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Understanding how the brain switches from normal activity to an epileptic seizure is essential for improving seizure therapy, yet the underlying mechanisms remain largely unknown. In particular, seizure onset can be described as a critical…

Electroencephalogram (EEG) is a common tool used to understand brain activities. The data are typically obtained by placing electrodes at the surface of the scalp and recording the oscillations of currents passing through the electrodes.…

Signal Processing · Electrical Eng. & Systems 2021-02-19 Eddy Kwessi , Lloyd Edwards

Over the past few decades, electroencephalography (EEG) monitoring has become a pivotal tool for diagnosing neurological disorders, particularly for detecting seizures. Epilepsy, one of the most prevalent neurological diseases worldwide,…

Machine Learning · Computer Science 2025-08-08 Andrea Pollastro , Francesco Isgrò , Roberto Prevete

Purpose: Understanding fluctuations of seizure severity within individuals is important for defining treatment outcomes and response to therapy, as well as developing novel treatments for epilepsy. Current methods for grading seizure…

Alterations to structural and functional brain networks have been reported across many neurological conditions. However, the relationship between structure and function -- their coupling -- is relatively unexplored, particularly in the…

Epilepsy affects nearly 1% of the global population, of which two thirds can be treated by anti-epileptic drugs and a much lower percentage by surgery. Diagnostic procedures for epilepsy and monitoring are highly specialized and…

Signal Processing · Electrical Eng. & Systems 2020-01-20 Tennison Liu , Nhan Duy Truong , Armin Nikpour , Luping Zhou , Omid Kavehei

Epileptic seizures cause abnormal brain activity, and their unpredictability can lead to accidents, underscoring the need for long-term seizure prediction. Although seizures can be predicted by analyzing electroencephalogram (EEG) signals,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Guorui Lu , Jing Peng , Bingyuan Huang , Chang Gao , Todor Stefanov , Yong Hao , Qinyu Chen

Brain activity following stimulus presentation and during resting state are often the result of highly coordinated responses of large numbers of neurons both locally and globally. Coordinated activity of neurons can give rise to…

Applications · Statistics 2015-07-20 Carolina Euan , Hernando Ombao , Joaquin Ortega

Predicting seizure freedom is essential for tailoring epilepsy treatment. But accurate prediction remains challenging with traditional methods, especially with diverse patient populations. This study developed a deep learning-based graph…

Epilepsy is a neurological disorder that affects normal neural activity. These electrical activities can be recorded as signals containing information about the brain known as Electroencephalography (EEG) signals. Analysis of the EEG…

Signal Processing · Electrical Eng. & Systems 2025-07-10 Fatemeh Valipour , Zahra Valipour , Mani Garousi , Ali Khadem

Epilepsy is one of the most serious neurological diseases, affecting 1-2% of the world's population. The diagnosis of epilepsy depends heavily on the recognition of epileptic waves, i.e., disordered electrical brainwave activity in the…

Signal Processing · Electrical Eng. & Systems 2023-06-26 Junru Chen , Yang Yang , Tao Yu , Yingying Fan , Xiaolong Mo , Carl Yang

Epileptic seizure forecasting is a clinically important yet challenging problem in epilepsy research. Existing approaches predominantly rely on neural signals such as electroencephalography (EEG), which require specialized equipment and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Mingkai Zhai , Wei Wang , Zongsheng Li , Quanying Liu

This paper introduces an innovative framework designed for progressive (granular in time to onset) prediction of seizures through the utilization of a Deep Learning (DL) methodology based on non-invasive multi-modal sensor networks.…

Signal Processing · Electrical Eng. & Systems 2024-11-05 Ali Saeizadeh , Douglas Schonholtz , Joseph S. Neimat , Pedram Johari , Tommaso Melodia

Several high specificity and sensitivity seizure prediction methods with convolutional neural networks (CNNs) are reported. However, CNNs are computationally expensive and power hungry. These inconveniences make CNN-based methods hard to be…

Neural and Evolutionary Computing · Computer Science 2022-08-25 Fengshi Tian , Jie Yang , Shiqi Zhao , Mohamad Sawan

Developing a Brain-Computer Interface~(BCI) for seizure prediction can help epileptic patients have a better quality of life. However, there are many difficulties and challenges in developing such a system as a real-life support for…

Machine Learning · Computer Science 2017-02-20 Mohammad-Parsa Hosseini , Hamid Soltanian-Zadeh , Kost Elisevich , Dario Pompili

This work aims to develop an end-to-end solution for seizure onset detection. We design the SeizNet, a Convolutional Neural Network for seizure detection. To compare SeizNet with traditional machine learning approach, a baseline classifier…

Signal Processing · Electrical Eng. & Systems 2019-06-25 Mustafa Talha Avcu , Zhuo Zhang , Derrick Wei Shih Chan

Analyzing electroencephalogram (EEG) signals to detect the epileptic seizure status of a subject presents a challenge to existing technologies aimed at providing timely and efficient diagnosis. In this study, we aimed to detect interictal…

Signal Processing · Electrical Eng. & Systems 2024-10-25 Ruixin Lia , Guoxu Zhaoa , Dylan Richard Muir , Yuya Ling , Karla Burelo , Mina Khoei , Dong Wang , Yannan Xing , Ning Qiao

Electroencephalography (EEG) classification plays a key role in brain-computer interface (BCI) systems, yet it remains challenging due to the low signal-to-noise ratio, temporal variability of neural responses, and limited data…

Artificial Intelligence · Computer Science 2026-03-17 Aryan Patodiya , Hubert Cecotti

Magnetoencephalography (MEG) allows the non-invasive detection of interictal epileptiform discharges (IEDs). Clinical MEG analysis in epileptic patients traditionally relies on the visual identification of IEDs, which is time consuming and…

Accurately localizing the brain regions that triggers seizures and predicting whether a patient will be seizure-free after surgery are vital for surgical planning and patient management in drug-resistant epilepsy.…

Signal Processing · Electrical Eng. & Systems 2025-05-30 Syeda Abeera Amir , Artur Agaronyan , William Gaillard , Chima Oluigbo , Syed Muhammad Anwar