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Central to our understanding of chemical reactivity is the principle of mass conservation, which is fundamental for ensuring physical consistency, balancing equations, and guiding reaction design. However, data-driven computational models…

Machine Learning · Computer Science 2025-02-19 Joonyoung F. Joung , Mun Hong Fong , Nicholas Casetti , Jordan P. Liles , Ne S. Dassanayake , Connor W. Coley

Inverse design refers to the problem of optimizing the input of an objective function in order to enact a target outcome. For many real-world engineering problems, the objective function takes the form of a simulator that predicts how the…

The high dimensionality and complex dynamics of turbulent flows in urban street canyons present significant challenges for wind and environmental engineering, particularly in addressing air quality, pollutant dispersion, and extreme wind…

Fluid Dynamics · Physics 2025-01-24 Tomek Jaroslawski , Aakash Patil , Beverley McKeon

Deep learning provides a versatile suite of methods for extracting structured information from complex datasets, enabling deeper understanding of underlying fluid dynamic phenomena. The field of turbulence modeling, in particular, benefits…

Machine Learning · Computer Science 2025-07-31 Anuraj Maurya

Turing's mechanism is often invoked to explain periodic patterns in nature, although direct experimental support is scarce. Turing patterns form in reaction-diffusion systems when the activating species diffuse much slower than the…

Biological Physics · Physics 2024-03-15 Lucas Menou , Chengjie Luo , David Zwicker

The recent advent of advanced microfabrication capabilities of microfluidic devices has driven attention towards the behavior of particles in inertial flows within microchannels for applications related to the separation and concentration…

Fluid Dynamics · Physics 2018-12-03 Mike Garcia , Sumita Pennathur

Patterns are ubiquitous in nature, but how they form is often unclear. Turing developed a seminal theory to explain patterns based on reactions that counteract the equalizing tendency of diffusion. These reactions require continuous energy…

Biological Physics · Physics 2025-11-24 Cathelijne ter Burg , David Zwicker

The reconstruction of unsteady flow fields from limited measurements is a challenging and crucial task for many engineering applications. Machine learning models are gaining popularity for solving this problem due to their ability to learn…

Fluid Dynamics · Physics 2026-01-09 Marc Amorós-Trepat , Luis Medrano-Navarro , Qiang Liu , Luca Guastoni , Nils Thuerey

We study the asymptotic behaviour of a system of nonlinear reaction--diffusion--advection equations in a domain consisting of two bulk regions connected via microscopic channels distributed within a thin membrane. Both the width of the…

Analysis of PDEs · Mathematics 2025-12-15 Lucas M. Fix , Gianna Götzmann , Malte A. Peter , Jan-F. Pietschmann

The inverse design of metasurfaces faces inherent challenges due to the nonlinear and highly complex relationship between geometric configurations and their electromagnetic behavior. Traditional optimization approaches often suffer from…

Cells control fluid flows with a spatial and temporal precision that far exceeds the capabilities of current microfluidic technologies. Cells achieve this superior spatio-temporal control by harnessing dynamic networks of cytoskeleton and…

Soft Condensed Matter · Physics 2025-05-26 Fan Yang , Shichen Liu , Heun Jin Lee , Rob Phillips , Matt Thomson

The interaction of neural networks with physical equations offers a wide range of applications. We provide a method which enables a neural network to transform objects subject to given physical constraints. Therefore an U-Net architecture…

Artificial Intelligence · Computer Science 2021-03-22 Lukas Harsch , Johannes Burgbacher , Stefan Riedelbauch

Inertial pumping is a promising new method of moving fluids through microchannels but many of its properties remain unexplored. In this work, inertial flow rates are investigated for different channel lengths, operating temperatures, and…

Fluid Dynamics · Physics 2022-02-03 Pavel E. Kornilovitch , Tyler Cochell , Alexander N. Govyadinov

As modern electronic devices are increasingly miniaturized and integrated, their performance relies more heavily on effective thermal management. Two-phase cooling methods enhanced by porous surfaces, which capitalize on thin-film…

Machine Learning · Computer Science 2023-10-31 Jonathan Tammer Eweis-LaBolle , Chuanning Zhao , Yoonjin Won , Ramin Bostanabad

Flow-based generative models provide strong unconditional priors for inverse problems, but guiding their dynamics for conditional generation remains challenging. Recent work casts training-free conditional generation in flow models as an…

Image and Video Processing · Electrical Eng. & Systems 2026-02-02 George Webber , Alexander Denker , Riccardo Barbano , Andrew J Reader

We introduce a method for solving the "inverse" phase equilibria problem: How should the interactions among a collection of molecular species be designed in order to achieve a target phase diagram? Using techniques from convex optimization…

Soft Condensed Matter · Physics 2023-06-06 Fan Chen , William M. Jacobs

Microchannel heat sinks are an efficient cooling method for semiconductor packages. However, to properly cool increasingly complex and thermally dense circuits, microchannel designs should be improved and expanded on. In this paper,…

Fluid Dynamics · Physics 2022-12-12 Ante Sikirica , Luka Grbčić , Lado Kranjčević

We study an inverse design problem for the linear multiple fragmentation equation arising in particle dynamics. Our objective is to reconstruct an unknown initial size distribution that evolves, under a prescribed fragmentation law, into a…

Optimization and Control · Mathematics 2026-02-20 Arijit Das

Aligned superhydrophobic surfaces with the same texture orientation reduce drag in the channel and generate secondary flows transverse to the direction of the applied pressure gradient. Here we show that a transverse shear can be easily…

In Nature, liquids often circulate in channels textured with leaflets, cilia or porous walls that deform with the flow. These soft structures are optimized to passively control flows and inspire the design of novel microfluidic and soft…

Soft Condensed Matter · Physics 2020-08-19 Martin Brandenbourger , Adrien Dangremont , Rudolf Sprik , Corentin Coulais