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Related papers: Biomedical Evidence Generation Engine

200 papers

How do we most effectively treat a disease or condition? Ideally, we could consult a database of evidence gleaned from clinical trials to answer such questions. Unfortunately, no such database exists; clinical trial results are instead…

Computation and Language · Computer Science 2020-05-15 Jay DeYoung , Eric Lehman , Ben Nye , Iain J. Marshall , Byron C. Wallace

We study the task of automatically finding evidence relevant to hypotheses in biomedical papers. Finding relevant evidence is an important step when researchers investigate scientific hypotheses. We introduce EvidenceBench to measure models…

Evidence-based medicine (EBM) plays a crucial role in the application of large language models (LLMs) in healthcare, as it provides reliable support for medical decision-making processes. Although it benefits from current…

Computation and Language · Computer Science 2025-03-24 Chengfeng Dou , Ying Zhang , Zhi Jin , Wenpin Jiao , Haiyan Zhao , Yongqiang Zhao , Zhengwei Tao

A major obstacle to the development of Natural Language Processing (NLP) methods in the biomedical domain is data accessibility. This problem can be addressed by generating medical data artificially. Most previous studies have focused on…

Computation and Language · Computer Science 2019-08-09 Zixu Wang , Julia Ive , Sumithra Velupillai , Lucia Specia

Verification of biomedical claims is critical for healthcare decision-making, public health policy and scientific research. We present an interactive biomedical claim verification system by integrating LLMs, transparent model explanations,…

Human-Computer Interaction · Computer Science 2025-03-03 Siting Liang , Daniel Sonntag

The rapid advancement of large language models (LLMs) has opened new boundaries in the extraction and synthesis of medical knowledge, particularly within evidence synthesis. This paper reviews the state-of-the-art applications of LLMs in…

Biomedical research results are being published at a high rate, and with existing search engines, the vast amount of published work is usually easily accessible. However, reproducing published results, either experimental data or…

Molecular Networks · Quantitative Biology 2017-06-19 Kai-Wen Liang , Qinsi Wang , Cheryl Telmer , Divyaa Ravichandran , Peter Spirtes , Natasa Miskov-Zivanov

Existing LLM-based medical question-answering systems lack citation generation and evaluation capabilities, raising concerns about their adoption in practice. In this work, we introduce \name, the first end-to-end framework that facilitates…

Computation and Language · Computer Science 2025-06-10 Xiao Wang , Mengjue Tan , Qiao Jin , Guangzhi Xiong , Yu Hu , Aidong Zhang , Zhiyong Lu , Minjia Zhang

Biomedical knowledge resources often either preserve evidence as unstructured text or compress it into flat triples that omit study design, provenance, and quantitative support. Here we present EvidenceNet, a disease-specific dataset of…

Computational Engineering, Finance, and Science · Computer Science 2026-04-15 Chang Zong , Sicheng Lv , Si-tu Xue , Huilin Zheng , Jian Wan , Lei Zhang

Evidence-based medicine (EBM) is at the forefront of modern healthcare, emphasizing the use of the best available scientific evidence to guide clinical decisions. Due to the sheer volume and rapid growth of medical literature and the high…

Computation and Language · Computer Science 2025-05-29 Zihan Xu , Haotian Ma , Gongbo Zhang , Yihao Ding , Chunhua Weng , Yifan Peng

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn

Synthesizing clinical evidence largely relies on systematic reviews of clinical trials and retrospective analyses from medical literature. However, the rapid expansion of publications presents challenges in efficiently identifying,…

Computation and Language · Computer Science 2024-10-30 Zifeng Wang , Lang Cao , Benjamin Danek , Qiao Jin , Zhiyong Lu , Jimeng Sun

Pre-consultation is a critical component of effective healthcare delivery. However, generating comprehensive pre-consultation questionnaires from complex, voluminous Electronic Medical Records (EMRs) is a challenging task. Direct Large…

Artificial Intelligence · Computer Science 2025-08-04 Ruiqing Ding , Qianfang Sun , Yongkang Leng , Hui Yin , Xiaojian Li

Misinformation in healthcare, from vaccine hesitancy to unproven treatments, poses risks to public health and trust in medical systems. While machine learning and natural language processing have advanced automated fact-checking, validating…

Computation and Language · Computer Science 2025-09-18 Mariano Barone , Antonio Romano , Giuseppe Riccio , Marco Postiglione , Vincenzo Moscato

Medical text generation aims to assist with administrative work and highlight salient information to support decision-making. To reflect the specific requirements of medical text, in this paper, we propose a set of metrics to evaluate the…

Computation and Language · Computer Science 2024-10-04 Yiqing Xie , Sheng Zhang , Hao Cheng , Pengfei Liu , Zelalem Gero , Cliff Wong , Tristan Naumann , Hoifung Poon , Carolyn Rose

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

Clinical evidence underpins informed healthcare decisions, yet integrating it into real-time practice remains challenging due to intensive workloads, complex procedures, and time constraints. This study presents Quicker, an LLM-powered…

We introduce an explainability method for biomedical hypothesis generation systems, built on top of the novel Hypothesis Generation Context Retriever framework. Our approach combines semantic graph-based retrieval and relevant…

Information Retrieval · Computer Science 2025-11-11 Ilya Tyagin , Saeideh Valipour , Aliaksandra Sikirzhytskaya , Michael Shtutman , Ilya Safro

Misinformation in healthcare, from vaccine hesitancy to unproven treatments, poses risks to public health and trust in medical systems. While machine learning and natural language processing have advanced automated fact-checking, validating…

Computation and Language · Computer Science 2025-09-18 Mariano Barone , Antonio Romano , Giuseppe Riccio , Marco Postiglione , Vincenzo Moscato

The rapid adoption of Electronic Health Records (EHRs) has been instrumental in streamlining administrative tasks, increasing transparency, and enabling continuity of care across providers. An unintended consequence of the increased…

Computation and Language · Computer Science 2024-04-02 Griffin Adams
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