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There has been a current trend in reinforcement learning for healthcare literature, where in order to prepare clinical datasets, researchers will carry forward the last results of the non-administered test known as the…

Machine Learning · Computer Science 2020-06-30 Rui Aguiar , Nikka Mofid , Hyunji Alex Nam

Extracting actionable insight from Electronic Health Records (EHRs) poses several challenges for traditional machine learning approaches. Patients are often missing data relative to each other; the data comes in a variety of modalities,…

Machine Learning · Computer Science 2018-11-13 Brandon Malone , Alberto Garcia-Duran , Mathias Niepert

With the widespread of machine learning models for healthcare applications, there is increased interest in building applications for personalized medicine. Despite the plethora of proposed research for personalized medicine, very few focus…

Machine Learning · Computer Science 2024-02-27 Ghadeer O. Ghosheh , Jin Li , Tingting Zhu

Machine learning risks reinforcing biases present in data and, as we argue in this work, in what is absent from data. In healthcare, societal and decision biases shape patterns in missing data, yet the algorithmic fairness implications of…

Artificial Intelligence · Computer Science 2025-03-19 Vincent Jeanselme , Maria De-Arteaga , Zhe Zhang , Jessica Barrett , Brian Tom

Electronic health record (EHR) data has emerged as a valuable resource for analyzing patient health status. However, the prevalence of missing data in EHR poses significant challenges to existing methods, leading to spurious correlations…

Machine Learning · Computer Science 2024-05-16 Zhihao Yu , Xu Chu , Yujie Jin , Yasha Wang , Junfeng Zhao

We demonstrate a simple strategy to cope with missing data in sequential inputs, addressing the task of multilabel classification of diagnoses given clinical time series. Collected from the pediatric intensive care unit (PICU) at Children's…

Machine Learning · Computer Science 2016-11-14 Zachary C. Lipton , David C. Kale , Randall Wetzel

This study investigates the impact of masking strategies on time series imputation models in healthcare settings. While current approaches predominantly rely on random masking for model evaluation, this practice fails to capture the…

Machine Learning · Computer Science 2025-02-05 Linglong Qian , Yiyuan Yang , Wenjie Du , Jun Wang , Richard Dobsoni , Zina Ibrahim

The current mode of use of Electronic Health Record (EHR) elicits text redundancy. Clinicians often populate new documents by duplicating existing notes, then updating accordingly. Data duplication can lead to a propagation of errors,…

Computation and Language · Computer Science 2023-02-28 Thomas Searle , Zina Ibrahim , James Teo , Richard JB Dobson

Electronic health records (EHR) consist of longitudinal clinical observations portrayed with sparsity, irregularity, and high-dimensionality, which become major obstacles in drawing reliable downstream clinical outcomes. Although there…

Machine Learning · Computer Science 2020-11-17 Ahmad Wisnu Mulyadi , Eunji Jun , Heung-Il Suk

Health economic evaluations based on patient-level data collected alongside clinical trials~(e.g. health related quality of life and resource use measures) are an important component of the process which informs resource allocation…

Applications · Statistics 2020-05-25 Andrea Gabrio , Rachael Hunter , Alexina J. Mason , Gianluca Baio

Much attention has been devoted recently to the development of machine learning algorithms with the goal of improving treatment policies in healthcare. Reinforcement learning (RL) is a sub-field within machine learning that is concerned…

Research is a tertiary priority in the EHR, where the priorities are patient care and billing. Because of this, the data is not standardized or formatted in a manner easily adapted to machine learning approaches. Data may be missing for a…

Machine Learning · Computer Science 2017-07-25 Brett K. Beaulieu-Jones

Sequential decision-making systems routinely operate with missing or incomplete data. Classical reinforcement learning theory, which is commonly used to solve sequential decision problems, assumes Markovian observability, which may not hold…

Machine Learning · Computer Science 2025-08-07 MaryLena Bleile , Minh-Nhat Phung , Minh-Binh Tran

Reinforcement Learning (RL) has recently been applied to sequential estimation and prediction problems identifying and developing hypothetical treatment strategies for septic patients, with a particular focus on offline learning with…

Machine Learning · Computer Science 2020-11-24 Taylor W. Killian , Haoran Zhang , Jayakumar Subramanian , Mehdi Fatemi , Marzyeh Ghassemi

Predicting the health risks of patients using Electronic Health Records (EHR) has attracted considerable attention in recent years, especially with the development of deep learning techniques. Health risk refers to the probability of the…

Machine Learning · Computer Science 2022-11-15 Yuxi Liu , Shaowen Qin , Antonio Jimeno Yepes , Wei Shao , Zhenhao Zhang , Flora D. Salim

Most practical data science problems encounter missing data. A wide variety of solutions exist, each with strengths and weaknesses that depend upon the missingness-generating process. Here we develop a theoretical framework for training and…

Machine Learning · Computer Science 2022-11-15 Jahan C. Penny-Dimri , Christoph Bergmeir , Julian Smith

We consider the problem of recovering an expert's reward function with inverse reinforcement learning (IRL) when there are missing/incomplete state-action pairs or observations in the demonstrated trajectories. This issue of missing…

Machine Learning · Computer Science 2019-11-19 Tien Mai , Quoc Phong Nguyen , Kian Hsiang Low , Patrick Jaillet

Inverse reinforcement learning (IRL), which infers reward functions from demonstrations, is a valuable tool for modeling and understanding decision-making behavior. Many variants of IRL have been developed to capture complexities of human…

Machine Learning · Computer Science 2026-05-14 Leo Benac , Abhishek Sharma , Alihan Huyuk , Finale Doshi-Velez

Timely and personalized treatment decisions are essential across a wide range of healthcare settings where patient responses can vary significantly and evolve over time. Clinical data used to support these treatment decisions are often…

Machine Learning · Computer Science 2025-12-03 Qianyi Xu , Gousia Habib , Feng Wu , Dilruk Perera , Mengling Feng

Missing data is a common problem in real-world settings and particularly relevant in healthcare applications where researchers use Electronic Health Records (EHR) and results of observational studies to apply analytics methods. This issue…

Machine Learning · Statistics 2018-12-04 Dimitris Bertsimas , Agni Orfanoudaki , Colin Pawlowski
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