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In this paper we propose a modified cross correlation method to align images from the same class in single-particle electron microscopy of highly non-spherical structures. In this new method, First we coarsely align projection images, and…

Quantitative Methods · Quantitative Biology 2018-12-26 Wooram Park , Gregory S. Chirikjian

The most established method of reconstructing neural circuits from animals involves slicing tissue very thin, then taking mosaics of electron microscope (EM) images. To trace neurons across different images and through different sections,…

Quantitative Methods · Quantitative Biology 2013-04-23 Louis K. Scheffer , Bill Karsh , Shiv Vitaladevun

We develop a primal-dual algorithm that allows for one-step inversion of spectral CT transmission photon counts data to a basis map decomposition. The algorithm allows for image constraints to be enforced on the basis maps during the…

Medical Physics · Physics 2016-05-04 Rina Foygel Barber , Emil Y. Sidky , Taly Gilat Schmidt , Xiaochuan Pan

Deep learning-based reconstruction of positron emission tomography(PET) data has gained increasing attention in recent years. While these methods achieve fast reconstruction,concerns remain regarding quantitative accuracy and the presence…

Computed tomography is a method for synthesizing volumetric or cross-sectional images of an object from a collection of projections. Popular reconstruction methods for computed tomography are based on idealized models and assumptions that…

Numerical Analysis · Mathematics 2022-03-03 Frederik H. Pedersen , Jakob S. Jørgensen , Martin S. Andersen

Image quality of PET reconstructions is degraded by subject motion occurring during the acquisition. MR-based motion correction approaches have been studied for PET/MR scanners and have been successful at capturing regular motion patterns,…

Medical image segmentation has been widely recognized as a pivot procedure for clinical diagnosis, analysis, and treatment planning. However, the laborious and expensive annotation process lags down the speed of further advances.…

Computer Vision and Pattern Recognition · Computer Science 2022-05-02 Zhuowei Li , Zihao Liu , Zhiqiang Hu , Qing Xia , Ruiqin Xiong , Shaoting Zhang , Dimitris Metaxas , Tingting Jiang

This paper presents a novel hierarchical Bayesian model for unbiased atlas building with subject-specific regularizations of image registration. We develop an atlas construction process that automatically selects parameters to control the…

Computer Vision and Pattern Recognition · Computer Science 2021-07-14 Jian Wang , Miaomiao Zhang

The volume estimation of brain regions from MRI data is a key problem in many clinical applications, where the acquisition of data at high spatial resolution is desirable. While parallel MRI and constrained image reconstruction algorithms…

Image and Video Processing · Electrical Eng. & Systems 2021-05-20 Aniket Pramanik , Xiaodong Wu , Mathews Jacob

To facilitate a prospective estimation of CT effective dose and risk minimization process, a prospective spatial dose estimation and the known anatomical structures are expected. To this end, a CT reconstruction method is required to…

Image and Video Processing · Electrical Eng. & Systems 2024-01-24 Chang Liu , Laura Klein , Yixing Huang , Edith Baader , Michael Lell , Marc Kachelrieß , Andreas Maier

We present a novel variational approach to image restoration (e.g., denoising, inpainting, labeling) that enables to complement established variational approaches with a histogram-based prior enforcing closeness of the solution to some…

Optimization and Control · Mathematics 2013-07-18 Paul Swoboda , Christoph Schnörr

Segmenting anatomical structures in medical images has been successfully addressed with deep learning methods for a range of applications. However, this success is heavily dependent on the quality of the image that is being segmented. A…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Ilkay Oksuz , James R. Clough , Bram Ruijsink , Esther Puyol Anton , Aurelien Bustin , Gastao Cruz , Claudia Prieto , Andrew P. King , Julia A. Schnabel

Parallel imaging techniques reduce magnetic resonance imaging (MRI) scan time but image quality degrades as the acceleration factor increases. In clinical practice, conservative acceleration factors are chosen because no mechanism exists to…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Ilias I. Giannakopoulos , Lokesh B Gautham Muthukumar , Yvonne W. Lui , Riccardo Lattanzi

Previous methods decompose the blind super-resolution (SR) problem into two sequential steps: \textit{i}) estimating the blur kernel from given low-resolution (LR) image and \textit{ii}) restoring the SR image based on the estimated kernel.…

Computer Vision and Pattern Recognition · Computer Science 2021-05-17 Zhengxiong Luo , Yan Huang , Shang Li , Liang Wang , Tieniu Tan

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

Medical Physics · Physics 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

PET super-resolution is highly under-constrained because paired multi-resolution scans from the same subject are rarely available, and effective resolution is determined by scanner-specific physics (e.g., PSF, detector geometry, and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Liutao Yang , Zi Wang , Peiyuan Jing , Xiaowen Wang , Javier A. Montoya-Zegarra , Kuangyu Shi , Daoqiang Zhang , Guang Yang

We consider reconstructing multi-channel images from measurements performed by photon-counting and energy-discriminating detectors in the setting of multi-spectral X-ray computed tomography (CT). Our aim is to exploit the strong structural…

Numerical Analysis · Mathematics 2021-03-11 Lukas Kiefer , Stefania Petra , Martin Storath , Andreas Weinmann

Applying standard algorithms to sparse data problems in photoacoustic tomography (PAT) yields low-quality images containing severe under-sampling artifacts. To some extent, these artifacts can be reduced by iterative image reconstruction…

Numerical Analysis · Mathematics 2024-12-20 Stephan Antholzer , Johannes Schwab , Robert Nuster , Markus Haltmeier

We solve the analysis sparse coding problem considering a combination of convex and non-convex sparsity promoting penalties. The multi-penalty formulation results in an iterative algorithm involving proximal-averaging. We then unfold the…

The development of computed tomography (CT) image reconstruction methods that significantly reduce patient radiation exposure while maintaining high image quality is an important area of research in low-dose CT (LDCT) imaging. We propose a…

Machine Learning · Statistics 2019-06-14 Xuehang Zheng , Saiprasad Ravishankar , Yong Long , Jeffrey A. Fessler
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