vision and Pattern Recognition · Computer Science 2019-04-24 Mundher Al-Shabi , Boon Leong Lan , Wai Yee Chan , Kwan-Hoong Ng , Maxine Tan

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu

Purpose: Lung nodule segmentation, i.e., the algorithmic delineation of the lung nodule surface, is a fundamental component of computational nodule analysis pipelines. We propose a new method for segmentation that is a machine learning…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Matthew C Hancock , Jerry F Magnan

Lung cancer is the primary cause of cancer-related mortality, claiming approximately 1.79 million lives globally in 2020, with an estimated 2.21 million new cases diagnosed within the same period. Among these, Non-Small Cell Lung Cancer…

Quantitative Methods · Quantitative Biology 2024-02-16 Mahtab Darvish , Ryan Trask , Patrick Tallon , Mélina Khansari , Lei Ren , Michelle Hershman , Bardia Yousefi

Lung cancer is a primary contributor to cancer-related mortality globally, highlighting the necessity for precise early detection of pulmonary nodules through low-dose CT (LDCT) imaging. Deep learning methods have improved nodule detection…

Quantitative Methods · Quantitative Biology 2025-12-10 Fateme Mobini , Mohammad Reza Hedyehzadeh , Mahdi Yousefi

Content-based retrieval supports a radiologist decision making process by presenting the doctor the most similar cases from the database containing both historical diagnosis and further disease development history. We present a deep…

Information Retrieval · Computer Science 2020-07-15 Ilia Kravets , Tal Heletz , Hayit Greenspan

Pulmonary nodule detection plays an important role in lung cancer screening with low-dose computed tomography (CT) scans. It remains challenging to build nodule detection deep learning models with good generalization performance due to…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Yuemeng Li , Yong Fan

Background and Objective: Early detection of lung cancer is crucial as it has high mortality rate with patients commonly present with the disease at stage 3 and above. There are only relatively few methods that simultaneously detect and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-18 Kelvin Shak , Mundher Al-Shabi , Andrea Liew , Boon Leong Lan , Wai Yee Chan , Kwan Hoong Ng , Maxine Tan

Tuberculosis (TB) is still recognized as one of the leading causes of death worldwide. Recent advances in deep learning (DL) have shown to enhance radiologists' ability to interpret chest X-ray (CXR) images accurately and with fewer errors,…

Image and Video Processing · Electrical Eng. & Systems 2023-09-06 Daniel Capellán-Martín , Juan J. Gómez-Valverde , David Bermejo-Peláez , María J. Ledesma-Carbayo

Lung cancer remains one of the leading causes of cancer-related mortality worldwide, with early and accurate diagnosis playing a pivotal role in improving patient outcomes. Automated detection of pulmonary nodules in computed tomography…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Abhinav Roy , Bhavesh Gyanchandani , Aditya Oza

Due to silence in early stages, lung cancer has been one of the most leading causes of mortality in cancer patients world-wide. Moreover, major symptoms of lung cancer are hard to differentiate with other respiratory disease symptoms such…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Daeyoung Kim

Lung nodule proposals generation is the primary step of lung nodule detection and has received much attention in recent years . In this paper, we first construct a model of 3-dimension Convolutional Neural Network (3D CNN) to generate lung…

Computer Vision and Pattern Recognition · Computer Science 2018-02-08 Hui Wu , Matrix Yao , Albert Hu , Gaofeng Sun , Xiaokun Yu , Jian Tang

Collectively, lung cancer, breast cancer and melanoma was diagnosed in over 535,340 people out of which, 209,400 deaths were reported [13]. It is estimated that over 600,000 people will be diagnosed with these forms of cancer in 2015. Most…

Machine Learning · Computer Science 2015-09-29 Mohnish Chakravarti , Tanay Kothari

Accurate lung nodule detection for computed tomography (CT) scan imagery is challenging in real-world settings due to the sparse occurrence of nodules and similarity to other anatomical structures. In a typical positive case, nodules may…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Hooman Ramezani , Dionne Aleman , Daniel Létourneau

Lung cancer is a leading cause of death worldwide. Early-stage detection of lung cancer is essential for a more favorable prognosis. Radiogenomics is an emerging discipline that combines medical imaging and genomics features for modeling…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Ivo Gollini Navarrete , Mohammad Yaqub

Invasive ductal carcinoma is a prevalent, potentially deadly disease associated with a high rate of morbidity and mortality. Its malignancy is the second leading cause of death from cancer in women. The mammogram is an extremely useful…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Rushabh Patel