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Spatio-temporal systems exhibiting multi-scale behaviour are common in applications ranging from cyber-physical systems to systems biology, yet they present formidable challenges for computational modelling and analysis. Here we consider a…

Quantitative Methods · Quantitative Biology 2019-02-01 Michalis Michaelides , Jane Hillston , Guido Sanguinetti

The use of mutual information as a similarity measure in agglomerative hierarchical clustering (AHC) raises an important issue: some correction needs to be applied for the dimensionality of variables. In this work, we formulate the decision…

Machine Learning · Statistics 2016-08-07 Guillaume Marrelec , Arnaud Messé , Pierre Bellec

Spatial transcriptomics measures the expression of thousands of genes in a tissue sample while preserving its spatial structure. This class of technologies has enabled the investigation of the spatial variation of gene expressions and their…

Methodology · Statistics 2025-10-23 Andrea Sottosanti , Davide Risso , Francesco Denti

Online sampling-supported visual analytics is increasingly important, as it allows users to explore large datasets with acceptable approximate answers at interactive rates. However, existing online spatiotemporal sampling techniques are…

Unsupervised clustering of curves according to their shapes is an important problem with broad scientific applications. The existing model-based clustering techniques either rely on simple probability models (e.g., Gaussian) that are not…

Machine Learning · Statistics 2015-04-03 Zhengwu Zhang , Debdeep Pati , Anuj Srivastava

Estimating causal effects from large experimental and observational data has become increasingly prevalent in both industry and research. The bootstrap is an intuitive and powerful technique used to construct standard errors and confidence…

Methodology · Statistics 2023-02-07 Matthew Kosko , Lin Wang , Michele Santacatterina

In environmental science applications, extreme events frequently exhibit a complex spatio-temporal structure, which is difficult to describe flexibly and estimate in a computationally efficient way using state-of-art parametric…

Methodology · Statistics 2022-12-22 Marco Oesting , Raphaël Huser

Spatio-temporal clustering occupies an established role in various fields dealing with geospatial analysis, spanning from healthcare analysis to environmental science. One major challenge are applications in which cluster assignments are…

Computation · Statistics 2023-11-09 Ben Moews , Antonia Gieschen

We study statistical and computational limits of clustering when the means of the centres are sparse and their dimension is possibly much larger than the sample size. Our theoretical analysis focuses on the model $X_i = z_i \theta +…

Statistics Theory · Mathematics 2021-03-23 Matthias Löffler , Alexander S. Wein , Afonso S. Bandeira

Statistical multispecies models of multiarea marine ecosystems use a variety of data sources to estimate parameters using composite or weighted likelihood functions with associated weighting issues and questions on how to obtain variance…

Applications · Statistics 2012-02-16 Lorna Taylor , Verena M. Trenkel , Vojtech Kupca , Gunnar Stefansson

Our method extends the application of random spanning trees to cases where the response variable belongs to the exponential family, making it suitable for a wide range of real-world scenarios, including non-Gaussian likelihoods. The…

Methodology · Statistics 2024-07-18 Ruiman Zhong , Erick A. Chacón-Montalván , Paula Moraga

We prove the validity of using subsampling method for inference under a two-way clustered panel in which the time effects are serially correlated. Subsamples should be drawn without replacement from randomly partitioned individual index set…

Econometrics · Economics 2026-05-01 Haonan Miao

Quality by design in pharmaceutical manufacturing hinges on computational methods and tools that are capable of accurate quantitative prediction of the design space. This paper investigates Bayesian approaches to design space…

Bayesian model-based spatial clustering methods are widely used for their flexibility in estimating latent clusters with an unknown number of clusters while accounting for spatial proximity. Many existing methods are designed for clustering…

Methodology · Statistics 2025-08-13 Kun Huang , Huiyan Sang

Accurate estimates of subnational health and demographic indicators are critical for informing health policy decisions. Many countries collect relevant data using complex household surveys, but when data are limited, direct survey weighted…

Methodology · Statistics 2022-09-07 Peter A. Gao , Jon Wakefield

A simple model to study subspace clustering is the high-dimensional $k$-Gaussian mixture model where the cluster means are sparse vectors. Here we provide an exact asymptotic characterization of the statistically optimal reconstruction…

Machine Learning · Statistics 2023-04-04 Luca Pesce , Bruno Loureiro , Florent Krzakala , Lenka Zdeborová

On the basis of the dynamical interpretation of Monte Carlo simulations, we discuss the relation of the equilibrium relaxation time, the susceptibility and the statistical error. We introduce a new quantity called {\it the statistical…

Condensed Matter · Physics 2007-05-23 Macoto Kikuchi , Nobuyasu Ito , Yutaka Okabe

The health impact of long-term exposure to air pollution is now routinely estimated using spatial ecological studies, due to the recent widespread availability of spatial referenced pollution and disease data. However, this areal unit study…

Applications · Statistics 2014-12-16 Duncan Lee , Christophe Sarran

We propose Bayesian model averaging (BMA) as a method for postprocessing the results of model-based clustering. Given a number of competing models, appropriate model summaries are averaged, using the posterior model probabilities, instead…

Computation · Statistics 2015-07-01 Niamh Russell , Thomas Brendan Murphy , Adrian E Raftery

The effect of spatial correlations on the spread of infectious diseases was investigated using a stochastic SIR (Susceptible-Infective-Recovered) model on complex networks. It was found that in addition to the reduction of the effective…

Populations and Evolution · Quantitative Biology 2007-05-23 J. Verdasca , M. M. Telo da Gama , A. Nunes , N. R. Bernardino , J. M. Pacheco , M. C. Gomes
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