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Large genomic and imaging datasets can be used to train models that learn meaningful representations of cellular systems. Across domains, model performance improves predictably with dataset size and compute budget, providing a basis for…

Quantitative Methods · Quantitative Biology 2026-02-23 Gokul Gowri , Igor Sadalski , Dan Raviv , Peng Yin , Jonathan Rosenfeld , Allon M. Klein

In recent years, Whole Genome Sequencing (WGS) evolved from a futuristic-sounding research project to an increasingly affordable technology for determining complete genome sequences of complex organisms, including humans. This prompts a…

Cryptography and Security · Computer Science 2015-02-17 Erman Ayday , Emiliano De Cristofaro , Jean-Pierre Hubaux , Gene Tsudik

In the context of supervised learning of a function by a neural network, we claim and empirically verify that the neural network yields better results when the distribution of the data set focuses on regions where the function to learn is…

Machine Learning · Statistics 2022-09-28 Paul Novello , Gaël Poëtte , David Lugato , Pietro Congedo

The combination of multiple classifiers using ensemble methods is increasingly important for making progress in a variety of difficult prediction problems. We present a comparative analysis of several ensemble methods through two case…

Machine Learning · Computer Science 2013-09-20 Sean Whalen , Gaurav Pandey

The motivation of this work is to improve the performance of standard stacking approaches or ensembles, which are composed of simple, heterogeneous base models, through the integration of the generation and selection stages for regression…

Machine Learning · Statistics 2014-03-31 Roberto Aldave , Jean-Pierre Dussault

In many applications of machine learning, certain categories of examples may be underrepresented in the training data, causing systems to underperform on such "few-shot" cases at test time. A common remedy is to perform data augmentation,…

Computation and Language · Computer Science 2021-02-03 Kenton Lee , Kelvin Guu , Luheng He , Tim Dozat , Hyung Won Chung

Automated data augmentation has shown superior performance in image recognition. Existing works search for dataset-level augmentation policies without considering individual sample variations, which are likely to be sub-optimal. On the…

Machine Learning · Computer Science 2020-12-23 Fengwei Zhou , Jiawei Li , Chuanlong Xie , Fei Chen , Lanqing Hong , Rui Sun , Zhenguo Li

Deep learning models tend to memorize training data, which hurts their ability to generalize to under-represented classes. We empirically study a convolutional neural network's internal representation of imbalanced image data and measure…

Machine Learning · Computer Science 2022-10-19 Damien Dablain , Colin Bellinger , Bartosz Krawczyk , Nitesh Chawla

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

Quantitative Methods · Quantitative Biology 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

Despite their empirical success, neural networks still have difficulty capturing compositional aspects of natural language. This work proposes a simple data augmentation approach to encourage compositional behavior in neural models for…

Computation and Language · Computer Science 2020-11-19 Demi Guo , Yoon Kim , Alexander M. Rush

Extreme learning machine (ELM) as a neural network algorithm has shown its good performance, such as fast speed, simple structure etc, but also, weak robustness is an unavoidable defect in original ELM for blended data. We present a new…

Machine Learning · Computer Science 2014-09-24 Bo Han , Bo He , Rui Nian , Mengmeng Ma , Shujing Zhang , Minghui Li , Amaury Lendasse

Next-generation sequencing (NGS) technologies have enabled affordable sequencing of billions of short DNA fragments at high throughput, paving the way for population-scale genomics. Genomics data analytics at this scale requires overcoming…

Databases · Computer Science 2019-10-11 Darryl Ho , Jialin Ding , Sanchit Misra , Nesime Tatbul , Vikram Nathan , Vasimuddin Md , Tim Kraska

Protein solubility plays a critical role in improving production yield of recombinant proteins in biocatalyst and pharmaceutical field. To some extent, protein solubility can represent the function and activity of biocatalysts which are…

Quantitative Methods · Quantitative Biology 2018-11-20 X. Han , L. Zhang , K. Zhou , X. Wang

We propose a new strategy to improve the accuracy and robustness of image classification. First, we train a baseline CNN model. Then, we identify challenging regions in the feature space by identifying all misclassified samples, and…

Computer Vision and Pattern Recognition · Computer Science 2023-02-23 Fadoua Khmaissia , Hichem Frigui

This paper describes a novel approach to learning term-weighting schemes (TWSs) in the context of text classification. In text mining a TWS determines the way in which documents will be represented in a vector space model, before applying a…

Neural and Evolutionary Computing · Computer Science 2014-10-08 Hugo Jair Escalante , Mauricio A. García-Limón , Alicia Morales-Reyes , Mario Graff , Manuel Montes-y-Gómez , Eduardo F. Morales

Nearly all model algorithms used in machine learning use two different sets of parameters: the training parameters and the meta-parameters (hyperparameters). While the training parameters are learned during the training phase, the values of…

Machine Learning · Computer Science 2020-03-31 Razvan Andonie , Adrian-Catalin Florea

We introduce a new machine learning approach for image segmentation that uses a neural network to model the conditional energy of a segmentation given an image. Our approach, combinatorial energy learning for image segmentation (CELIS)…

Computer Vision and Pattern Recognition · Computer Science 2016-09-27 Jeremy Maitin-Shepard , Viren Jain , Michal Januszewski , Peter Li , Pieter Abbeel

Learning in deep weight spaces (DWS), where neural networks process the weights of other neural networks, is an emerging research direction, with applications to 2D and 3D neural fields (INRs, NeRFs), as well as making inferences about…

Machine Learning · Computer Science 2024-11-12 Aviv Shamsian , Aviv Navon , David W. Zhang , Yan Zhang , Ethan Fetaya , Gal Chechik , Haggai Maron

We propose a training-free approach to improve sentence embeddings leveraging test-time compute by applying generative text models for data augmentation at inference time. Unlike conventional data augmentation that utilises synthetic…

Computation and Language · Computer Science 2025-09-09 Manuel Frank , Haithem Afli

The Third-Generation in DNA sequencing has emerged in the last few years using new technologies that allow the production of long-read sequences. Applications of the Third-Generation sequencing enable real-time and on-site data production,…

Populations and Evolution · Quantitative Biology 2019-02-26 Hyunjin Shim
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