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Each day, anti-virus companies receive tens of thousands samples of potentially harmful executables. Many of the malicious samples are variations of previously encountered malware, created by their authors to evade pattern-based detection.…

Cryptography and Security · Computer Science 2010-08-27 Joris Kinable , Orestis Kostakis

Voice Assistant (VA) in smartphones has become very popular with millions of users nowadays. A key trend is the rise of custom VA embedding, which enables users to perform the customized tasks of their favorite app through voice control.…

Software Engineering · Computer Science 2024-07-26 Garrett Weaver , Xue Qin

The standardization of clinical data elements (CDEs) aims to ensure consistent and comprehensive patient information across various healthcare systems. Existing methods often falter when standardizing CDEs of varying representation and…

Information Retrieval · Computer Science 2025-05-08 Komal Gilani , Marlo Verket , Christof Peters , Michel Dumontier , Hans-Peter Brunner-La Rocca , Visara Urovi

We develop a cross-platform open-source Java application (BACOM2) with graphic user interface (GUI), and users also can use a XML file to set the parameters of algorithm model, file paths and the dataset of paired samples. BACOM2 implements…

Genomics · Quantitative Biology 2015-05-19 Yi Fu , Jun Ruan , Guoqiang Yu , Douglas A. Levine , Niya Wang , Ie-Ming Shih , Zhen Zhang , Robert Clarke , Yue Wang

The ever-increasing number of Android devices and the accelerated evolution of malware, reaching over 35 million samples by 2024, highlight the critical importance of effective detection methods. Attackers are now using Artificial…

Cryptography and Security · Computer Science 2025-11-26 Angelo Gaspar Diniz Nogueira , Kayua Oleques Paim , Hendrio Bragança , Rodrigo Brandão Mansilha , Diego Kreutz

Variability-aware metrics are designed to measure qualitative aspects of software product lines. As we identified in a prior SLR \cite{El-SharkawyYamagishi-EichlerSchmid19}, there exist already many metrics that address code or variability…

Software Engineering · Computer Science 2021-10-20 Sascha El-Sharkawy , Adam Krafczyk , Klaus Schmid

Next-generation sequencing techniques have facilitated a large scale analysis of human genetic variation. Despite the advances in sequencing speeds, the computational discovery of structural variants is not yet standard. It is likely that…

The genes that encode the targets of most therapies do not have rare variants with large-effect or common variants with moderate effects on the biomarker reflecting the pharmacologic action of the corresponding therapy. Therefore, providing…

Quantitative Methods · Quantitative Biology 2020-07-28 B. A. Ference , G. Davey Smith , M. V. Holmes , A. L. Catapano , K. K. Ray , S. J. Nicholls

With the rapid advancements in cancer research, the information that is useful for characterizing disease, staging tumors, and creating treatment and survivorship plans has been changing at a pace that creates challenges when physicians try…

We present our vision for developing an automated tool capable of translating visual properties observed in Machine Learning (ML) visualisations into Python assertions. The tool aims to streamline the process of manually verifying these…

Software Engineering · Computer Science 2024-01-17 Arumoy Shome , Luis Cruz , Arie van Deursen

In recent years, many mammographic image analysis methods have been introduced for improving cancer classification tasks. Two major issues of mammogram classification tasks are leveraging multi-view mammographic information and…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Thanh-Huy Nguyen , Quang Hien Kha , Thai Ngoc Toan Truong , Ba Thinh Lam , Ba Hung Ngo , Quang Vinh Dinh , Nguyen Quoc Khanh Le

Clinical pathways are specialized healthcare plans that model patient treatment procedures. They are developed to provide criteria-based progression and standardize patient treatment, thereby improving care, reducing resource use, and…

Machine Learning · Computer Science 2025-12-04 Francesco Vitale , Nicola Mazzocca

Metagenomic profiling is challenging in part because of the highly uneven sampling of the tree of life by genome sequencing projects and the limitations imposed by performing phylogenetic inference at fixed taxonomic ranks. We present the…

Genomics · Quantitative Biology 2016-02-18 David Koslicki , Daniel Falush

In order to identify clusters of objects with features transformed by unknown affine transformations, we develop a Bayesian cluster process which is invariant with respect to certain linear transformations of the feature space and able to…

Methodology · Statistics 2016-12-01 Hsin-Hsiung Huang , Jie Yang

Summarization is a challenging problem, and even more challenging is to manually create, correct, and evaluate the summaries. The severity of the problem grows when the inputs are multi-party dialogues in a meeting setup. To facilitate the…

Computation and Language · Computer Science 2022-05-12 Peter Polák , Muskaan Singh , Anna Nedoluzhko , Ondřej Bojar

Name disambiguation -- a fundamental problem in online academic systems -- is now facing greater challenges with the increasing growth of research papers. For example, on AMiner, an online academic search platform, about 10% of names own…

Information Retrieval · Computer Science 2023-06-07 Bo Chen , Jing Zhang , Fanjin Zhang , Tianyi Han , Yuqing Cheng , Xiaoyan Li , Yuxiao Dong , Jie Tang

RNA-Seq technology allows for studying the transcriptional state of the cell at an unprecedented level of detail. Beyond quantification of whole-gene expression, it is now possible to disentangle the abundance of individual alternatively…

Genomics · Quantitative Biology 2012-10-11 Barbara Rakitsch , Christoph Lippert , Hande Topa , Karsten Borgwardt , Antti Honkela , Oliver Stegle

In light of the continuous transmission and evolution of SARS-CoV-2 coupled with a significant decline in clinical testing, there is a pressing need for scalable, cost-effective, long-term, passive surveillance tools to effectively monitor…

Summary: We present needLR, a structural variant (SV) annotation tool that can be used for filtering and prioritization of candidate pathogenic SVs from long-read sequencing data using population allele frequencies, annotations for genomic…

Genomics · Quantitative Biology 2025-12-10 Jonas A. Gustafson , Jiadong Lin , Evan E. Eichler , Danny E. Miller

Clinical notes hold rich yet unstructured details about diagnoses, treatments, and outcomes that are vital to precision medicine but hard to exploit at scale. We introduce a method that represents each patient as a matrix built from…

Machine Learning · Computer Science 2026-01-13 Petr Zelina , Marko Řeháček , Jana Halámková , Lucia Bohovicová , Martin Rusinko , Vít Nováček