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Deep learning has provided new ways of manipulating, processing and analyzing data. It sometimes may achieve results comparable to, or surpassing human expert performance, and has become a source of inspiration in the era of artificial…

Recent advances in machine learning (ML) have expedited retrosynthesis research by assisting chemists to design experiments more efficiently. However, all ML-based methods consume substantial amounts of paired training data (i.e., chemical…

Machine Learning · Computer Science 2024-02-02 Xu Zhang , Yiming Mo , Wenguan Wang , Yi Yang

Optimal designs are usually model-dependent and likely to be sub-optimal if the postulated model is not correctly specified. In practice, it is common that a researcher has a list of candidate models at hand and a design has to be found…

Statistics Theory · Mathematics 2023-03-29 Mingyao Ai , Holger Dette , Zhengfu Liu , Jun Yu

Optimal motion planning involves obstacles avoidance where path planning is the key to success in optimal motion planning. Due to the computational demands, most of the path planning algorithms can not be employed for real-time based…

Robotics · Computer Science 2022-02-15 Geesara Kulathunga

This paper presents a novel approach to root cause attribution of delivery risks within supply chains by integrating causal discovery with reinforcement learning. As supply chains become increasingly complex, traditional methods of root…

Artificial Intelligence · Computer Science 2025-06-12 Minheng Xiao

We address a core problem of computer vision: Detection and description of 2D feature points for image matching. For a long time, hand-crafted designs, like the seminal SIFT algorithm, were unsurpassed in accuracy and efficiency. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2020-03-23 Aritra Bhowmik , Stefan Gumhold , Carsten Rother , Eric Brachmann

Quadratic programming is a workhorse of modern nonlinear optimization, control, and data science. Although regularized methods offer convergence guarantees under minimal assumptions on the problem data, they can exhibit the slow…

Optimization and Control · Mathematics 2026-05-18 Jeremy Bertoncini , Alberto De Marchi , Matthias Gerdts , Simon Gottschalk

From out-competing grandmasters in chess to informing high-stakes healthcare decisions, emerging methods from artificial intelligence are increasingly capable of making complex and strategic decisions in diverse, high-dimensional, and…

Computers and Society · Computer Science 2024-03-05 Melissa Chapman , Lily Xu , Marcus Lapeyrolerie , Carl Boettiger

Machine learning with artificial neural networks is revolutionizing science. The most advanced challenges require discovering answers autonomously. This is the domain of reinforcement learning, where control strategies are improved…

Quantum Physics · Physics 2018-10-03 Thomas Fösel , Petru Tighineanu , Talitha Weiss , Florian Marquardt

Current pharmaceutical formulation development still strongly relies on the traditional trial-and-error approach by individual experiences of pharmaceutical scientists, which is laborious, time-consuming and costly. Recently, deep learning…

Machine Learning · Computer Science 2018-12-05 Yilong Yang , Zhuyifan Ye , Yan Su , Qianqian Zhao , Xiaoshan Li , Defang Ouyang

In agent control issues, the idea of combining reinforcement learning and planning has attracted much attention. Two methods focus on micro and macro action respectively. Their advantages would show together if there is a good cooperation…

Artificial Intelligence · Computer Science 2020-03-20 Xuerun Chen

Predicting monomer reactivity ratios is crucial for controlling monomer sequence distribution in copolymers and their properties. Traditional experimental methods of determining reactivity ratios are time-consuming and resource-intensive,…

Chemical Physics · Physics 2025-12-24 Habibollah Safari , Mona Bavarian

Reliably predicting the products of chemical reactions presents a fundamental challenge in synthetic chemistry. Existing machine learning approaches typically produce a reaction product by sequentially forming its subparts or intermediate…

Chemical Physics · Physics 2021-06-16 Hangrui Bi , Hengyi Wang , Chence Shi , Connor Coley , Jian Tang , Hongyu Guo

Retrosynthesis is the process of determining the set of reactant molecules that can react to form a desired product. Semi-template-based retrosynthesis methods, which imitate the reverse logic of synthesis reactions, first predict the…

Machine Learning · Computer Science 2024-04-01 Frazier N. Baker , Ziqi Chen , Daniel Adu-Ampratwum , Xia Ning

The use of artificial intelligence in supply chain forecasting has attracted many scientific studies for several decades. However, the process of selecting an appropriate forecasting solution becomes a daunting task. This complexity arises…

Machine Learning · Computer Science 2026-05-07 Bilel Abderrahmane Benziane , Benoit Lardeux , Ayoub Mcharek , Maher Jridi

Process synthesis experiences a disruptive transformation accelerated by digitization and artificial intelligence. We propose a reinforcement learning algorithm for chemical process design based on a state-of-the-art actor-critic logic. Our…

Machine Learning · Computer Science 2024-01-17 Laura Stops , Roel Leenhouts , Qinghe Gao , Artur M. Schweidtmann

Can machine learning help us make better decisions about a changing planet? In this paper, we illustrate and discuss the potential of a promising corner of machine learning known as _reinforcement learning_ (RL) to help tackle the most…

Machine Learning · Computer Science 2021-06-16 Marcus Lapeyrolerie , Melissa S. Chapman , Kari E. A. Norman , Carl Boettiger

In this review, we highlight recent developments in the application of machine learning for molecular modeling and simulation. After giving a brief overview of the foundations, components, and workflow of a typical supervised learning…

Data Analysis, Statistics and Probability · Physics 2019-02-21 Mojtaba Haghighatlari , Johannes Hachmann

While contemporary reinforcement learning research and applications have embraced policy gradient methods as the panacea of solving learning problems, value-based methods can still be useful in many domains as long as we can wrangle with…

Machine Learning · Computer Science 2024-07-16 Ashwin Ramaswamy , Ransalu Senanayake

Learning-based approaches for solving large sequential decision making problems have become popular in recent years. The resulting agents perform differently and their characteristics depend on those of the underlying learning approach.…

Machine Learning · Computer Science 2020-08-04 Timo P. Gros , Daniel Höller , Jörg Hoffmann , Verena Wolf