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Electronic health records (EHR) offer unprecedented opportunities for in-depth clinical phenotyping and prediction of clinical outcomes. Combining multiple data sources is crucial to generate a complete picture of disease prevalence,…

Computation and Language · Computer Science 2022-12-01 Anna Munoz-Farre , Harry Rose , Sera Aylin Cakiroglu

Irregular sampling of time series in electronic health records (EHRs) is one of the main challenges for developing machine learning models. Additionally, the pattern of missing data in certain clinical variables is not at random but depends…

Machine Learning · Computer Science 2024-06-17 Hojjat Karami , David Atienza , Anisoara Ionescu

We propose a new tensor factorization method, called the Sparse Hierarchical-Tucker (Sparse H-Tucker), for sparse and high-order data tensors. Sparse H-Tucker is inspired by its namesake, the classical Hierarchical Tucker method, which aims…

Machine Learning · Computer Science 2016-10-26 Ioakeim Perros , Robert Chen , Richard Vuduc , Jimeng Sun

The recent adoption of Electronic Health Records (EHRs) by health care providers has introduced an important source of data that provides detailed and highly specific insights into patient phenotypes over large cohorts. These datasets, in…

Probabilistic Temporal Tensor Factorization (PTTF) is an effective algorithm to model the temporal tensor data. It leverages a time constraint to capture the evolving properties of tensor data. Nowadays the exploding dataset demands a large…

Machine Learning · Statistics 2016-11-14 Guangxi Li , Zenglin Xu , Linnan Wang , Jinmian Ye , Irwin King , Michael Lyu

Electronic phenotyping is the task of ascertaining whether an individual has a medical condition of interest by analyzing their medical record and is foundational in clinical informatics. Increasingly, electronic phenotyping is performed…

Machine Learning · Statistics 2019-01-08 Daisy Yi Ding , Chloé Simpson , Stephen Pfohl , Dave C. Kale , Kenneth Jung , Nigam H. Shah

Objective: The coupling between neuronal populations and its magnitude have been shown to be informative for various clinical applications. One method to estimate brain connectivity is with electroencephalography (EEG) from which the…

Computational Engineering, Finance, and Science · Computer Science 2017-05-08 Loukianos Spyrou , Mario Parra , Javier Escudero

Initial hours of hospital admission impact clinical trajectory, but early clinical decisions often suffer due to data paucity. With clustering analysis for vital signs within six hours of admission, patient phenotypes with distinct…

In exploratory tensor mining, a common problem is how to analyze a set of variables across a set of subjects whose observations do not align naturally. For example, when modeling medical features across a set of patients, the number and…

Machine Learning · Computer Science 2017-03-14 Ioakeim Perros , Evangelos E. Papalexakis , Fei Wang , Richard Vuduc , Elizabeth Searles , Michael Thompson , Jimeng Sun

The paper presents a systematic review of state-of-the-art approaches to identify patient cohorts using electronic health records. It gives a comprehensive overview of the most commonly de-tected phenotypes and its underlying data sets.…

Machine Learning · Statistics 2017-07-25 Norman Hiob , Stefan Lessmann

Tensor factorization has been proved as an efficient unsupervised learning approach for health data analysis, especially for computational phenotyping, where the high-dimensional Electronic Health Records (EHRs) with patients' history of…

Machine Learning · Computer Science 2022-11-04 Jing Ma , Qiuchen Zhang , Jian Lou , Li Xiong , Sivasubramanium Bhavani , Joyce C. Ho

Detailed phenotype information is fundamental to accurate diagnosis and risk estimation of diseases. As a rich source of phenotype information, electronic health records (EHRs) promise to empower diagnostic variant interpretation. However,…

Machine Learning · Computer Science 2023-04-28 Shenghan Zhang , Haoxuan Li , Ruixiang Tang , Sirui Ding , Laila Rasmy , Degui Zhi , Na Zou , Xia Hu

Tensor factorization models offer an effective approach to convert massive electronic health records into meaningful clinical concepts (phenotypes) for data analysis. These models need a large amount of diverse samples to avoid population…

Machine Learning · Computer Science 2017-10-13 Yejin Kim , Jimeng Sun , Hwanjo Yu , Xiaoqian Jiang

This study proposes a risk prediction method based on a Multi-Scale Temporal Alignment Network (MSTAN) to address the challenges of temporal irregularity, sampling interval differences, and multi-scale dynamic dependencies in Electronic…

Machine Learning · Computer Science 2025-11-27 Wei-Chen Chang , Lu Dai , Ting Xu

Echocardiography is widely used to clinical practice for diagnosis and treatment, e.g., on the common congenital heart defects. The traditional manual manipulation is error-prone due to the staff shortage, excess workload, and less…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Fuhai Chen , Rongrong Ji , Chengpeng Dai , Xuri Ge , Shengchuang Zhang , Xiaojing Ma , Yue Gao

Accurate prediction of the transmission of epidemic diseases such as COVID-19 is crucial for implementing effective mitigation measures. In this work, we develop a tensor method to predict the evolution of epidemic trends for many regions…

Machine Learning · Computer Science 2021-03-19 Nikos Kargas , Cheng Qian , Nicholas D. Sidiropoulos , Cao Xiao , Lucas M. Glass , Jimeng Sun

The breadth, scale, and temporal granularity of modern electronic health records (EHR) systems offers great potential for estimating personalized and contextual patient health trajectories using sequential deep learning. However, learning…

Electronic Health Record (EHR) data can be represented as discrete counts over a high dimensional set of possible procedures, diagnoses, and medications. Supervised topic models present an attractive option for incorporating EHR data as…

Machine Learning · Computer Science 2019-11-21 Jason Ren , Russell Kunes , Finale Doshi-Velez

Because tensor data appear more and more frequently in various scientific researches and real-world applications, analyzing the relationship between tensor features and the univariate outcome becomes an elementary task in many fields. To…

Machine Learning · Computer Science 2019-12-04 Jiaqi Zhang , Beilun Wang

We propose TAMER, a Test-time Adaptive MoE-driven framework for Electronic Health Record (EHR) Representation learning. TAMER introduces a framework where a Mixture-of-Experts (MoE) architecture is co-designed with Test-Time Adaptation…

Machine Learning · Computer Science 2025-03-19 Yinghao Zhu , Xiaochen Zheng , Ahmed Allam , Michael Krauthammer