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Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…

Whole abdominal organ segmentation is important in diagnosing abdomen lesions, radiotherapy, and follow-up. However, oncologists' delineating all abdominal organs from 3D volumes is time-consuming and very expensive. Deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Xiangde Luo , Wenjun Liao , Jianghong Xiao , Jieneng Chen , Tao Song , Xiaofan Zhang , Kang Li , Dimitris N. Metaxas , Guotai Wang , Shaoting Zhang

Annotating 3D medical images demands expert knowledge and is time-consuming. As a result, semi-supervised learning (SSL) approaches have gained significant interest in 3D medical image segmentation. The significant size differences among…

Computer Vision and Pattern Recognition · Computer Science 2024-10-21 Yuliang Gu , Yepeng Liu , Zhichao Sun , Jinchi Zhu , Yongchao Xu , Laurent Najman

Nonlinear image registration continues to be a fundamentally important tool in medical image analysis. Diagnostic tasks, image-guided surgery and radiotherapy as well as motion analysis all rely heavily on accurate intra-patient alignment.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Mattias P. Heinrich

Purpose: The purpose of this paper is to present a method for real-time 2D-3D non-rigid registration using a single fluoroscopic image. Such a method can find applications in surgery, interventional radiology and radiotherapy. By estimating…

Image and Video Processing · Electrical Eng. & Systems 2023-03-28 François Lecomte , Jean-Louis Dillenseger , Stéphane Cotin

The task of labeling multiple organs for segmentation is a complex and time-consuming process, resulting in a scarcity of comprehensively labeled multi-organ datasets while the emergence of numerous partially labeled datasets. Current…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Xiaoyu Liu , Linhao Qu , Ziyue Xie , Yonghong Shi , Zhijian Song

Many existing learning-based deformable image registration methods impose constraints on deformation fields to ensure they are globally smooth and continuous. However, this assumption does not hold in cardiac image registration, where…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Hang Zhang , Xiang Chen , Renjiu Hu , Dongdong Liu , Gaolei Li , Rongguang Wang

Statistical shape modeling (SSM) characterizes anatomical variations in a population of shapes generated from medical images. SSM requires consistent shape representation across samples in shape cohort. Establishing this representation…

Computer Vision and Pattern Recognition · Computer Science 2022-03-17 Riddhish Bhalodia , Shireen Elhabian , Jadie Adams , Wenzheng Tao , Ladislav Kavan , Ross Whitaker

Efficient organ segmentation is the precondition of various quantitative analysis. Segmenting the pancreas from abdominal CT images is a challenging task because of its high anatomical variability in shape, size and location. What's more,…

Computer Vision and Pattern Recognition · Computer Science 2020-03-10 Jinchan He , Xiaxia Yu , Chudong Cai , Yi Gao

The loss function of an unsupervised multimodal image registration framework has two terms, i.e., a metric for similarity measure and regularization. In the deep learning era, researchers proposed many approaches to automatically learn the…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Zhe Xu , Jiangpeng Yan , Jie Luo , William Wells , Xiu Li , Jayender Jagadeesan

For the one billion sufferers of respiratory disease, managing their disease with inhalers crucially influences their quality of life. Generic treatment plans could be improved with the aid of computational models that account for…

Ultrasound deformable registration estimates spatial transformations between pairs of deformed ultrasound images, which is crucial for capturing biomechanical properties and enhancing diagnostic accuracy in diseases such as thyroid nodules…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Yimeng Geng , Mingyang Zhao , Fan Xu , Guanglin Cao , Gaofeng Meng , Hongbin Liu

Medical image registration is one of the key processing steps for biomedical image analysis such as cancer diagnosis. Recently, deep learning based supervised and unsupervised image registration methods have been extensively studied due to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Boah Kim , Jieun Kim , June-Goo Lee , Dong Hwan Kim , Seong Ho Park , Jong Chul Ye

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer, with most cases diagnosed at stage IV and a five-year overall survival rate below 5%. Early detection and prognosis modeling are crucial for improving patient outcomes…

Machine Learning · Computer Science 2025-04-02 David Le , Ramon Correa-Medero , Amara Tariq , Bhavik Patel , Motoyo Yano , Imon Banerjee

Objective: Four-dimensional computed tomography (4DCT) imaging consists in reconstructing a CT acquisition into multiple phases to track internal organ and tumor motion. It is commonly used in radiotherapy treatment planning to establish…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Yi-Heng Cao , Vincent Bourbonne , François Lucia , Ulrike Schick , Julien Bert , Vincent Jaouen , Dimitris Visvikis

Estimating accurate high-dimensional transformations remains very challenging, especially in a clinical setting. In this paper, we introduce a multiscale parameterization of deformations to enhance registration and atlas estimation in the…

Optimization and Control · Mathematics 2025-01-31 Fleur Gaudfernau , Eléonore Blondiaux , Stéphanie Allassonnière , Erwan Le Pennec

The success of deep convolutional neural networks on image classification and recognition tasks has led to new applications in very diversified contexts, including the field of medical imaging. In this paper we investigate and propose…

Computer Vision and Pattern Recognition · Computer Science 2018-02-14 Alexey A. Novikov , Dimitrios Lenis , David Major , Jiri Hladůvka , Maria Wimmer , Katja Bühler

Accurate molecular subtype classification is essential for personalized breast cancer treatment, yet conventional immunohistochemical analysis relies on invasive biopsies and is prone to sampling bias. Although dynamic contrast-enhanced…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Sen Zeng , Hong Zhou , Zheng Zhu , Yang Liu

Myocardial motion and deformation are rich descriptors that characterize cardiac function. Image registration, as the most commonly used technique for myocardial motion tracking, is an ill-posed inverse problem which often requires prior…

Image and Video Processing · Electrical Eng. & Systems 2022-06-09 Chen Qin , Shuo Wang , Chen Chen , Wenjia Bai , Daniel Rueckert

Physical rehabilitation exercises suggested by healthcare professionals can help recovery from various musculoskeletal disorders and prevent re-injury. However, patients' engagement tends to decrease over time without direct supervision,…

Human-Computer Interaction · Computer Science 2025-04-22 Aleksa Marusic , Sao Mai Nguyen , Adriana Tapus
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